STRINGSTRING
HOXC4 HOXC4 ENSPANP00000043407 ENSPANP00000043407 FAM76A FAM76A HEY2 HEY2 TDRD1 TDRD1 DKK1 DKK1 BMPR1A BMPR1A CDX2 CDX2 PCSK6 PCSK6 HOXC6 HOXC6 ALDH1A2 ALDH1A2 RARG RARG HES6 HES6 PAX6 PAX6 BMP2 BMP2 WLS WLS OTX2 OTX2 CTNNBIP1 CTNNBIP1 GLI3 GLI3 WT1 WT1 TASOR TASOR SMAD2 SMAD2 COBL COBL LFNG LFNG HOXD8 HOXD8 LEF1 LEF1 TP53 TP53 ABI1 ABI1 LOC101026281 LOC101026281 ENSPANP00000031315 ENSPANP00000031315 HES5 HES5 LRP5 LRP5 EN1 EN1 BASP1 BASP1 TULP3 TULP3 LDB1 LDB1 TCF15 TCF15 HOXB2 HOXB2 BTG2 BTG2 PCDH8 PCDH8 ACVR2B ACVR2B ENSPANP00000024775 ENSPANP00000024775 ENSPANP00000024557 ENSPANP00000024557 HOXC8 HOXC8 BHLHE41 BHLHE41 TSHZ1 TSHZ1 FOXA2 FOXA2 ARC ARC MED12 MED12 HIPK1 HIPK1 TBX1 TBX1 BPTF BPTF HOXA10 HOXA10 HOXA7 HOXA7 PBX3 PBX3 CDX4 CDX4 NOG NOG NEUROD1 NEUROD1 DLL3 DLL3 SFRP1 SFRP1 HOXC11 HOXC11 SFRP2 SFRP2 HOXC9 HOXC9 HES1 HES1 HOXC5 HOXC5 ATP6AP2 ATP6AP2 TAF10 TAF10 MYF6 MYF6 TDRD10 TDRD10 RIPPLY2 RIPPLY2 SOX17 SOX17 OTX1 OTX1 HEY1 HEY1 GDF11 GDF11 TBX3 TBX3 NRARP NRARP C2orf66 C2orf66 FOXC2 FOXC2 OSR1 OSR1 FOXH1 FOXH1 PBX1 PBX1 KDM2B KDM2B CTNNB1 CTNNB1 CDON CDON FAM76B FAM76B FOXF1 FOXF1 RNF2 RNF2 DLL1 DLL1 WNT5A WNT5A BMPR2 BMPR2 SEMA3C SEMA3C HEYL HEYL MSGN1 MSGN1 HOXD9 HOXD9 GATA4 GATA4 SMAD4 SMAD4 LOC101020633 LOC101020633 GRSF1 GRSF1 WNT8A WNT8A HOXD3 HOXD3 HOXA5 HOXA5 HOXA6 HOXA6 PGAP1 PGAP1 ALX4 ALX4 LRP6 LRP6 MTHFSD MTHFSD FRS2 FRS2 HOXC13 HOXC13 GBX2 GBX2 NEUROG1 NEUROG1 NKX3-1 NKX3-1 FZD5 FZD5 GDF3 GDF3 HOXC10 HOXC10 PLXNA2 PLXNA2 MIB1 MIB1 TMED2 TMED2 ZBTB16 ZBTB16 MYF5 MYF5 HOXA2 HOXA2 ATM ATM FEZF2 FEZF2 TIFAB TIFAB HOXA11 HOXA11 HELT HELT FEZF1 FEZF1 FOXB1 FOXB1 CDX1 CDX1 HES3 HES3 TBX18 TBX18 XRCC2 XRCC2 EPB41L5 EPB41L5 PALB2 PALB2 TBX6 TBX6 SRF SRF TDRD6 TDRD6 ETS2 ETS2 EP300 EP300 FOXC1 FOXC1 SMAD3 SMAD3 MESP1 MESP1 MESP2 MESP2 AURKA AURKA HOXA3 HOXA3 RIPPLY1 RIPPLY1 WNT3A WNT3A TDGF1 TDGF1 HOXD13 HOXD13 SKI SKI TDRD15 TDRD15 TBXT TBXT PRKDC PRKDC HIPK2 HIPK2 NOTCH1 NOTCH1 CRKL CRKL SSBP3 SSBP3 POGLUT1 POGLUT1 ACVR2A ACVR2A EMX2 EMX2 AXIN2 AXIN2 SMO SMO POFUT1 POFUT1 BMP4 BMP4 PAX1 PAX1 MEOX2 MEOX2 SHH SHH SIX2 SIX2 HES2 HES2 HOXA4 HOXA4 DDIT3 DDIT3 WNT1 WNT1 MSX1 MSX1 HOXD4 HOXD4 CRB2 CRB2 MLLT3 MLLT3 CER1 CER1 PCSK5 PCSK5 BARX1 BARX1 HES4 HES4 HES7 HES7 PLD6 PLD6 NLE1 NLE1 HOXB1 HOXB1 HOXB4 HOXB4 HOXB5 HOXB5 HOXB6 HOXB6 HOXB7 HOXB7 HOXB8 HOXB8 HOXB9 HOXB9 NODAL NODAL PCGF2 PCGF2 TCAP TCAP HHEX HHEX CYP26C1 CYP26C1 KAT2A KAT2A MEOX1 MEOX1 WNT3 WNT3 FGF8 FGF8 HOXD10 HOXD10 PSEN1 PSEN1 NR2F2 NR2F2 TDRKH TDRKH DCANP1 DCANP1 ENSPANP00000044589 ENSPANP00000044589 TDRD5 TDRD5 ZIC3 ZIC3 HOXB3 HOXB3 ENSPANP00000046764 ENSPANP00000046764 TGFBR1 TGFBR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOXC4Homeobox C4. (264 aa)
ENSPANP00000043407Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (190 aa)
FAM76AFamily with sequence similarity 76 member A. (341 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (326 aa)
TDRD1Tudor domain containing 1. (1190 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
CDX2Caudal type homeobox 2. (313 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (944 aa)
HOXC6Homeobox C6. (235 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (540 aa)
RARGRetinoic acid receptor gamma. (463 aa)
HES6Hes family bHLH transcription factor 6. (180 aa)
PAX6Paired box 6. (462 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
WLSWnt ligand secretion mediator. (543 aa)
OTX2Orthodenticle homeobox 2. (289 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
GLI3GLI family zinc finger 3. (1580 aa)
WT1WT1 transcription factor. (510 aa)
TASORTranscription activation suppressor. (1612 aa)
SMAD2Mothers against decapentaplegic homolog. (472 aa)
COBLCordon-bleu WH2 repeat protein. (1309 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (379 aa)
HOXD8Homeobox D8. (288 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
ABI1Abl interactor 1. (508 aa)
LOC101026281RING-type domain-containing protein. (319 aa)
ENSPANP00000031315Homeobox domain-containing protein. (140 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1612 aa)
EN1Homeobox protein engrailed-like. (396 aa)
BASP1Uncharacterized protein. (110 aa)
TULP3TUB like protein 3; Belongs to the TUB family. (490 aa)
LDB1LIM domain binding 1. (411 aa)
TCF15Transcription factor 15. (198 aa)
HOXB2Homeobox B2. (337 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
PCDH8Protocadherin 8. (1048 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
ENSPANP00000024775Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (468 aa)
ENSPANP00000024557GOLD domain-containing protein. (188 aa)
HOXC8Homeobox C8. (242 aa)
BHLHE41Basic helix-loop-helix family member e41. (481 aa)
TSHZ1Teashirt zinc finger homeobox 1. (1077 aa)
FOXA2Forkhead box A2. (463 aa)
ARCActivity regulated cytoskeleton associated protein. (396 aa)
MED12Mediator complex subunit 12. (2178 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
TBX1T-box transcription factor 1. (491 aa)
BPTFBromodomain PHD finger transcription factor. (2978 aa)
HOXA10Homeobox domain-containing protein. (395 aa)
HOXA7Homeobox domain-containing protein. (223 aa)
PBX3Homeobox domain-containing protein. (395 aa)
CDX4Caudal type homeobox 4. (259 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
DLL3Delta like canonical Notch ligand 3. (618 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
HOXC11Homeobox C11. (378 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
HOXC5Homeobox C5. (222 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (350 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
MYF6Myogenic factor 6. (242 aa)
TDRD10Tudor domain containing 10. (366 aa)
RIPPLY2Ripply transcriptional repressor 2. (128 aa)
SOX17SRY-box transcription factor 17. (412 aa)
OTX1Orthodenticle homeobox 1. (354 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
GDF11Growth differentiation factor 11. (406 aa)
TBX3T-box transcription factor 3. (743 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
C2orf66Chromosome 2 open reading frame 66. (117 aa)
FOXC2Forkhead box C2. (494 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
FOXH1Forkhead box H1. (366 aa)
PBX1PBX homeobox 1. (430 aa)
KDM2BLysine demethylase 2B. (1338 aa)
CTNNB1Catenin beta 1. (781 aa)
CDONCell adhesion associated, oncogene regulated. (1264 aa)
FAM76BFamily with sequence similarity 76 member B. (339 aa)
FOXF1Forkhead box F1. (432 aa)
RNF2Ring finger protein 2. (336 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
MSGN1Mesogenin 1. (193 aa)
HOXD9Homeobox D9. (352 aa)
GATA4GATA binding protein 4. (442 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
LOC101020633EGF-like domain-containing protein. (234 aa)
GRSF1G-rich RNA sequence binding factor 1. (581 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
HOXD3Homeobox D3. (432 aa)
HOXA5Homeobox A5 (Predicted). (270 aa)
HOXA6Homeobox A6. (233 aa)
PGAP1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (898 aa)
ALX4ALX homeobox 4. (409 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
MTHFSDMethenyltetrahydrofolate synthetase domain containing. (383 aa)
FRS2Fibroblast growth factor receptor substrate 2. (522 aa)
HOXC13Homeobox C13. (318 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
NEUROG1Neurogenin 1. (237 aa)
NKX3-1NK3 homeobox 1. (232 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
GDF3Growth differentiation factor 3. (335 aa)
HOXC10Homeobox C10. (341 aa)
PLXNA2Plexin A2. (1909 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (234 aa)
HOXA2Homeobox protein Hox-A2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. Proboscipedia subfamily. (377 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
FEZF2FEZ family zinc finger 2. (457 aa)
TIFABTIFA inhibitor. (162 aa)
HOXA11Homeobox A11 (Predicted). (311 aa)
HELTHelt bHLH transcription factor. (327 aa)
FEZF1FEZ family zinc finger 1. (475 aa)
FOXB1Forkhead box B1. (325 aa)
CDX1Caudal type homeobox 1. (265 aa)
HES3Hes family bHLH transcription factor 3. (185 aa)
TBX18T-box transcription factor 18. (607 aa)
XRCC2X-ray repair cross complementing 2. (280 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (688 aa)
PALB2Partner and localizer of BRCA2. (1184 aa)
TBX6T-box transcription factor 6. (436 aa)
SRFSerum response factor. (508 aa)
TDRD6Tudor domain containing 6. (2097 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
EP300E1A binding protein p300. (2427 aa)
FOXC1Fork-head domain-containing protein. (210 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (272 aa)
MESP2Mesoderm posterior bHLH transcription factor 2. (373 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (403 aa)
HOXA3Homeobox domain-containing protein. (443 aa)
RIPPLY1Ripply transcriptional repressor 1. (151 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (187 aa)
HOXD13Homeobox D13. (343 aa)
SKISKI proto-oncogene. (700 aa)
TDRD15Tudor domain containing 15. (1935 aa)
TBXTT-box transcription factor T. (435 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4094 aa)
HIPK2Homeodomain interacting protein kinase 2. (1158 aa)
NOTCH1Notch receptor 1. (2541 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
SSBP3Single stranded DNA binding protein 3. (388 aa)
POGLUT1Protein O-glucosyltransferase 1. (392 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
EMX2Empty spiracles homeobox 2. (252 aa)
AXIN2Axin 2. (844 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
POFUT1Protein O-fucosyltransferase 1. (388 aa)
BMP4Bone morphogenetic protein 4, isoform 3 (Predicted). (408 aa)
PAX1Paired box 1. (535 aa)
MEOX2Mesenchyme homeobox 2. (291 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (456 aa)
SIX2SIX homeobox 2. (290 aa)
HES2Hes family bHLH transcription factor 2. (173 aa)
HOXA4Homeobox A4 (Predicted). (320 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (192 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
MSX1Msh homeobox 1. (284 aa)
HOXD4Homeobox D4. (255 aa)
CRB2Crumbs cell polarity complex component 2. (1290 aa)
MLLT3MLLT3 super elongation complex subunit. (570 aa)
CER1Cerberus 1, DAN family BMP antagonist. (269 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1843 aa)
BARX1BARX homeobox 1. (254 aa)
HES4Hes family bHLH transcription factor 4. (221 aa)
HES7Hes family bHLH transcription factor 7. (230 aa)
PLD6Phospholipase D family member 6. (252 aa)
NLE1Notchless homolog 1. (485 aa)
HOXB1Homeobox B1. (304 aa)
HOXB4Homeobox B4. (251 aa)
HOXB5Homeobox B5. (269 aa)
HOXB6Homeobox B6. (224 aa)
HOXB7Homeobox B7. (217 aa)
HOXB8Homeobox B8. (254 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
NODALNodal growth differentiation factor. (330 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
TCAPTitin-cap. (167 aa)
HHEXHematopoietically expressed homeobox. (270 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
MEOX1Mesenchyme homeobox 1. (254 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
HOXD10Homeobox D10. (340 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (452 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (414 aa)
TDRKHTudor and KH domain containing. (596 aa)
DCANP1Dendritic cell associated nuclear protein. (197 aa)
ENSPANP00000044589CFC domain-containing protein. (170 aa)
TDRD5Tudor domain containing 5. (1007 aa)
ZIC3Zic family member 3. (466 aa)
HOXB3Homeobox B3. (433 aa)
ENSPANP00000046764Uncharacterized protein. (285 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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