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| | TCF7 | Transcription factor 7. (496 aa) |
| | PPP1R14B | Uncharacterized protein. (208 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | ACTL8 | Actin like 8; Belongs to the actin family. (366 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (589 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2A. (160 aa) |
| | SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | GSTM3 | Glutathione S-transferase. (225 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | GSTP1 | Glutathione S-transferase pi 1; Belongs to the GST superfamily. (210 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1599 aa) |
| | SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1268 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa) |
| | ENSMNEP00000042658 | annotation not available (67 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | APC | APC regulator of WNT signaling pathway. (2864 aa) |
| | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1105 aa) |
| | E2F3 | E2F transcription factor 3. (465 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (399 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | ENSMNEP00000041206 | Uncharacterized protein; Belongs to the actin family. (163 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) |
| | MGST1 | Microsomal glutathione S-transferase 1. (155 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | DPF1 | Double PHD fingers 1. (414 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (463 aa) |
| | FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (627 aa) |
| | ENSMNEP00000038177 | Uncharacterized protein; Belongs to the actin family. (156 aa) |
| | SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1583 aa) |
| | ENSMNEP00000037627 | Uncharacterized protein. (339 aa) |
| | BRD7 | Bromodomain containing 7. (598 aa) |
| | AXIN1 | Axin 1. (867 aa) |
| | MGST3 | Microsomal glutathione S-transferase 3. (166 aa) |
| | ENSMNEP00000036565 | HMG box domain-containing protein. (177 aa) |
| | E2F2 | E2F transcription factor 2. (439 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (690 aa) |
| | KEAP1 | Kelch like ECH associated protein 1. (624 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | SHC2 | Uncharacterized protein. (572 aa) |
| | SHC1 | SHC adaptor protein 1. (584 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (668 aa) |
| | TXNRD3 | Thioredoxin reductase 3. (642 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (523 aa) |
| | ARID1A | AT-rich interaction domain 1A. (2290 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (270 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1403 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | ACTRT2 | Actin related protein T2; Belongs to the actin family. (377 aa) |
| | ACTL7A | Actin like 7A; Belongs to the actin family. (435 aa) |
| | GSTA3 | Glutathione S-transferase alpha 3. (222 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | ENSMNEP00000028540 | Uncharacterized protein. (139 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | ENSMNEP00000027902 | Protein kinase domain-containing protein. (365 aa) |
| | TGFA | Transforming growth factor alpha. (166 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | ENSMNEP00000027418 | Uncharacterized protein; Belongs to the GST superfamily. (202 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | IGF2 | Insulin like growth factor 2. (236 aa) |
| | SHC3 | SHC adaptor protein 3. (598 aa) |
| | CSNK1A1 | Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa) |
| | LOC105497405 | Uncharacterized protein. (240 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa) |
| | TXNRD2 | Thioredoxin reductase 2. (523 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | ACTL6B | Actin like 6B; Belongs to the actin family. (447 aa) |
| | ENSMNEP00000024033 | Uncharacterized protein. (265 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | MGST2 | Microsomal glutathione S-transferase 2. (147 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (203 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (562 aa) |
| | LOC105497406 | GST N-terminal domain-containing protein. (67 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | CSNK1A1L | Casein kinase 1 alpha 1 like. (243 aa) |
| | ENSMNEP00000021019 | Glutathione S-transferase. (213 aa) |
| | SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (531 aa) |
| | ACTB | Actin beta. (379 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) |
| | ENSMNEP00000019824 | Uncharacterized protein. (194 aa) |
| | CEP152 | Centrosomal protein 152. (1703 aa) |
| | NQO1 | NAD(P)H quinone dehydrogenase 1. (274 aa) |
| | ARID2 | AT-rich interaction domain 2. (1836 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (508 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | PBRM1 | Polybromo 1. (1709 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2301 aa) |
| | GSTO2 | Glutathione S-transferase omega 2; Belongs to the GST superfamily. (243 aa) |
| | ENSMNEP00000017273 | Protein kinase domain-containing protein. (311 aa) |
| | ELK1 | ETS transcription factor ELK1. (428 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (606 aa) |
| | GAB1 | GRB2 associated binding protein 1. (724 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa) |
| | ENSMNEP00000016378 | Protein kinase domain-containing protein. (652 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (260 aa) |
| | TXNRD1 | Thioredoxin reductase 1. (647 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | ENSMNEP00000015304 | Uncharacterized protein. (358 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa) |
| | ACTL6A | Actin like 6A; Belongs to the actin family. (420 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | HMOX1 | Heme oxygenase 1. (288 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1677 aa) |
| | GSTO1 | Uncharacterized protein; Belongs to the GST superfamily. (252 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | DPF3 | Double PHD fingers 3. (412 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (718 aa) |
| | RB1 | RB transcriptional corepressor 1. (928 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa) |
| | ENSMNEP00000011545 | Uncharacterized protein. (81 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | FRAT1 | FRAT regulator of WNT signaling pathway 1. (234 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (427 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | PIK3R2 | Uncharacterized protein. (668 aa) |
| | GSTM4 | Glutathione S-transferase mu 4; Belongs to the GST superfamily. (218 aa) |
| | GSTT2B | Uncharacterized protein; Belongs to the GST superfamily. (244 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (618 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1. (361 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | PHF10 | PHD finger protein 10. (498 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (763 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa) |
| | ACTRT1 | Actin related protein T1; Belongs to the actin family. (375 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | ARID1B | AT-rich interaction domain 1B. (1539 aa) |
| | GSTA4 | Glutathione S-transferase alpha 4. (222 aa) |
| | POLK | DNA polymerase kappa. (870 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | ACTL7B | Actin like 7B; Belongs to the actin family. (415 aa) |
| | ACTG1 | Actin gamma 1. (377 aa) |
| | TPTE2 | Uncharacterized protein. (558 aa) |
| | SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | ENSMNEP00000001669 | Uncharacterized protein. (77 aa) |
| | FRAT2 | FRAT regulator of WNT signaling pathway 2. (233 aa) |
| | ENSMNEP00000001215 | Uncharacterized protein. (87 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | ENSMNEP00000000907 | Uncharacterized protein. (241 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | AXIN2 | Axin 2. (844 aa) |
