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| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | SHC2 | Uncharacterized protein. (567 aa) |
| | GAB2 | GRB2 associated binding protein 2. (674 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa) |
| | SOCS4 | Suppressor of cytokine signaling 4. (440 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (796 aa) |
| | CBLB | Cbl proto-oncogene B. (982 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (853 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1224 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | DOK1 | Docking protein 1. (474 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) |
| | EFNA3 | Ephrin A3; Belongs to the ephrin family. (238 aa) |
| | EPHB1 | EPH receptor B1. (984 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) |
| | FGF21 | Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family. (174 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (278 aa) |
| | IGF2 | IlGF domain-containing protein. (245 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | KLB | Klotho beta. (1044 aa) |
| | EPHA2 | EPH receptor A2. (976 aa) |
| | CBL | Cbl proto-oncogene. (918 aa) |
| | EFNB1 | Ephrin B1; Belongs to the ephrin family. (346 aa) |
| | TIE1 | Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa) |
| | ENSPANP00000005238 | Uncharacterized protein. (547 aa) |
| | PDGFD | Platelet derived growth factor D. (303 aa) |
| | PDGFRL | Platelet derived growth factor receptor like. (376 aa) |
| | EPHA4 | EPH receptor A4. (986 aa) |
| | EPHA8 | EPH receptor A8. (1005 aa) |
| | EPHA3 | EPH receptor A3. (984 aa) |
| | EPGN | Epithelial mitogen. (154 aa) |
| | ANGPT1 | Angiopoietin 1. (498 aa) |
| | NTF4 | Neurotrophin 4; Belongs to the NGF-beta family. (210 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1325 aa) |
| | GRB10 | Growth factor receptor bound protein 10. (593 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (338 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (802 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (522 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1382 aa) |
| | EPHB4 | EPH receptor B4. (987 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1161 aa) |
| | RTN4RL1 | Reticulon 4 receptor like 1. (441 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (205 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa) |
| | SPRY3 | Sprouty RTK signaling antagonist 3. (288 aa) |
| | CBLC | Cbl proto-oncogene C. (465 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (975 aa) |
| | EPHB6 | EPH receptor B6. (1019 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa) |
| | KL | Klotho. (1012 aa) |
| | INSRR | Tyrosine-protein kinase receptor. (1301 aa) |
| | EPHA7 | EPH receptor A7. (998 aa) |
| | FRS3 | Fibroblast growth factor receptor substrate 3 (Predicted). (492 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (412 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | NRG4 | Neuregulin 4. (115 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (465 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1315 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa) |
| | NGEF | Neuronal guanine nucleotide exchange factor. (712 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | BCR | BCR activator of RhoGEF and GTPase. (1083 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | EREG | Epiregulin. (169 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | ANGPT4 | Angiopoietin 4. (503 aa) |
| | EPHB2 | EPH receptor B2. (1085 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa) |
| | ANGPT2 | Angiopoietin 2. (496 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa) |
| | EPHA1 | EPH receptor A1. (976 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (555 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) |
| | TEK | TEK receptor tyrosine kinase. (1124 aa) |
| | SH3GL2 | SH3 domain containing GRB2 like 2, endophilin A1. (358 aa) |
| | SHC3 | SHC adaptor protein 3. (598 aa) |
| | RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1. (557 aa) |
| | FGF11 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa) |
| | EFNB3 | Ephrin B3; Belongs to the ephrin family. (340 aa) |
| | GRAP | GRB2 related adaptor protein. (217 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | ENSPANP00000021036 | NGF domain-containing protein; Belongs to the NGF-beta family. (197 aa) |
| | IRS2 | Insulin receptor substrate 2. (1316 aa) |
| | SORT1 | Sortilin. (864 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (840 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | SORCS2 | Sortilin related VPS10 domain containing receptor 2. (1160 aa) |
| | NRG2 | Neuregulin 2. (851 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (775 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | ENSPANP00000028630 | Uncharacterized protein. (441 aa) |
| | NTRK3 | Tyrosine-protein kinase receptor. (864 aa) |
| | ENSPANP00000030056 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (384 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1404 aa) |
| | NRG1 | Neuregulin 1. (713 aa) |
| | SH3GL3 | SH3 domain containing GRB2 like 3, endophilin A3. (354 aa) |
| | GAB1 | GRB2 associated binding protein 1. (790 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (995 aa) |
| | ENSPANP00000033846 | Uncharacterized protein. (542 aa) |
| | ABL1 | Tyrosine-protein kinase. (1112 aa) |
| | EPHB3 | EPH receptor B3. (1008 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (838 aa) |
| | ABL2 | Tyrosine-protein kinase. (1182 aa) |
| | SHC1 | SHC adaptor protein 1. (601 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | TGFA | Transforming growth factor alpha. (166 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1362 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1350 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1399 aa) |
| | IGF1 | Insulin like growth factor 1. (208 aa) |
| | EPHA5 | EPH receptor A5. (1038 aa) |
| | EPHA10 | EPH receptor A10. (1017 aa) |
| | PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (184 aa) |
| | NGFR | Nerve growth factor receptor. (429 aa) |
| | EFNA2 | Ephrin A2; Belongs to the ephrin family. (213 aa) |
| | SH3KBP1 | SH3 domain containing kinase binding protein 1. (690 aa) |
| | IL34 | Interleukin 34. (242 aa) |
| | AREG | Amphiregulin. (274 aa) |
| | BTC | Betacellulin. (178 aa) |
| | EFNA4 | Ephrin A4; Belongs to the ephrin family. (206 aa) |
| | BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (312 aa) |
| | SH3GL1 | SH3 domain containing GRB2 like 1, endophilin A2. (365 aa) |
| | EFNB2 | Ephrin B2; Belongs to the ephrin family. (334 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | NRG3 | Neuregulin 3. (719 aa) |
| | NGF | Nerve growth factor; Belongs to the NGF-beta family. (123 aa) |
