STRINGSTRING
APOA2 APOA2 BAD BAD SLC30A8 SLC30A8 PTK2B PTK2B PCSK1 PCSK1 LIN28A LIN28A GCLM GCLM NEUROD1 NEUROD1 EIF2B5 EIF2B5 ACVR1C ACVR1C FGF21 FGF21 LOC101004221 LOC101004221 TGFB1 TGFB1 CASR CASR PRKAA2 PRKAA2 PTPRN PTPRN PIK3CA PIK3CA ADCY8 ADCY8 GPER1 GPER1 TGFBR2 TGFBR2 GATA4 GATA4 SLC12A7 SLC12A7 SMAD4 SMAD4 TRA2B TRA2B RBM4B RBM4B COL4A3 COL4A3 GYS2 GYS2 EIF2B4 EIF2B4 PDK3 PDK3 PRLH PRLH NR0B2 NR0B2 GAS6 GAS6 SIN3A SIN3A CPB2 CPB2 LOC101003421 LOC101003421 GJB6 GJB6 ENSPANP00000010179 ENSPANP00000010179 MEN1 MEN1 CCDC186 CCDC186 PTPRN2 PTPRN2 GIPR GIPR RESP18 RESP18 SESN2 SESN2 AQP4 AQP4 AGER AGER PPARD PPARD TREM2 TREM2 COL6A2 COL6A2 SRF SRF PFKL PFKL SLC29A1 SLC29A1 GCLC GCLC TXN2 TXN2 SOX4 SOX4 GPLD1 GPLD1 KCNB1 KCNB1 ILDR2 ILDR2 LPL LPL EIF2B2 EIF2B2 SLC12A6 SLC12A6 NPTX1 NPTX1 ERN1 ERN1 NKX2-2 NKX2-2 HNF4A HNF4A ANGPT2 ANGPT2 GLUL GLUL CCN2 CCN2 SERPINF1 SERPINF1 SREBF1 SREBF1 SARM1 SARM1 GIP GIP GJD3 GJD3 PAX2 PAX2 TWNK TWNK IRS2 IRS2 EGR1 EGR1 CDKN1B CDKN1B GPAM GPAM TJP1 TJP1 PKLR PKLR RAB11FIP5 RAB11FIP5 ACVR2B ACVR2B TH TH SIDT2 SIDT2 SELENOT SELENOT RACK1 RACK1 HIF1A HIF1A ADIPOQ ADIPOQ RPS6KB1 RPS6KB1 XBP1 XBP1 TCF7L2 TCF7L2 GHRHR GHRHR PCK2 PCK2 THBS1 THBS1 RAB11FIP2 RAB11FIP2 MLXIPL MLXIPL GRIK5 GRIK5 SLC37A4 SLC37A4 IGF1R IGF1R SMAD2 SMAD2 RASAL2 RASAL2 SLC39A14 SLC39A14 ZNF236 ZNF236 CYBA CYBA FN1 FN1 HNF1A HNF1A PCK1 PCK1 FKBP1B FKBP1B GCK GCK PPP3CA PPP3CA SLC8A1 SLC8A1 CLTRN CLTRN SELENOS SELENOS PRKAA1 PRKAA1 ZBTB20 ZBTB20
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APOA2Apolipoprotein A2. (132 aa)
BADBCL2 associated agonist of cell death. (168 aa)
SLC30A8Solute carrier family 30 member 8. (369 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (749 aa)
LIN28ALin-28 homolog A. (209 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (274 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (721 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
FGF21Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family. (174 aa)
LOC101004221Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CASRCalcium sensing receptor. (1081 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
PTPRNUncharacterized protein. (979 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
GATA4GATA binding protein 4. (442 aa)
SLC12A7Solute carrier family 12 member 7. (1085 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TRA2BTransformer 2 beta homolog. (288 aa)
RBM4BRNA binding motif protein 4B. (359 aa)
COL4A3Collagen type IV alpha 3 chain. (1670 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (544 aa)
PDK3Protein-serine/threonine kinase. (415 aa)
PRLHProlactin releasing hormone. (87 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
GAS6Growth arrest specific 6. (679 aa)
SIN3ASIN3 transcription regulator family member A. (1197 aa)
CPB2Carboxypeptidase B2. (423 aa)
LOC101003421BZIP domain-containing protein. (371 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
ENSPANP00000010179Thioredoxin domain-containing protein. (163 aa)
MEN1Uncharacterized protein. (610 aa)
CCDC186Coiled-coil domain containing 186. (898 aa)
PTPRN2Protein tyrosine phosphatase receptor type N2. (1015 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
RESP18Regulated endocrine specific protein 18. (228 aa)
SESN2Sestrin 2. (480 aa)
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
AGERAdvanced glycosylation end-product specific receptor. (418 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
COL6A2Collagen type VI alpha 2 chain. (990 aa)
SRFSerum response factor. (508 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
SLC29A1Solute carrier family 29 member 1 (Augustine blood group). (538 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
TXN2Thioredoxin 2. (166 aa)
SOX4Transcription factor SOX. (448 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (841 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
ILDR2Immunoglobulin like domain containing receptor 2. (639 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
SLC12A6Solute carrier family 12 member 6. (1150 aa)
NPTX1Neuronal pentraxin 1. (432 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (977 aa)
NKX2-2NK2 homeobox 2. (273 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
ANGPT2Angiopoietin 2. (496 aa)
GLULGlutamate-ammonia ligase; Belongs to the glutamine synthetase family. (369 aa)
CCN2Connective tissue growth factor (Predicted). (349 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
SARM1Sterile alpha and TIR motif containing 1. (724 aa)
GIPGastric inhibitory polypeptide. (137 aa)
GJD3Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (295 aa)
PAX2Paired box 2. (436 aa)
TWNKTwinkle mtDNA helicase. (684 aa)
IRS2Insulin receptor substrate 2. (1316 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1758 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
RAB11FIP5Uncharacterized protein. (1318 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
THTyrosine hydroxylase. (549 aa)
SIDT2SID1 transmembrane family member 2. (860 aa)
SELENOTSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (189 aa)
RACK1Receptor for activated C kinase 1. (393 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (832 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (275 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
XBP1BZIP domain-containing protein. (380 aa)
TCF7L2Transcription factor 7 like 2. (529 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (468 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (645 aa)
THBS1Thrombospondin 1. (1175 aa)
RAB11FIP2RAB11 family interacting protein 2. (531 aa)
MLXIPLMLX interacting protein like. (880 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (972 aa)
SLC37A4Solute carrier family 37 member 4. (451 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
SMAD2Mothers against decapentaplegic homolog. (472 aa)
RASAL2RAS protein activator like 2. (1280 aa)
SLC39A14Solute carrier family 39 member 14. (490 aa)
ZNF236Zinc finger protein 236. (1826 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (195 aa)
FN1Fibronectin 1. (2477 aa)
HNF1AHNF1 homeobox A. (662 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
FKBP1BPeptidylprolyl isomerase. (95 aa)
GCKPhosphotransferase. (480 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
CLTRNCollectrin domain-containing protein. (222 aa)
SELENOSSelenoprotein S. (211 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
ZBTB20Zinc finger and BTB domain containing 20. (751 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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