STRINGSTRING
GREM2 GREM2 SMAD5 SMAD5 BMP8B BMP8B LTBP1 LTBP1 NOG NOG ACVR1C ACVR1C FST FST GDF11 GDF11 GDF6 GDF6 TGFB1 TGFB1 TGFB2 TGFB2 SMAD7 SMAD7 BMPR2 BMPR2 HJV HJV TGFBR2 TGFBR2 CHRD CHRD SMAD4 SMAD4 ZFYVE9 ZFYVE9 INHA INHA BMP10 BMP10 INHBC INHBC AMH AMH BMP6 BMP6 SMAD3 SMAD3 BMP7 BMP7 SKI SKI SKIL SKIL GDF7 GDF7 SMAD1 SMAD1 INHBA INHBA ACVR1B ACVR1B TGFB3 TGFB3 ACVR2A ACVR2A BMP4 BMP4 SMURF1 SMURF1 BAMBI BAMBI BMPR1B BMPR1B ZFYVE16 ZFYVE16 GDF2 GDF2 ACVR1 ACVR1 AMHR2 AMHR2 ENSPANP00000024775 ENSPANP00000024775 ACVR2B ACVR2B SMAD9 SMAD9 SMURF2 SMURF2 INHBB INHBB BMP5 BMP5 ENG ENG SMAD2 SMAD2 ACVRL1 ACVRL1 BMP2 BMP2 INHBE INHBE BMPR1A BMPR1A SMAD6 SMAD6 TGFBR1 TGFBR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GREM2Gremlin. (168 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
BMP8BTGF_BETA_2 domain-containing protein. (402 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1720 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
FSTFollistatin. (344 aa)
GDF11Growth differentiation factor 11. (406 aa)
GDF6Growth differentiation factor 6. (455 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SMAD7Mothers against decapentaplegic homolog. (493 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
HJVHemojuvelin BMP co-receptor. (426 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (955 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1423 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
INHBCInhibin subunit beta C. (352 aa)
AMHAnti-Mullerian hormone. (560 aa)
BMP6Bone morphogenetic protein 6. (515 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
SKISKI proto-oncogene. (700 aa)
SKILSKI like proto-oncogene. (684 aa)
GDF7Growth differentiation factor 7. (447 aa)
SMAD1Mothers against decapentaplegic homolog. (498 aa)
INHBAInhibin subunit beta A. (426 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
BMP4Bone morphogenetic protein 4, isoform 3 (Predicted). (408 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ZFYVE16Zinc finger FYVE domain-containing protein. (1530 aa)
GDF2Growth differentiation factor 2. (429 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
AMHR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (480 aa)
ENSPANP00000024775Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (468 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
SMAD9Mothers against decapentaplegic homolog. (512 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (682 aa)
INHBBInhibin subunit beta B. (407 aa)
BMP5Bone morphogenetic protein 5. (471 aa)
ENGZP domain-containing protein. (274 aa)
SMAD2Mothers against decapentaplegic homolog. (472 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (500 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
INHBEInhibin subunit beta E. (351 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SMAD6Mothers against decapentaplegic homolog. (481 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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