STRINGSTRING
PDHX PDHX GCDH GCDH LOC103877626 LOC103877626 DDO DDO URB2 URB2 NIT2 NIT2 IDH1 IDH1 ME3 ME3 LDHAL6A LDHAL6A BCKDHB BCKDHB GPT GPT TXNRD1 TXNRD1 ME2 ME2 DBT DBT FH FH PDK3 PDK3 TXNRD2 TXNRD2 LDHC LDHC DLAT DLAT PDHA2 PDHA2 MDH2 MDH2 PC PC DLD DLD SUCLA2 SUCLA2 GOT2 GOT2 IDH3A IDH3A LDHB LDHB DLST DLST ENSPANP00000015767 ENSPANP00000015767 LDHD LDHD SUCLG1 SUCLG1 ME1 ME1 TXNRD3 TXNRD3 PDK1 PDK1 ACO1 ACO1 DHTKD1 DHTKD1 PDK2 PDK2 NAGS NAGS GOT1 GOT1 ENSPANP00000023548 ENSPANP00000023548 PKLR PKLR ACO2 ACO2 CS CS ENSPANP00000026478 ENSPANP00000026478 ENSPANP00000027331 ENSPANP00000027331 ENSPANP00000028586 ENSPANP00000028586 PCK2 PCK2 ENSPANP00000030120 ENSPANP00000030120 ENSPANP00000030533 ENSPANP00000030533 OGDHL OGDHL IDH3G IDH3G ENSPANP00000032642 ENSPANP00000032642 OGDH OGDH BCKDHA BCKDHA ENO4 ENO4 IDH3B IDH3B ENSPANP00000035148 ENSPANP00000035148 PDHB PDHB GLUD2 GLUD2 GOT1L1 GOT1L1 ENSPANP00000039351 ENSPANP00000039351 PCK1 PCK1 ENSPANP00000040663 ENSPANP00000040663 ENSPANP00000042471 ENSPANP00000042471 PDHA1 PDHA1 MDH1 MDH1 ENSPANP00000045671 ENSPANP00000045671 ENSPANP00000046288 ENSPANP00000046288 IDH2 IDH2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (501 aa)
GCDHGlutaryl-CoA dehydrogenase. (438 aa)
LOC103877626L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (360 aa)
DDOD-aspartate oxidase. (381 aa)
URB2URB2 ribosome biogenesis homolog. (1483 aa)
NIT2Nitrilase family member 2. (326 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
ME3Malic enzyme. (604 aa)
LDHAL6AL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (392 aa)
GPTGlutamic--pyruvic transaminase. (496 aa)
TXNRD1Thioredoxin reductase 1. (648 aa)
ME2Malic enzyme. (584 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (482 aa)
FHFumarate hydratase. (542 aa)
PDK3Protein-serine/threonine kinase. (415 aa)
TXNRD2Thioredoxin reductase 2. (523 aa)
LDHCL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
PDHA2Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (388 aa)
MDH2Malate dehydrogenase. (338 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1179 aa)
DLDDihydrolipoyl dehydrogenase. (515 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (463 aa)
GOT2Aspartate aminotransferase. (430 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
DLSTDihydrolipoamide S-succinyltransferase. (454 aa)
ENSPANP00000015767L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
LDHDLactate dehydrogenase D. (484 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (346 aa)
ME1Malic enzyme. (572 aa)
TXNRD3Thioredoxin reductase 3. (598 aa)
PDK1Protein-serine/threonine kinase. (436 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (889 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (919 aa)
PDK2Protein-serine/threonine kinase. (616 aa)
NAGSN-acetylglutamate synthase. (534 aa)
GOT1Aspartate aminotransferase. (413 aa)
ENSPANP00000023548L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (272 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (891 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
ENSPANP00000026478Uncharacterized protein; Belongs to the LDH/MDH superfamily. (337 aa)
ENSPANP00000027331Pyruvate kinase; Belongs to the pyruvate kinase family. (386 aa)
ENSPANP00000028586Uncharacterized protein. (101 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (645 aa)
ENSPANP00000030120Uncharacterized protein. (488 aa)
ENSPANP00000030533E1_dh domain-containing protein. (377 aa)
OGDHLOxoglutarate dehydrogenase like. (1043 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (404 aa)
ENSPANP00000032642Peripheral subunit-binding (PSBD) domain-containing protein. (560 aa)
OGDHOxoglutarate dehydrogenase. (1038 aa)
BCKDHA2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (448 aa)
ENO4Enolase 4. (627 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (383 aa)
ENSPANP00000035148Uncharacterized protein; Belongs to the LDH/MDH superfamily. (396 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
GLUD2ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (541 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (401 aa)
ENSPANP00000039351L-lactate dehydrogenase. (239 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
ENSPANP00000040663Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (443 aa)
ENSPANP00000042471ELFV_dehydrog domain-containing protein. (174 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (469 aa)
MDH1Malate dehydrogenase. (352 aa)
ENSPANP00000045671Uncharacterized protein. (321 aa)
ENSPANP00000046288Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (374 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.