STRINGSTRING
LOC105491641 LOC105491641 LOC105482638 LOC105482638 HLA-DMA HLA-DMA C6 C6 FCGR1A FCGR1A CD28 CD28 CTSG CTSG LOC105470432 LOC105470432 ENSMNEP00000020365 ENSMNEP00000020365 ENSMNEP00000020833 ENSMNEP00000020833 ACTN4 ACTN4 ENSMNEP00000021289 ENSMNEP00000021289 ENSMNEP00000022013 ENSMNEP00000022013 LOC105485223 LOC105485223 ENSMNEP00000022556 ENSMNEP00000022556 H2AZ2 H2AZ2 FCGR2B FCGR2B ENSMNEP00000024768 ENSMNEP00000024768 C8A C8A ENSMNEP00000025520 ENSMNEP00000025520 C9 C9 H2AZ1 H2AZ1 H2BC15 H2BC15 C7 C7 LOC105477893 LOC105477893 ENSMNEP00000028604 ENSMNEP00000028604 ACTN1 ACTN1 LOC105481870 LOC105481870 TNF TNF H2AC1 H2AC1 C1QB C1QB H2BC18 H2BC18 TRAC TRAC HLA-DQA1 HLA-DQA1 GRIN2A GRIN2A C3 C3 CD40LG CD40LG LOC105498220 LOC105498220 RO60 RO60 TRAV22 TRAV22 C8B C8B MACROH2A2 MACROH2A2 HLA-DPA1 HLA-DPA1 C1S C1S SNRPD1 SNRPD1 ABCF2 ABCF2 IL10 IL10 C4A C4A ENSMNEP00000038649 ENSMNEP00000038649 HLA-DOB HLA-DOB LOC105474413 LOC105474413 LOC105499692 LOC105499692 MROH2B MROH2B LOC105474426 LOC105474426 LOC105499748 LOC105499748 ENSMNEP00000044636 ENSMNEP00000044636 IFNG IFNG ENSMNEP00000016015 ENSMNEP00000016015 CD86 CD86 MACROH2A1 MACROH2A1 ENSMNEP00000015048 ENSMNEP00000015048 LOC105499746 LOC105499746 GRIN2B GRIN2B ENSMNEP00000012828 ENSMNEP00000012828 C1RL C1RL HLA-DPB1 HLA-DPB1 ENSMNEP00000010506 ENSMNEP00000010506 ENSMNEP00000010486 ENSMNEP00000010486 LOC105476302 LOC105476302 TRIM11 TRIM11 C8G C8G CD80 CD80 LOC105469173 LOC105469173 SSB SSB LOC105482587 LOC105482587 H2AC20 H2AC20 LOC105482591 LOC105482591 SNRPB SNRPB ENSMNEP00000006547 ENSMNEP00000006547 TRIM21 TRIM21 H3C13 H3C13 H2AJ H2AJ LOC105482638-9 LOC105482638-9 LOC105482638-8 LOC105482638-8 LOC105482638-7 LOC105482638-7 ELANE ELANE H2BC5 H2BC5 LOC105491648 LOC105491648 LOC105499682 LOC105499682 ENSMNEP00000004997 ENSMNEP00000004997 LOC105482586 LOC105482586 LOC105482579-2 LOC105482579-2 LOC105470433 LOC105470433 H2AX H2AX SNRPD3 SNRPD3 ENSMNEP00000004521 ENSMNEP00000004521 LOC105491665 LOC105491665 LOC105482638-6 LOC105482638-6 PRTN3 PRTN3 LOC105482573 LOC105482573 LOC105482638-5 LOC105482638-5 HLA-DRA HLA-DRA H3-4 H3-4 H2AC6 H2AC6 H2BC11 H2BC11 ENSMNEP00000003706 ENSMNEP00000003706 LOC105482579 LOC105482579 ENSMNEP00000003373 ENSMNEP00000003373 H2BC8 H2BC8 LOC105491642 LOC105491642 H1-5 H1-5 LOC105482638-4 LOC105482638-4 C1QC C1QC LOC105478976 LOC105478976 TRIM58 TRIM58 LOC105491667 LOC105491667 LOC105497787 LOC105497787 H2BC6 H2BC6 H2AC7 H2AC7 H2AW H2AW LOC105478977 LOC105478977 LOC105482572 LOC105482572 LOC105482571 LOC105482571 LOC105482560 LOC105482560 H2AC14 H2AC14 H2BC3 H2BC3 ENSMNEP00000002245 ENSMNEP00000002245 H2AC12 H2AC12 CD40 CD40 ENSMNEP00000002194 ENSMNEP00000002194 C5 C5 H2AC21 H2AC21 H1-4 H1-4 H2BC1 H2BC1 HLA-DOA HLA-DOA LOC105491634 LOC105491634 LOC105478980 LOC105478980 H2BU1 H2BU1 ENSMNEP00000001463 ENSMNEP00000001463 C1R C1R LOC112422912 LOC112422912 ENSMNEP00000001351 ENSMNEP00000001351 H2BC14 H2BC14 LOC105482638-3 LOC105482638-3 ENSMNEP00000000889 ENSMNEP00000000889 ENSMNEP00000000821 ENSMNEP00000000821 LOC105466836 LOC105466836 LOC105491644 LOC105491644 LOC105482638-2 LOC105482638-2 LOC105491635 LOC105491635
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105491641Uncharacterized LOC105491641. (103 aa)
LOC105482638Histone H3; Belongs to the histone H3 family. (136 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa)
C6Complement C6. (934 aa)
FCGR1AUncharacterized protein. (357 aa)
CD28CD28 molecule. (220 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
LOC105470432Ig-like domain-containing protein; Belongs to the MHC class II family. (260 aa)
ENSMNEP00000020365Histone domain-containing protein. (123 aa)
ENSMNEP00000020833Ig-like domain-containing protein. (145 aa)
ACTN4Actinin alpha 4. (931 aa)
ENSMNEP00000021289Ig-like domain-containing protein. (182 aa)
ENSMNEP00000022013Uncharacterized protein. (328 aa)
LOC105485223NTR domain-containing protein. (131 aa)
ENSMNEP00000022556Histone H2B; Belongs to the histone H2B family. (134 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
FCGR2BUncharacterized protein. (313 aa)
ENSMNEP00000024768Histone H2A; Belongs to the histone H2A family. (126 aa)
C8AComplement C8 alpha chain. (584 aa)
ENSMNEP00000025520Ig-like domain-containing protein. (194 aa)
C9Complement C9. (561 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (166 aa)
C7Complement C7. (843 aa)
LOC105477893Uncharacterized protein. (1747 aa)
ENSMNEP00000028604IGv domain-containing protein. (139 aa)
ACTN1Actinin alpha 1. (914 aa)
LOC105481870Histone H4. (103 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
H2AC1Histone H2A; Belongs to the histone H2A family. (131 aa)
C1QBComplement C1q B chain. (253 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (134 aa)
TRACT cell receptor alpha constant. (110 aa)
HLA-DQA1Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (267 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
C3Complement C3. (1642 aa)
CD40LGCD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (261 aa)
LOC105498220Uncharacterized protein. (342 aa)
RO60Ro60, Y RNA binding protein. (538 aa)
TRAV22T cell receptor alpha variable 22. (147 aa)
C8BComplement C8 beta chain. (591 aa)
MACROH2A2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
C1SComplement C1s; Belongs to the peptidase S1 family. (596 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
ABCF2Uncharacterized protein. (618 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa)
C4AUncharacterized protein. (1744 aa)
ENSMNEP00000038649Ig-like domain-containing protein. (235 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (285 aa)
LOC105474413Ig-like domain-containing protein. (295 aa)
LOC105499692Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
MROH2BMaestro heat like repeat family member 2B. (1585 aa)
LOC105474426Ig-like domain-containing protein. (263 aa)
LOC105499748Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
ENSMNEP00000044636Histone H2A; Belongs to the histone H2A family. (102 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
ENSMNEP00000016015Uncharacterized protein. (433 aa)
CD86CD86 molecule. (329 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
ENSMNEP00000015048Histone domain-containing protein. (126 aa)
LOC105499746Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
ENSMNEP00000012828Histone H2B; Belongs to the histone H2B family. (129 aa)
C1RLComplement C1r subcomponent like. (433 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (268 aa)
ENSMNEP00000010506Ig-like domain-containing protein. (142 aa)
ENSMNEP00000010486Ig-like domain-containing protein. (133 aa)
LOC105476302Histone H3.3. (136 aa)
TRIM11Tripartite motif containing 11. (468 aa)
C8GComplement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (228 aa)
CD80CD80 molecule. (288 aa)
LOC105469173Histone H3; Belongs to the histone H3 family. (136 aa)
SSBSmall RNA binding exonuclease protection factor La. (363 aa)
LOC105482587Uncharacterized LOC105482587. (103 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC105482591Histone H2A type 1-B/E. (130 aa)
SNRPBSmall nuclear ribonucleoprotein polypeptides B and B1. (361 aa)
ENSMNEP00000006547annotation not available (103 aa)
TRIM21Tripartite motif containing 21. (475 aa)
H3C13H3 clustered histone 13. (136 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
LOC105482638-9Histone H3.1. (136 aa)
LOC105482638-8Histone H3.1. (136 aa)
LOC105482638-7Histone H3.1. (136 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (263 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105491648Histone H2A type 1. (130 aa)
LOC105499682Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSMNEP00000004997annotation not available (103 aa)
LOC105482586Histone H4. (103 aa)
LOC105482579-2Histone H2B type 1. (126 aa)
LOC105470433MHC class II antigen. (260 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
ENSMNEP00000004521Ig-like domain-containing protein. (230 aa)
LOC105491665Histone H4. (103 aa)
LOC105482638-6Histone H3.1. (136 aa)
PRTN3Proteinase 3; Belongs to the peptidase S1 family. (258 aa)
LOC105482573Histone H4. (103 aa)
LOC105482638-5Histone H3.1. (136 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSMNEP00000003706Histone H2B; Belongs to the histone H2B family. (136 aa)
LOC105482579Histone H2B type 1. (126 aa)
ENSMNEP00000003373Uncharacterized protein. (105 aa)
H2BC8Histone H2B type 1. (126 aa)
LOC105491642Histone H2A type 1. (130 aa)
H1-5Histone cluster 1 H1 family member b. (226 aa)
LOC105482638-4Histone H3.1. (136 aa)
C1QCComplement C1q C chain. (245 aa)
LOC105478976Histone H3; Belongs to the histone H3 family. (136 aa)
TRIM58Tripartite motif containing 58. (486 aa)
LOC105491667Histone H2A type 1. (130 aa)
LOC105497787Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC6Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC7Histone H2A; Belongs to the histone H2A family. (130 aa)
H2AWHistone H2A; Belongs to the histone H2A family. (130 aa)
LOC105478977Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC105482572Histone H3.1. (136 aa)
LOC105482571Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC105482560Histone domain-containing protein; Belongs to the histone H2B family. (127 aa)
H2AC14Histone H2A; Belongs to the histone H2A family. (128 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSMNEP00000002245Ig-like domain-containing protein. (232 aa)
H2AC12Histone H2A type 1-H. (128 aa)
CD40CD40 molecule. (278 aa)
ENSMNEP00000002194annotation not available (103 aa)
C5Complement C5. (1676 aa)
H2AC21Histone H2A; Belongs to the histone H2A family. (130 aa)
H1-4Histone cluster 1 H1 family member e. (219 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
LOC105491634Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105478980Histone H4. (103 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSMNEP00000001463annotation not available (103 aa)
C1RComplement C1r; Belongs to the peptidase S1 family. (690 aa)
LOC112422912Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSMNEP00000001351Ig-like domain-containing protein. (151 aa)
H2BC14Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105482638-3Histone H3.1. (136 aa)
ENSMNEP00000000889annotation not available (103 aa)
ENSMNEP00000000821Ig-like domain-containing protein. (143 aa)
LOC105466836Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
LOC105491644Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC105482638-2Histone H3.1. (136 aa)
LOC105491635Histone H2A; Belongs to the histone H2A family. (130 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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