Your Input: | |
| | SMARCE1 | HMG box domain-containing protein. (414 aa) |
| | CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1067 aa) |
| | ARID5B | AT-rich interaction domain 5B. (1205 aa) |
| | ENSPANP00000036835 | Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (432 aa) |
| | YAP1 | Yes associated protein 1. (506 aa) |
| | TRIM28 | Tripartite motif containing 28. (818 aa) |
| | MED12L | Mediator complex subunit 12L. (2145 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1677 aa) |
| | ENY2 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa) |
| | MTA2 | Metastasis associated 1 family member 2. (673 aa) |
| | PRDM16 | PR/SET domain 16. (1186 aa) |
| | NUP98 | Nucleoporin 98. (1722 aa) |
| | TRIM37 | Tripartite motif containing 37. (963 aa) |
| | BRD8 | Bromodomain containing 8. (1243 aa) |
| | TRIM62 | Tripartite motif containing 62. (463 aa) |
| | RAP2C | RAP2C, member of RAS oncogene family. (183 aa) |
| | ENSPANP00000038891 | Uncharacterized protein. (304 aa) |
| | ARRB1 | Arrestin beta 1. (436 aa) |
| | ENSPANP00000039676 | Uncharacterized protein. (184 aa) |
| | ENSPANP00000039794 | Uncharacterized protein. (150 aa) |
| | MID2 | Midline 2. (732 aa) |
| | BRD4 | Bromodomain containing 4. (1344 aa) |
| | MED26 | TFIIS N-terminal domain-containing protein. (600 aa) |
| | SUPT7L | SPT7 like, STAGA complex gamma subunit. (414 aa) |
| | TADA2B | Transcriptional adapter. (420 aa) |
| | CIITA | Class II major histocompatibility complex transactivator. (1131 aa) |
| | ENSPANP00000041468 | Uncharacterized protein. (544 aa) |
| | MAGED1 | MAGE family member D1. (834 aa) |
| | CAMTA2 | Calmodulin binding transcription activator 2. (1241 aa) |
| | UBE3A | Ubiquitin protein ligase E3A. (788 aa) |
| | DCAF6 | DDB1 and CUL4 associated factor 6. (951 aa) |
| | ENSPANP00000042702 | PC4 domain-containing protein. (124 aa) |
| | TAF12 | TATA-box binding protein associated factor 12. (214 aa) |
| | ENSPANP00000043411 | Uncharacterized protein. (233 aa) |
| | NCOA1 | Nuclear receptor coactivator. (1399 aa) |
| | ENY2-2 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (91 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1551 aa) |
| | ENSPANP00000044332 | Uncharacterized protein. (242 aa) |
| | KAT8 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (467 aa) |
| | ZFPM2 | Zinc finger protein, FOG family member 2. (1151 aa) |
| | ENSPANP00000044744 | Uncharacterized protein. (167 aa) |
| | MYOCD | Myocardin. (984 aa) |
| | TRERF1 | Transcriptional regulating factor 1. (1227 aa) |
| | ENSPANP00000044994 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | CTBP2 | C-terminal binding protein 2. (985 aa) |
| | ZIC3 | Zic family member 3. (466 aa) |
| | YAF2 | YY1 associated factor 2. (204 aa) |
| | LMO4 | LIM domain only 4. (165 aa) |
| | MTDH | Metadherin. (612 aa) |
| | ENSPANP00000046189 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | CNOT9 | CCR4-NOT transcription complex subunit 9. (332 aa) |
| | ENSPANP00000046380 | Uncharacterized protein. (232 aa) |
| | ENSPANP00000046524 | PC4 domain-containing protein. (120 aa) |
| | ENY2-3 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (96 aa) |
| | SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1341 aa) |
| | ENSPANP00000047622 | Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (384 aa) |
| | ENSPANP00000000945 | Uncharacterized protein. (301 aa) |
| | MED12 | Mediator complex subunit 12. (2178 aa) |
| | MAML1 | Mastermind like transcriptional coactivator 1. (1016 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | RBM14 | RNA binding motif protein 14. (669 aa) |
| | NIBAN1 | Niban apoptosis regulator 1. (928 aa) |
| | RNF14 | RBR-type E3 ubiquitin transferase. (474 aa) |
| | PPARGC1B | PPARG coactivator 1 beta. (1023 aa) |
| | ENSPANP00000001905 | PC4 domain-containing protein. (131 aa) |
| | MAML3 | Mastermind like transcriptional coactivator 3. (1135 aa) |
| | MAML2 | Mastermind like transcriptional coactivator 2. (1156 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | PMF1 | Polyamine modulated factor 1. (205 aa) |
| | SS18 | SS18 subunit of BAF chromatin remodeling complex. (418 aa) |
| | PAGE1 | PAGE family member 1. (144 aa) |
| | PER2 | Period circadian regulator 2. (1280 aa) |
| | TAF5L | TATA-box binding protein associated factor 5 like. (589 aa) |
| | BCL3 | BCL3 transcription coactivator. (454 aa) |
| | DYRK1B | Dual specificity tyrosine phosphorylation regulated kinase 1B. (689 aa) |
| | MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (300 aa) |
| | SS18L2 | SS18 like 2. (77 aa) |
| | TADA3 | Transcriptional adaptor 3. (440 aa) |
| | WWC1 | WW and C2 domain containing 1. (1117 aa) |
| | DTX1 | Deltex E3 ubiquitin ligase 1. (622 aa) |
| | RNF4 | Ring finger protein 4. (190 aa) |
| | THRAP3 | Thyroid hormone receptor associated protein 3. (955 aa) |
| | AIP | Peptidylprolyl isomerase. (330 aa) |
| | ATN1 | Atrophin 1. (1190 aa) |
| | CCDC62 | Coiled-coil domain containing 62. (683 aa) |
| | JADE1 | Jade family PHD finger 1. (843 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | ENSPANP00000004936 | PC4 domain-containing protein. (140 aa) |
| | XPC | XPC complex subunit, DNA damage recognition and repair factor. (939 aa) |
| | VGLL1 | Vestigial like family member 1. (258 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | BCL9L | BCL9 like. (1500 aa) |
| | TRIM5 | Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (497 aa) |
| | FIZ1 | FLT3 interacting zinc finger 1. (496 aa) |
| | NFKBIB | NFKB inhibitor beta. (356 aa) |
| | USP21 | Ubiquitin specific peptidase 21; Belongs to the peptidase C19 family. (563 aa) |
| | KMT2C | Lysine methyltransferase 2C. (4887 aa) |
| | BCL10 | BCL10 immune signaling adaptor. (311 aa) |
| | TACC1 | Transforming acidic coiled-coil containing protein 1. (806 aa) |
| | MTA3 | Metastasis associated 1 family member 3. (594 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1468 aa) |
| | BUD31 | BUD31 homolog. (144 aa) |
| | WWOX | WW domain containing oxidoreductase. (414 aa) |
| | ZBED1 | Zinc finger BED-type containing 1. (694 aa) |
| | KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2003 aa) |
| | CARM1 | Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (608 aa) |
| | MED14 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa) |
| | HYAL2 | Hyaluronidase. (473 aa) |
| | CALCOCO1 | Calcium binding and coiled-coil domain 1. (691 aa) |
| | MYSM1 | Myb like, SWIRM and MPN domains 1. (877 aa) |
| | ENSPANP00000008217 | Nucleoplasmin domain-containing protein. (283 aa) |
| | SUB1 | PC4 domain-containing protein. (134 aa) |
| | KDM5A | Lysine demethylase 5A. (1692 aa) |
| | BCL9 | BCL9 transcription coactivator. (1426 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | LPIN2 | Lipin 2. (933 aa) |
| | DOT1L | Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1562 aa) |
| | TMF1 | TATA element modulatory factor 1. (1092 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1197 aa) |
| | USP16 | Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. (826 aa) |
| | TRIM22 | Uncharacterized protein. (480 aa) |
| | HCFC1 | Uncharacterized protein. (2083 aa) |
| | ENSPANP00000009676 | Uncharacterized protein. (179 aa) |
| | TRIM21 | Tripartite motif containing 21. (468 aa) |
| | MPND | MPN domain containing. (324 aa) |
| | CCDC124 | Coiled-coil domain containing 124. (223 aa) |
| | CNOT6 | CCR4-NOT transcription complex subunit 6. (557 aa) |
| | NCOA7 | Nuclear receptor coactivator 7. (942 aa) |
| | NPAT | Nuclear protein, coactivator of histone transcription. (1418 aa) |
| | COPS5 | COP9 signalosome subunit 5. (334 aa) |
| | ELK1 | ETS domain-containing protein. (428 aa) |
| | CEBPZ | CCAAT enhancer binding protein zeta. (1053 aa) |
| | MED30 | Mediator complex subunit 30. (178 aa) |
| | TAF6L | TATA-box binding protein associated factor 6 like. (731 aa) |
| | PBXIP1 | PBX homeobox interacting protein 1. (739 aa) |
| | TRIM32 | Tripartite motif containing 32. (653 aa) |
| | SERTAD2 | SERTA domain containing 2. (314 aa) |
| | MED16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (877 aa) |
| | ZMIZ2 | Zinc finger MIZ-type containing 2. (920 aa) |
| | TRIM24 | Tripartite motif containing 24. (1050 aa) |
| | SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa) |
| | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1085 aa) |
| | MED21 | Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (160 aa) |
| | LOC101014817 | Uncharacterized protein. (259 aa) |
| | ENSPANP00000011993 | Nucleoplasmin domain-containing protein. (225 aa) |
| | ENSPANP00000012021 | Uncharacterized protein. (54 aa) |
| | KMT2D | Lysine methyltransferase 2D. (5563 aa) |
| | HCFC2 | Host cell factor C2. (792 aa) |
| | TRIM13 | Tripartite motif containing 13. (409 aa) |
| | DAXX | Death domain associated protein. (739 aa) |
| | HMGA1 | Uncharacterized protein. (201 aa) |
| | TAF11 | TATA-box binding protein associated factor 11. (211 aa) |
| | NUPR1 | Nuclear protein 1, transcriptional regulator. (100 aa) |
| | SRCAP | Uncharacterized protein. (3229 aa) |
| | FUS | FUS RNA binding protein. (533 aa) |
| | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa) |
| | BRD7 | Bromodomain containing 7. (652 aa) |
| | RRP1B | Ribosomal RNA processing 1B. (758 aa) |
| | SUPT3H | SPT3 homolog, SAGA and STAGA complex component. (336 aa) |
| | ARL2BP | ADP ribosylation factor like GTPase 2 binding protein. (163 aa) |
| | DYRK1A | Dual specificity tyrosine phosphorylation regulated kinase 1A. (763 aa) |
| | CBFB | Core-binding factor subunit beta. (187 aa) |
| | TRIP11 | Thyroid hormone receptor interactor 11. (1981 aa) |
| | SETD3 | Actin-histidine N-methyltransferase; Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin. (595 aa) |
| | DDX17 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. (733 aa) |
| | MTA1 | Metastasis associated 1. (723 aa) |
| | EP300 | E1A binding protein p300. (2427 aa) |
| | WBP2NL | WBP2 N-terminal like. (206 aa) |
| | TCF20 | Transcription factor 20. (1960 aa) |
| | IRF4 | Interferon regulatory factor 4. (437 aa) |
| | CREBBP | CREB binding protein. (2442 aa) |
| | TRIM27 | Tripartite motif containing 27. (513 aa) |
| | TRIM31 | Tripartite motif containing 31. (366 aa) |
| | MRTFB | Myocardin related transcription factor B. (1099 aa) |
| | TRIP4 | Thyroid hormone receptor interactor 4. (581 aa) |
| | PML | Promyelocytic leukemia. (882 aa) |
| | PRPF6 | Pre-mRNA processing factor 6. (941 aa) |
| | HELZ2 | Helicase with zinc finger 2. (2822 aa) |
| | SS18L1 | SS18L1 subunit of BAF chromatin remodeling complex. (396 aa) |
| | APEX1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa) |
| | ZXDC | ZXD family zinc finger C. (858 aa) |
| | NUCKS1 | Nuclear casein kinase and cyclin dependent kinase substrate 1. (243 aa) |
| | MCIDAS | Multiciliate differentiation and DNA synthesis associated cell cycle protein. (379 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | MED7 | Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (232 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (738 aa) |
| | CENPJ | Centromere protein J. (1340 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1158 aa) |
| | RERE | Arginine-glutamic acid dipeptide repeats. (1566 aa) |
| | ARID1B | AT-rich interaction domain 1B. (1539 aa) |
| | NOTCH1 | Notch receptor 1. (2541 aa) |
| | SSBP3 | Single stranded DNA binding protein 3. (388 aa) |
| | UTF1 | Undifferentiated embryonic cell transcription factor 1. (340 aa) |
| | RBPMS | RNA binding protein, mRNA processing factor. (219 aa) |
| | NCOA6 | Nuclear receptor coactivator 6. (2063 aa) |
| | ENSPANP00000016806 | Uncharacterized protein. (324 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa) |
| | ENSPANP00000017205 | Uncharacterized protein. (250 aa) |
| | FHL5 | Four and a half LIM domains 5. (284 aa) |
| | CITED4 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4. (184 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) |
| | DHX9 | DExH-box helicase 9. (1275 aa) |
| | TOX2 | TOX high mobility group box family member 2. (493 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (518 aa) |
| | LPIN3 | Lipin 3. (852 aa) |
| | TADA1 | Transcriptional adaptor 1. (335 aa) |
| | DRAP1 | DR1 associated protein 1. (205 aa) |
| | KAT2B | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa) |
| | TDRD3 | Tudor domain containing 3. (744 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (793 aa) |
| | ACTL6B | Actin like 6B; Belongs to the actin family. (426 aa) |
| | MED27 | Mediator complex subunit 27. (311 aa) |
| | RNF20 | E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa) |
| | TRIM14 | Tripartite motif containing 14. (442 aa) |
| | PSIP1 | PC4 and SFRS1 interacting protein 1. (530 aa) |
| | ENSPANP00000019257 | Uncharacterized protein. (272 aa) |
| | NIBAN2 | Niban apoptosis regulator 2. (746 aa) |
| | PHF2 | PHD finger protein 2. (1103 aa) |
| | GPS2 | G protein pathway suppressor 2. (327 aa) |
| | TRIM25 | Tripartite motif containing 25. (630 aa) |
| | PCBD1 | Pterin-4 alpha-carbinolamine dehydratase 1. (104 aa) |
| | MED13 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2174 aa) |
| | CCAR1 | Cell division cycle and apoptosis regulator 1. (1150 aa) |
| | TADA2A | Transcriptional adapter. (427 aa) |
| | SIRT1 | Sirtuin 1. (743 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1548 aa) |
| | ANKRD1 | Ankyrin repeat domain 1. (319 aa) |
| | JUP | Junction plakoglobin. (745 aa) |
| | PDLIM1 | PDZ and LIM domain 1. (330 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa) |
| | PSMC3IP | PSMC3 interacting protein. (217 aa) |
| | ATXN7L3 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (400 aa) |
| | MMS19 | MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa) |
| | PPRC1 | PPARG related coactivator 1. (1667 aa) |
| | TRIM8 | Tripartite motif containing 8. (551 aa) |
| | SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (531 aa) |
| | SFR1 | SWI5 dependent homologous recombination repair protein 1. (245 aa) |
| | ASXL1 | ASXL transcriptional regulator 1. (1545 aa) |
| | TCERG1 | Transcription elongation regulator 1. (1096 aa) |
| | PRMT2 | Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (446 aa) |
| | NCOA4 | Nuclear receptor coactivator 4. (651 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (479 aa) |
| | APBB1 | Amyloid beta precursor protein binding family B member 1. (738 aa) |
| | ENSPANP00000023376 | HMG box domain-containing protein. (177 aa) |
| | ENSPANP00000023587 | Uncharacterized protein. (151 aa) |
| | TRIM15 | Tripartite motif containing 15. (465 aa) |
| | WBP2 | WW domain binding protein 2. (256 aa) |
| | ENSPANP00000023862 | Uncharacterized protein. (453 aa) |
| | PKN1 | Protein kinase N1. (955 aa) |
| | SNW1 | SNW domain containing 1. (571 aa) |
| | ENSPANP00000024616 | HECT domain-containing protein. (55 aa) |
| | VGLL2 | Vestigial like family member 2. (317 aa) |
| | EDF1 | HTH cro/C1-type domain-containing protein. (161 aa) |
| | NRIP1 | Nuclear receptor interacting protein 1. (1155 aa) |
| | CDCA4 | Cell division cycle associated 4. (241 aa) |
| | ENSPANP00000000066 | ARL2_Bind_BART domain-containing protein. (148 aa) |
| | SRA1 | Steroid receptor RNA activator 1. (235 aa) |
| | CTBP1 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (440 aa) |
| | NPM1 | Nucleophosmin 1. (294 aa) |
| | WWTR1 | WW domain containing transcription regulator 1. (400 aa) |
| | POU2AF1 | POU class 2 homeobox associating factor 1. (153 aa) |
| | ARID1A | AT-rich interaction domain 1A. (2282 aa) |
| | ACTN4 | Actinin alpha 4. (931 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (990 aa) |
| | LPIN1 | Lipin 1. (1001 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (485 aa) |
| | ENSPANP00000027110 | Uncharacterized protein. (53 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1857 aa) |
| | MED24 | Mediator complex subunit 24. (1007 aa) |
| | ENSPANP00000027582 | Uncharacterized protein. (344 aa) |
| | ENSPANP00000028188 | Uncharacterized protein. (341 aa) |
| | ENSPANP00000028674 | Uncharacterized protein. (55 aa) |
| | MRTFA | Myocardin related transcription factor A. (970 aa) |
| | ENSPANP00000029043 | Uncharacterized protein. (86 aa) |
| | ENSPANP00000029172 | GAGE domain-containing protein. (68 aa) |
| | NCOA3 | Nuclear receptor coactivator. (1418 aa) |
| | ENSPANP00000029629 | ETS domain-containing protein. (384 aa) |
| | ENSPANP00000029665 | HECT domain-containing protein. (51 aa) |
| | ENSPANP00000029710 | Uncharacterized protein. (207 aa) |
| | TSG101 | Tumor susceptibility 101. (392 aa) |
| | ENSPANP00000030298 | HECT domain-containing protein. (728 aa) |
| | TRIM38 | Tripartite motif containing 38. (468 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | ENSPANP00000030957 | Uncharacterized protein. (313 aa) |
| | MAK | Male germ cell associated kinase. (648 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa) |
| | ENSPANP00000031871 | Uncharacterized protein. (249 aa) |
| | ENSPANP00000032162 | Uncharacterized protein. (292 aa) |
| | ENSPANP00000032304 | HTH cro/C1-type domain-containing protein. (140 aa) |
| | LMO2 | LIM domain only 2. (230 aa) |
| | ABL1 | Tyrosine-protein kinase. (1112 aa) |
| | LOC101008069 | Uncharacterized protein. (297 aa) |
| | MED23 | Mediator complex subunit 23. (1360 aa) |
| | ACTN2 | Actinin alpha 2. (894 aa) |
| | ACTN1 | Actinin alpha 1. (930 aa) |
