STRINGSTRING
SMAD5 SMAD5 LTBP1 LTBP1 TGFB1 TGFB1 TGFB2 TGFB2 SMAD7 SMAD7 TGFBR2 TGFBR2 SMAD4 SMAD4 ZFYVE9 ZFYVE9 SMAD3 SMAD3 SKI SKI SKIL SKIL SMAD1 SMAD1 TGFB3 TGFB3 SMURF1 SMURF1 BAMBI BAMBI ZFYVE16 ZFYVE16 SMAD9 SMAD9 SMURF2 SMURF2 SMAD2 SMAD2 SMAD6 SMAD6 TGFBR1 TGFBR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD5Mothers against decapentaplegic homolog. (465 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1720 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SMAD7Mothers against decapentaplegic homolog. (493 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1423 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
SKISKI proto-oncogene. (700 aa)
SKILSKI like proto-oncogene. (684 aa)
SMAD1Mothers against decapentaplegic homolog. (498 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
ZFYVE16Zinc finger FYVE domain-containing protein. (1530 aa)
SMAD9Mothers against decapentaplegic homolog. (512 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (682 aa)
SMAD2Mothers against decapentaplegic homolog. (472 aa)
SMAD6Mothers against decapentaplegic homolog. (481 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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