STRINGSTRING
ITGA2 ITGA2 LOC105499514 LOC105499514 ITGA9 ITGA9 ACTL8 ACTL8 SLC8A1 SLC8A1 LMNA LMNA TGFB3 TGFB3 ENSMNEP00000041206 ENSMNEP00000041206 ITGA4 ITGA4 MYL3 MYL3 ITGA8 ITGA8 DAG1 DAG1 IL6 IL6 MYH4 MYH4 ENSMNEP00000001353 ENSMNEP00000001353 PRKAB2 PRKAB2 IGF1 IGF1 TNNT3 TNNT3 CACNA2D4 CACNA2D4 ACTG1 ACTG1 RYR2 RYR2 CACNA1F CACNA1F ACTL7B ACTL7B ITGAV ITGAV TNNT1 TNNT1 LRRC66 LRRC66 ITGB1 ITGB1 ACTRT1 ACTRT1 PRKAA2 PRKAA2 CACNA1S CACNA1S ENSMNEP00000006983 ENSMNEP00000006983 MYH1 MYH1 CACNA2D1 CACNA2D1 CACNG5 CACNG5 TTN TTN EDN1 EDN1 ACTC1 ACTC1 ITGB3 ITGB3 DMD DMD ENSMNEP00000008869 ENSMNEP00000008869 CACNB3 CACNB3 MYBPC3 MYBPC3 MYH15 MYH15 CACNG7 CACNG7 ITGA3 ITGA3 SGCD SGCD ITGB7 ITGB7 PRKAA1 PRKAA1 CACNG1 CACNG1 AGT AGT SGCB SGCB CACNB2 CACNB2 TNNC1 TNNC1 CACNA1C CACNA1C ACE ACE ENSMNEP00000013651 ENSMNEP00000013651 ITGA11 ITGA11 ENSMNEP00000014494 ENSMNEP00000014494 TPM1 TPM1 TPM2 TPM2 ATP2A2 ATP2A2 ENSMNEP00000016104 ENSMNEP00000016104 SLC8A2 SLC8A2 PRKAG1 PRKAG1 CACNG2 CACNG2 LAMA2 LAMA2 ITGB6 ITGB6 CACNB4 CACNB4 CACNA2D2 CACNA2D2 MYH3 MYH3 ACTB ACTB TPM3 TPM3 CACNG8 CACNG8 ENSMNEP00000021411 ENSMNEP00000021411 ENSMNEP00000022630 ENSMNEP00000022630 ITGA10 ITGA10 SGCG SGCG ITGA2B ITGA2B PRKAB1 PRKAB1 TNNI3 TNNI3 CACNG6 CACNG6 ITGA5 ITGA5 ITGB4 ITGB4 ITGB8 ITGB8 MYH8 MYH8 PRKAG3 PRKAG3 ENSMNEP00000028540 ENSMNEP00000028540 TNF TNF ACTL7A ACTL7A ACTRT2 ACTRT2 PRKAG2 PRKAG2 DES DES ATP2A1 ATP2A1 LAMA1 LAMA1 CACNG3 CACNG3 MYH6 MYH6 ITGA1 ITGA1 ENSMNEP00000033545 ENSMNEP00000033545 ITGA7 ITGA7 ENSMNEP00000034287 ENSMNEP00000034287 CACNG4 CACNG4 ITGA6 ITGA6 CACNA1D CACNA1D SLC8A3 SLC8A3 SGCA SGCA ENSMNEP00000035724 ENSMNEP00000035724 TNNT2 TNNT2 MYL2 MYL2 ENSMNEP00000037049 ENSMNEP00000037049 CACNB1 CACNB1 ATP2A3 ATP2A3 ENSMNEP00000038177 ENSMNEP00000038177 SLC39A12 SLC39A12 SPEGNB SPEGNB ENSMNEP00000039230 ENSMNEP00000039230 TGFB1 TGFB1 EMD EMD ITGB5 ITGB5 TGFB2 TGFB2 TPM4 TPM4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
LOC105499514Uncharacterized protein. (5591 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1027 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (663 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ENSMNEP00000041206Uncharacterized protein; Belongs to the actin family. (163 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
MYL3Myosin light chain 3. (227 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
DAG1Dystroglycan 1. (894 aa)
IL6Interleukin 6. (214 aa)
MYH4Myosin heavy chain 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
ENSMNEP00000001353Uncharacterized protein; Belongs to the tropomyosin family. (241 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
IGF1Insulin like growth factor 1. (208 aa)
TNNT3Troponin T3, fast skeletal type. (261 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1116 aa)
ACTG1Actin gamma 1. (377 aa)
RYR2Ryanodine receptor 2. (4951 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1960 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1017 aa)
TNNT1Troponin T1, slow skeletal type. (234 aa)
LRRC66Leucine rich repeat containing 66. (820 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1867 aa)
ENSMNEP00000006983Uncharacterized protein. (988 aa)
MYH1Myosin heavy chain 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
TTNTitin. (22498 aa)
EDN1Endothelin 1. (211 aa)
ACTC1Actin alpha cardiac muscle 1. (385 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
DMDDystrophin. (3685 aa)
ENSMNEP00000008869Uncharacterized protein; Belongs to the tropomyosin family. (231 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
MYBPC3Myosin binding protein C, cardiac. (1276 aa)
MYH15Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1971 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (246 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
SGCDSarcoglycan delta. (290 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
SGCBSarcoglycan beta. (319 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
ACEAngiotensin-converting enzyme. (1160 aa)
ENSMNEP00000013651Uncharacterized protein. (568 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1213 aa)
ENSMNEP00000014494Uncharacterized protein; Belongs to the tropomyosin family. (228 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (326 aa)
TPM2Tropomyosin 2; Belongs to the tropomyosin family. (322 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
ENSMNEP00000016104Uncharacterized protein. (57 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
LAMA2Laminin subunit alpha 2. (3122 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1153 aa)
MYH3Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
ACTBActin beta. (379 aa)
TPM3Tropomyosin 3; Belongs to the tropomyosin family. (285 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (413 aa)
ENSMNEP00000021411Uncharacterized protein; Belongs to the tropomyosin family. (231 aa)
ENSMNEP00000022630VGCC_alpha2 domain-containing protein. (175 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1168 aa)
SGCGSarcoglycan gamma. (291 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (236 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
ITGB4Integrin beta. (1823 aa)
ITGB8Integrin beta. (421 aa)
MYH8Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
ENSMNEP00000028540Uncharacterized protein. (139 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (377 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa)
DESDesmin; Belongs to the intermediate filament family. (470 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1030 aa)
LAMA1Laminin subunit alpha 1. (3079 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
ENSMNEP00000033545Uncharacterized protein. (200 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
ENSMNEP00000034287Calponin-homology (CH) domain-containing protein. (406 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (339 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2209 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
SGCASarcoglycan alpha. (387 aa)
ENSMNEP00000035724Uncharacterized protein. (437 aa)
TNNT2Troponin T2, cardiac type. (302 aa)
MYL2Myosin light chain 2. (166 aa)
ENSMNEP00000037049Uncharacterized protein. (188 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (643 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1037 aa)
ENSMNEP00000038177Uncharacterized protein; Belongs to the actin family. (156 aa)
SLC39A12Solute carrier family 39 member 12. (691 aa)
SPEGNBSPEG neighbor. (238 aa)
ENSMNEP00000039230Uncharacterized protein. (210 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
EMDEmerin. (258 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TPM4Tropomyosin 4. (239 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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