STRINGSTRING
ENSMNEP00000041206 ENSMNEP00000041206 LMNA LMNA CTNNA2 CTNNA2 SLC8A1 SLC8A1 ACTL8 ACTL8 ITGA9 ITGA9 TCF7L1 TCF7L1 ACTN2 ACTN2 ITGA2 ITGA2 ACTN3 ACTN3 TCF7 TCF7 ITGA8 ITGA8 DAG1 DAG1 CTNNB1 CTNNB1 CACNA2D4 CACNA2D4 ACTG1 ACTG1 RYR2 RYR2 PLEC PLEC CACNA1F CACNA1F ACTL7B ACTL7B ITGAV ITGAV DSC3 DSC3 LRRC66 LRRC66 ITGB1 ITGB1 ACTRT1 ACTRT1 CACNA1S CACNA1S DSC2 DSC2 ENSMNEP00000006983 ENSMNEP00000006983 CACNA2D1 CACNA2D1 CACNG5 CACNG5 ITGB3 ITGB3 DMD DMD CACNB3 CACNB3 DSG2 DSG2 CACNG7 CACNG7 ITGA3 ITGA3 SGCD SGCD ITGB7 ITGB7 PKP2 PKP2 CACNG1 CACNG1 SGCB SGCB CACNB2 CACNB2 CACNA1C CACNA1C ITGA11 ITGA11 ATP2A2 ATP2A2 SLC8A2 SLC8A2 CACNG2 CACNG2 LAMA2 LAMA2 ITGB6 ITGB6 CACNB4 CACNB4 CACNA2D2 CACNA2D2 ACTB ACTB CACNG8 CACNG8 ENSMNEP00000022630 ENSMNEP00000022630 ITGA10 ITGA10 SGCG SGCG DSC1 DSC1 ITGA2B ITGA2B JUP JUP CACNG6 CACNG6 ITGA5 ITGA5 ITGB4 ITGB4 ITGB8 ITGB8 ENSMNEP00000028540 ENSMNEP00000028540 ACTL7A ACTL7A ACTRT2 ACTRT2 DES DES ATP2A1 ATP2A1 LAMA1 LAMA1 CACNG3 CACNG3 TCF7L2 TCF7L2 ITGA1 ITGA1 ITGA7 ITGA7 ENSMNEP00000034287 ENSMNEP00000034287 DSP DSP CACNG4 CACNG4 ITGA6 ITGA6 CACNA1D CACNA1D SLC8A3 SLC8A3 SGCA SGCA CTNNA3 CTNNA3 ENSMNEP00000035724 ENSMNEP00000035724 CACNB1 CACNB1 ATP2A3 ATP2A3 DSG3 DSG3 ENSMNEP00000038177 ENSMNEP00000038177 ENSMNEP00000038522 ENSMNEP00000038522 SLC39A12 SLC39A12 EMD EMD ITGB5 ITGB5 CTNNA1 CTNNA1 CDH2 CDH2 LEF1 LEF1 ITGA4 ITGA4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000041206Uncharacterized protein; Belongs to the actin family. (163 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (663 aa)
CTNNA2Catenin alpha 2. (953 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1027 aa)
TCF7L1Transcription factor 7 like 1. (589 aa)
ACTN2Actinin alpha 2. (894 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (929 aa)
TCF7Transcription factor 7. (496 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
DAG1Dystroglycan 1. (894 aa)
CTNNB1Catenin beta 1. (781 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1116 aa)
ACTG1Actin gamma 1. (377 aa)
RYR2Ryanodine receptor 2. (4951 aa)
PLECPlectin. (4774 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1960 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1017 aa)
DSC3Desmocollin 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (896 aa)
LRRC66Leucine rich repeat containing 66. (820 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1867 aa)
DSC2Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (901 aa)
ENSMNEP00000006983Uncharacterized protein. (988 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
DMDDystrophin. (3685 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
DSG2Desmoglein 2. (1118 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (246 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
SGCDSarcoglycan delta. (290 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
PKP2Plakophilin 2. (869 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
SGCBSarcoglycan beta. (319 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1213 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
LAMA2Laminin subunit alpha 2. (3122 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1153 aa)
ACTBActin beta. (379 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (413 aa)
ENSMNEP00000022630VGCC_alpha2 domain-containing protein. (175 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1168 aa)
SGCGSarcoglycan gamma. (291 aa)
DSC1Desmocollin 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (894 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)
JUPJunction plakoglobin. (745 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (236 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
ITGB4Integrin beta. (1823 aa)
ITGB8Integrin beta. (421 aa)
ENSMNEP00000028540Uncharacterized protein. (139 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (377 aa)
DESDesmin; Belongs to the intermediate filament family. (470 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1030 aa)
LAMA1Laminin subunit alpha 1. (3079 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
TCF7L2Transcription factor 7 like 2. (523 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
ENSMNEP00000034287Calponin-homology (CH) domain-containing protein. (406 aa)
DSPDesmoplakin. (2272 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (339 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2209 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
SGCASarcoglycan alpha. (387 aa)
CTNNA3Catenin alpha 3. (895 aa)
ENSMNEP00000035724Uncharacterized protein. (437 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (643 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1037 aa)
DSG3Desmoglein 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (999 aa)
ENSMNEP00000038177Uncharacterized protein; Belongs to the actin family. (156 aa)
ENSMNEP00000038522Uncharacterized protein. (795 aa)
SLC39A12Solute carrier family 39 member 12. (691 aa)
EMDEmerin. (258 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
CTNNA1Catenin alpha 1. (906 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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