STRINGSTRING
HIVEP3 HIVEP3 BIN3 BIN3 RTL1 RTL1 HMG20B HMG20B MYOD1 MYOD1 NR4A1 NR4A1 BCL2 BCL2 PITX1 PITX1 BVES BVES COL19A1 COL19A1 MEF2D MEF2D MYL6 MYL6 CSRP3 CSRP3 POPDC2 POPDC2 CDK5 CDK5 IGSF8 IGSF8 MYH15 MYH15 KLHL40 KLHL40 MYF6 MYF6 R3HDM2 R3HDM2 MEGF10 MEGF10 EMD EMD DMD DMD TAZ TAZ SRPK3 SRPK3 LMOD3 LMOD3 ZBTB18 ZBTB18 CHRNA1 CHRNA1 CDON CDON DLL1 DLL1 WNT10B WNT10B BCL9L BCL9L RYR1 RYR1 DNER DNER CACNA1S CACNA1S HEYL HEYL HOXD9 HOXD9 ANKRD33 ANKRD33 SMYD1 SMYD1 ACTA1 ACTA1 ANKRD33B ANKRD33B CHRND CHRND STAC3 STAC3 HLX HLX KLF5 KLF5 BCL9 BCL9 CASQ1 CASQ1 RTL5 RTL5 MYF5 MYF5 ENSPANP00000010678 ENSPANP00000010678 BARX2 BARX2 METTL21C METTL21C PEG10 PEG10 POPDC3 POPDC3 TCF21 TCF21 EOMES EOMES MSC MSC FOXN2 FOXN2 ATF3 ATF3 SCX SCX MYL6B MYL6B GTF3C5 GTF3C5 LEMD2 LEMD2 MAPK14 MAPK14 NUPR1 NUPR1 MAFF MAFF EP300 EP300 SOX8 SOX8 RIPOR2 RIPOR2 CFL2 CFL2 SPG11 SPG11 COPS2 COPS2 WNT3A WNT3A PHOX2B PHOX2B VRK3 VRK3 SKI SKI R3HDM1 R3HDM1 NOTCH1 NOTCH1 FOS FOS VAX1 VAX1 CAV2 CAV2 CAV1 CAV1 MYOZ2 MYOZ2 SMO SMO GPCPD1 GPCPD1 MEOX2 MEOX2 SAP30 SAP30 SHH SHH MYOG MYOG CCNT2 CCNT2 RB1 RB1 KLHL41 KLHL41 KEL KEL PAX5 PAX5 PMP22 PMP22 PLEC PLEC NF1 NF1 MYOZ1 MYOZ1 HLF HLF EGR2 EGR2 ANKRD1 ANKRD1 CNTNAP1 CNTNAP1 NEURL1 NEURL1 FLNB FLNB EGR1 EGR1 PPP3CB PPP3CB MYOM1 MYOM1 ELN ELN VGLL2 VGLL2 BTG2 BTG2 NPHS1 NPHS1 KRAS KRAS MEF2C MEF2C MYLK2 MYLK2 NR2F2 NR2F2 HOXD10 HOXD10 ZNF689 ZNF689 PPP3CA PPP3CA P2RX5 P2RX5 RHOA RHOA SVIL SVIL SELENON SELENON P2RX2 P2RX2 SIX1 SIX1 ACTN1 ACTN1 MYH14 MYH14 SIX4 SIX4 ASB2 ASB2 ENSPANP00000025762 ENSPANP00000025762 DMRTA2 DMRTA2 ENSPANP00000029897 ENSPANP00000029897 ENSPANP00000030187 ENSPANP00000030187 HOMER1 HOMER1 ITGA7 ITGA7 MYLPF MYLPF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HIVEP3Human immunodeficiency virus type I enhancer binding protein 3. (2406 aa)
BIN3Bridging integrator 3. (253 aa)
RTL1Retrotransposon Gag like 1. (1359 aa)
HMG20BHigh mobility group 20B. (317 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (652 aa)
BCL2BCL2 apoptosis regulator. (238 aa)
PITX1Homeobox protein. (348 aa)
BVESBlood vessel epicardial substance. (360 aa)
COL19A1Collagen type XIX alpha 1 chain. (1142 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
MYL6Uncharacterized protein. (218 aa)
CSRP3Cysteine and glycine rich protein 3. (238 aa)
POPDC2Popeye domain containing 2. (364 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (302 aa)
IGSF8Immunoglobulin superfamily member 8. (613 aa)
MYH15Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1991 aa)
KLHL40Kelch like family member 40. (621 aa)
MYF6Myogenic factor 6. (242 aa)
R3HDM2R3H domain containing 2. (985 aa)
MEGF10Multiple EGF like domains 10. (1137 aa)
EMDLEM domain-containing protein. (255 aa)
DMDDystrophin. (3674 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (298 aa)
SRPK3SRSF protein kinase 3. (624 aa)
LMOD3Leiomodin 3. (556 aa)
ZBTB18Zinc finger and BTB domain containing 18. (531 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (502 aa)
CDONCell adhesion associated, oncogene regulated. (1264 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
BCL9LBCL9 like. (1500 aa)
RYR1Ryanodine receptor 1. (4842 aa)
DNERDelta/notch like EGF repeat containing. (737 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
HOXD9Homeobox D9. (352 aa)
ANKRD33Ankyrin repeat domain 33. (452 aa)
SMYD1SET and MYND domain containing 1. (490 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
ANKRD33BAnkyrin repeat domain 33B. (468 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (517 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
HLXH2.0 like homeobox. (494 aa)
KLF5Kruppel like factor 5. (457 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (372 aa)
RTL5Retrotransposon Gag like 5. (567 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (234 aa)
ENSPANP00000010678Uncharacterized protein. (152 aa)
BARX2BARX homeobox 2. (279 aa)
METTL21CMethyltransferase like 21C. (284 aa)
PEG10Paternally expressed 10. (774 aa)
POPDC3Popeye domain containing 3. (291 aa)
TCF21Transcription factor 21. (179 aa)
EOMESEomesodermin. (705 aa)
MSCMusculin. (206 aa)
FOXN2Forkhead box N2. (431 aa)
ATF3Activating transcription factor 3. (181 aa)
SCXScleraxis bHLH transcription factor. (201 aa)
MYL6BMyosin light chain 6B. (210 aa)
GTF3C5General transcription factor IIIC subunit 5. (528 aa)
LEMD2LEM domain containing 2. (499 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (100 aa)
MAFFMAF bZIP transcription factor F. (164 aa)
EP300E1A binding protein p300. (2427 aa)
SOX8SRY-box transcription factor 8. (446 aa)
RIPOR2RHO family interacting cell polarization regulator 2. (1046 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2442 aa)
COPS2COP9 signalosome subunit 2. (450 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
VRK3VRK serine/threonine kinase 3. (471 aa)
SKISKI proto-oncogene. (700 aa)
R3HDM1R3H domain containing 1. (1100 aa)
NOTCH1Notch receptor 1. (2541 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
VAX1Ventral anterior homeobox 1. (333 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
MYOZ2Myozenin 2. (264 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
GPCPD1Glycerophosphocholine phosphodiesterase 1. (672 aa)
MEOX2Mesenchyme homeobox 2. (291 aa)
SAP30Sin3A associated protein 30. (220 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (456 aa)
MYOGMyogenin. (249 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
RB1RB transcriptional corepressor 1. (889 aa)
KLHL41Kelch like family member 41. (606 aa)
KELKell metallo-endopeptidase (Kell blood group). (732 aa)
PAX5Paired box 5. (364 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
PLECUncharacterized protein. (4680 aa)
NF1Neurofibromin 1. (2839 aa)
MYOZ1Myozenin 1. (299 aa)
HLFHLF transcription factor, PAR bZIP family member. (295 aa)
EGR2Early growth response 2. (415 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
CNTNAP1Contactin associated protein 1. (1380 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
FLNBFilamin B. (2633 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
MYOM1Myomesin 1. (1663 aa)
ELNElastin. (633 aa)
VGLL2Vestigial like family member 2. (317 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1227 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (414 aa)
HOXD10Homeobox D10. (340 aa)
ZNF689Zinc finger protein 689. (421 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (366 aa)
RHOARas homolog family member A. (193 aa)
SVILSupervillin. (2310 aa)
SELENONSelenoprotein N. (557 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (496 aa)
SIX1SIX homeobox 1. (284 aa)
ACTN1Actinin alpha 1. (930 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa)
SIX4SIX homeobox 4. (780 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (637 aa)
ENSPANP00000025762Uncharacterized protein. (157 aa)
DMRTA2DMRT like family A2. (513 aa)
ENSPANP00000029897Uncharacterized protein. (115 aa)
ENSPANP00000030187HP domain-containing protein. (75 aa)
HOMER1Homer scaffold protein 1. (366 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (198 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
Server load: low (16%) [HD]