STRINGSTRING
TBX5 TBX5 FOXA2 FOXA2 FUZ FUZ NOG NOG SFRP1 SFRP1 SFRP2 SFRP2 TGFB2 TGFB2 SMAD7 SMAD7 EPHA4 EPHA4 PPP2CA PPP2CA SPRY2 SPRY2 EFNA1 EFNA1 VASN VASN SPRY1 SPRY1 SDHAF2 SDHAF2 DACT3 DACT3 USF3 USF3 IL17RD IL17RD SPRED1 SPRED1 ZNF750 ZNF750 FOXA1 FOXA1 OVOL2 OVOL2 MAD2L2 MAD2L2 GATA3 GATA3 PTEN PTEN NKX2-1 NKX2-1 DAB2IP DAB2IP HPN HPN LDLRAD4 LDLRAD4 PAWR PAWR MARK1 MARK1 BMP5 BMP5 SPRED2 SPRED2 SPRED3 SPRED3 TRIM62 TRIM62
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBX5T-box transcription factor 5. (518 aa)
FOXA2Forkhead box A2. (463 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SMAD7Mothers against decapentaplegic homolog. (493 aa)
EPHA4EPH receptor A4. (986 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
SPRY2Sprouty RTK signaling antagonist 2. (338 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
VASNVasorin. (673 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
SDHAF2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (166 aa)
DACT3Dishevelled binding antagonist of beta catenin 3. (631 aa)
USF3Upstream transcription factor family member 3. (2245 aa)
IL17RDInterleukin 17 receptor D. (739 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
ZNF750Zinc finger protein 750. (723 aa)
FOXA1Forkhead box A1. (470 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (224 aa)
GATA3GATA binding protein 3. (444 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
NKX2-1NK2 homeobox 1. (401 aa)
DAB2IPDAB2 interacting protein. (1183 aa)
HPNHepsin; Belongs to the peptidase S1 family. (421 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (306 aa)
PAWRPro-apoptotic WT1 regulator. (342 aa)
MARK1Non-specific serine/threonine protein kinase. (791 aa)
BMP5Bone morphogenetic protein 5. (471 aa)
SPRED2Sprouty related EVH1 domain containing 2. (432 aa)
SPRED3Sprouty related EVH1 domain containing 3. (456 aa)
TRIM62Tripartite motif containing 62. (463 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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