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| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (799 aa) |
| | BMP15 | Bone morphogenetic protein 15. (393 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (493 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | RGMB | Repulsive guidance molecule BMP co-receptor b. (539 aa) |
| | LOC101003314 | Uncharacterized protein. (889 aa) |
| | CCDC142 | Coiled-coil domain containing 142. (750 aa) |
| | HJV | Hemojuvelin BMP co-receptor. (426 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | LRRC32 | Leucine rich repeat containing 32. (662 aa) |
| | ZNF8 | Zinc finger protein 8. (575 aa) |
| | CHRD | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (955 aa) |
| | COL3A1 | Collagen type III alpha 1 chain. (1466 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | LOC101020633 | EGF-like domain-containing protein. (234 aa) |
| | LOC101011710 | Left-right determination factor. (366 aa) |
| | TGFBRAP1 | Transforming growth factor beta receptor associated protein 1. (943 aa) |
| | JADE2 | Jade family PHD finger 2. (834 aa) |
| | SPART | Spartin. (666 aa) |
| | HPGD | 15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa) |
| | INHA | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa) |
| | BMP10 | Bone morphogenetic protein 10. (424 aa) |
| | NCEH1 | Neutral cholesterol ester hydrolase 1. (440 aa) |
| | GDF3 | Growth differentiation factor 3. (335 aa) |
| | LTBP4 | Latent transforming growth factor beta binding protein 4. (1617 aa) |
| | EID2 | EP300 interacting inhibitor of differentiation 2. (236 aa) |
| | INHBC | Inhibin subunit beta C. (352 aa) |
| | ETV2 | ETS variant 2. (370 aa) |
| | NRROS | Negative regulator of reactive oxygen species. (692 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (670 aa) |
| | AMH | Anti-Mullerian hormone. (560 aa) |
| | BMP3 | Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa) |
| | CHRDL1 | Chordin like 1. (458 aa) |
| | SCX | Scleraxis bHLH transcription factor. (201 aa) |
| | TGFBR3 | Transforming growth factor beta receptor 3. (860 aa) |
| | SLC33A1 | Solute carrier family 33 member 1. (550 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa) |
| | TMPRSS6 | Transmembrane serine protease 6; Belongs to the peptidase S1 family. (809 aa) |
| | FURIN | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa) |
| | DUSP22 | Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa) |
| | STUB1 | STIP1 homology and U-box containing protein 1. (305 aa) |
| | BMP6 | Bone morphogenetic protein 6. (515 aa) |
| | GCNT2 | Glucosaminyl (N-acetyl) transferase 2 (I blood group). (402 aa) |
| | HIVEP1 | Human immunodeficiency virus type I enhancer binding protein 1. (2718 aa) |
| | HFE | Homeostatic iron regulator; Belongs to the MHC class I family. (348 aa) |
| | GLG1 | Golgi glycoprotein 1. (1057 aa) |
| | RNF111 | Ring finger protein 111. (985 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa) |
| | SMAD6 | Mothers against decapentaplegic homolog. (481 aa) |
| | JUND | JunD proto-oncogene, AP-1 transcription factor subunit. (309 aa) |
| | ENSPANP00000044589 | CFC domain-containing protein. (170 aa) |
| | ZCCHC18 | Zinc finger CCHC-type containing 18. (375 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (824 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | INHBE | Inhibin subunit beta E. (351 aa) |
| | BMPER | BMP binding endothelial regulator. (686 aa) |
| | MAGI2 | Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1456 aa) |
| | HNF1A | HNF1 homeobox A. (662 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | PXN | Paxillin. (1082 aa) |
| | USP9X | Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2507 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (230 aa) |
| | ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (500 aa) |
| | COMP | Cartilage oligomeric matrix protein. (841 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (472 aa) |
| | ENG | ZP domain-containing protein. (274 aa) |
| | PDCD4 | Programmed cell death 4. (470 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1067 aa) |
| | CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa) |
| | BMP5 | Bone morphogenetic protein 5. (471 aa) |
| | ENSPANP00000036120 | TPR_REGION domain-containing protein. (132 aa) |
| | APPL1 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (715 aa) |
| | AFP | Alpha fetoprotein. (622 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (414 aa) |
| | ABL1 | Tyrosine-protein kinase. (1112 aa) |
| | TGIF2 | TGFB induced factor homeobox 2. (237 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa) |
| | ZCCHC12 | Zinc finger CCHC-type containing 12. (402 aa) |
| | INHBB | Inhibin subunit beta B. (407 aa) |
| | NUP93 | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (880 aa) |
| | PPM1L | Protein phosphatase, Mg2+/Mn2+ dependent 1L. (360 aa) |
| | TWSG1 | Twisted gastrulation BMP signaling modulator 1. (237 aa) |
| | SMURF2 | SMAD specific E3 ubiquitin protein ligase 2. (682 aa) |
| | SMAD9 | Mothers against decapentaplegic homolog. (512 aa) |
| | HES5 | Hes family bHLH transcription factor 5. (166 aa) |
| | HEXA | Beta-hexosaminidase. (538 aa) |
| | SPTBN1 | Spectrin beta chain; Belongs to the spectrin family. (2366 aa) |
| | SRC | Tyrosine-protein kinase. (644 aa) |
| | FERMT2 | Fermitin family member 2. (681 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) |
| | WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa) |
| | MEGF8 | Multiple EGF like domains 8. (2825 aa) |
| | PTPRK | Protein tyrosine phosphatase receptor type K. (1471 aa) |
| | ATOH8 | Atonal bHLH transcription factor 8. (346 aa) |
| | LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa) |
| | AKAP4 | A-kinase anchoring protein 4. (854 aa) |
| | ACVR2B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (277 aa) |
| | ENSPANP00000024775 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (468 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | ONECUT2 | One cut domain family member. (504 aa) |
| | AMHR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (480 aa) |
| | ZNF831 | Zinc finger protein 831. (1670 aa) |
| | FKBP8 | Peptidylprolyl isomerase. (421 aa) |
| | ACVR1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa) |
| | GDF2 | Growth differentiation factor 2. (429 aa) |
| | RUNX2 | RUNX family transcription factor 2. (611 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa) |
| | BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | SOST | Sclerostin. (258 aa) |
| | SIRT1 | Sirtuin 1. (743 aa) |
| | NODAL | Nodal growth differentiation factor. (330 aa) |
| | MTMR4 | Myotubularin related protein 4. (1195 aa) |
| | TMEM100 | Transmembrane protein 100. (134 aa) |
| | GDF10 | Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa) |
| | DLX3 | Distal-less homeobox 3. (280 aa) |
| | BAMBI | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa) |
| | ITGA8 | Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | FAM83G | Family with sequence similarity 83 member G. (823 aa) |
| | FLCN | Folliculin. (680 aa) |
| | TGFBR3L | Transforming growth factor beta receptor 3 like. (310 aa) |
| | SMURF1 | E3 ubiquitin-protein ligase. (757 aa) |
| | MSX1 | Msh homeobox 1. (284 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | ENSPANP00000018389 | TGF_BETA_2 domain-containing protein. (391 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | HNF4A | Hepatocyte nuclear factor 4 alpha. (474 aa) |
| | COL1A2 | Collagen type I alpha 2 chain. (1366 aa) |
| | FUT8 | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (575 aa) |
| | BMP4 | Bone morphogenetic protein 4, isoform 3 (Predicted). (408 aa) |
| | ID1 | Inhibitor of DNA binding 1, HLH protein. (163 aa) |
| | GDF5 | Growth differentiation factor 5 (Predicted). (499 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | PML | Promyelocytic leukemia. (882 aa) |
| | RGMA | Repulsive guidance molecule BMP co-receptor a. (458 aa) |
| | BMP7 | Bone morphogenetic protein 7. (431 aa) |
| | AKAP3 | A-kinase anchoring protein 3. (857 aa) |
| | SMPD3 | Sphingomyelin phosphodiesterase 3. (655 aa) |
| | BTBD11 | BTB domain containing 11. (641 aa) |
| | TDGF1 | Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (187 aa) |
| | MSTN | Myostatin. (375 aa) |
| | FMOD | Fibromodulin. (444 aa) |
| | SKI | SKI proto-oncogene. (700 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (466 aa) |
| | SKIL | SKI like proto-oncogene. (684 aa) |
| | TBXT | T-box transcription factor T. (435 aa) |
| | GDF7 | Growth differentiation factor 7. (447 aa) |
| | EXT1 | Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). (746 aa) |
| | LTBP3 | Latent transforming growth factor beta binding protein 3. (1301 aa) |
| | LOC101011357 | Left-right determination factor. (366 aa) |
| | RBM14 | RNA binding motif protein 14. (669 aa) |
| | ITGB6 | Integrin beta; Belongs to the integrin beta chain family. (788 aa) |
| | BMP8B | TGF_BETA_2 domain-containing protein. (402 aa) |
| | SMAD5 | Mothers against decapentaplegic homolog. (465 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (498 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1158 aa) |
| | INHBA | Inhibin subunit beta A. (426 aa) |
| | ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | ACVR2A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa) |
| | LNPEP | Leucyl and cystinyl aminopeptidase. (1027 aa) |
| | TF | Transferrin; Belongs to the transferrin family. (701 aa) |
| | SLC39A5 | Solute carrier family 39 member 5. (540 aa) |
| | LTBP1 | Latent transforming growth factor beta binding protein 1. (1720 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (295 aa) |
| | DSG4 | Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1055 aa) |
| | FNTA | Farnesyltransferase, CAAX box, alpha. (379 aa) |
| | ZYX | Zyxin. (572 aa) |
| | ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa) |
| | CHST11 | Carbohydrate sulfotransferase. (352 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa) |
| | FST | Follistatin. (344 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (819 aa) |
| | DLX5 | Distal-less homeobox 5. (289 aa) |
| | GDF11 | Growth differentiation factor 11. (406 aa) |
| | GDF6 | Growth differentiation factor 6. (455 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | USP15 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa) |
| | NOTCH2 | Notch receptor 2. (2603 aa) |
| | LTBP2 | Latent transforming growth factor beta binding protein 2. (1821 aa) |
| | FOXH1 | Forkhead box H1. (366 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
