STRINGSTRING
MAML1 MAML1 APP APP MAML3 MAML3 MAML2 MAML2 PSEN2 PSEN2 DLL3 DLL3 HES1 HES1 DTX1 DTX1 PLD3 PLD3 DTX3L DTX3L HEY1 HEY1 DTX4 DTX4 NRARP NRARP NOTCH2 NOTCH2 APLP2 APLP2 APBB2 APBB2 DLL1 DLL1 DTX3 DTX3 NELL2 NELL2 HEYL HEYL NECAB1 NECAB1 NLRP4 NLRP4 HLX HLX APH1A APH1A NOTCH3 NOTCH3 HES3 HES3 CAPN13 CAPN13 GPSM3 GPSM3 NOTCH4 NOTCH4 ADAM17 ADAM17 TNFRSF21 TNFRSF21 MFNG MFNG JAG2 JAG2 ADAM10 ADAM10 APH1B APH1B ROBO3 ROBO3 NOTCH1 NOTCH1 DTX2 DTX2 RFNG RFNG NECAB3 NECAB3 JAG1 JAG1 HES2 HES2 RBPJL RBPJL PODXL2 PODXL2 HES4 HES4 HES7 HES7 PITRM1 PITRM1 APBB1 APBB1 APLP1 APLP1 NELL1 NELL1 NECAB2 NECAB2 RHBDF1 RHBDF1 RBPJ RBPJ TRIM38 TRIM38 HES5 HES5 CADPS2 CADPS2 LFNG LFNG FAT3 FAT3 HES6 HES6 EYS EYS DLL4 DLL4 HEY2 HEY2 PSEN1 PSEN1 NCSTN NCSTN AKAP9 AKAP9 PTPRO PTPRO SYT11 SYT11 SEZ6 SEZ6 UNC5C UNC5C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAML1Mastermind like transcriptional coactivator 1. (1016 aa)
APPAmyloid beta precursor protein. (770 aa)
MAML3Mastermind like transcriptional coactivator 3. (1135 aa)
MAML2Mastermind like transcriptional coactivator 2. (1156 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
DLL3Delta like canonical Notch ligand 3. (618 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
DTX1Deltex E3 ubiquitin ligase 1. (622 aa)
PLD3Phospholipase D family member 3. (490 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (740 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
DTX4Deltex E3 ubiquitin ligase 4. (619 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
NOTCH2Notch receptor 2. (2603 aa)
APLP2Amyloid beta precursor like protein 2. (763 aa)
APBB2Amyloid beta precursor protein binding family B member 2. (759 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
DTX3Deltex E3 ubiquitin ligase 3. (350 aa)
NELL2Neural EGFL like 2. (816 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
NECAB1N-terminal EF-hand calcium binding protein 1. (352 aa)
NLRP4NLR family pyrin domain containing 4. (994 aa)
HLXH2.0 like homeobox. (494 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
NOTCH3Notch receptor 3. (2315 aa)
HES3Hes family bHLH transcription factor 3. (185 aa)
CAPN13Calpain 13; Belongs to the peptidase C2 family. (669 aa)
GPSM3G protein signaling modulator 3. (160 aa)
NOTCH4Notch receptor 4. (2000 aa)
ADAM17ADAM metallopeptidase domain 17. (1005 aa)
TNFRSF21TNF receptor superfamily member 21. (655 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (321 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1213 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
ROBO3Roundabout guidance receptor 3. (1384 aa)
NOTCH1Notch receptor 1. (2541 aa)
DTX2Deltex E3 ubiquitin ligase 2. (622 aa)
RFNGBeta-1,3-N-acetylglucosaminyltransferase. (331 aa)
NECAB3N-terminal EF-hand calcium binding protein 3. (396 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1190 aa)
HES2Hes family bHLH transcription factor 2. (173 aa)
RBPJLRecombination signal binding protein for immunoglobulin kappa J region like. (509 aa)
PODXL2Podocalyxin like 2. (608 aa)
HES4Hes family bHLH transcription factor 4. (221 aa)
HES7Hes family bHLH transcription factor 7. (230 aa)
PITRM1Pitrilysin metallopeptidase 1. (1038 aa)
APBB1Amyloid beta precursor protein binding family B member 1. (738 aa)
APLP1Amyloid beta precursor like protein 1. (660 aa)
NELL1Neural EGFL like 1. (838 aa)
NECAB2N-terminal EF-hand calcium binding protein 2. (378 aa)
RHBDF1Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. (855 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (529 aa)
TRIM38Tripartite motif containing 38. (468 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
CADPS2Calcium dependent secretion activator 2. (1297 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (379 aa)
FAT3FAT atypical cadherin 3. (4557 aa)
HES6Hes family bHLH transcription factor 6. (180 aa)
EYSEyes shut homolog. (3164 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (713 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (326 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (452 aa)
NCSTNNicastrin. (721 aa)
AKAP9A-kinase anchoring protein 9. (3922 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
SYT11Synaptotagmin 11. (431 aa)
SEZ6Seizure related 6 homolog. (995 aa)
UNC5CUnc-5 netrin receptor C. (931 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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