STRINGSTRING
BIK BIK BAD BAD SPIRE1 SPIRE1 MGARP MGARP DDHD2 DDHD2 RALBP1 RALBP1 SSBP1 SSBP1 BBC3 BBC3 VPS13D VPS13D PRKN PRKN TNFSF10 TNFSF10 PGAM5 PGAM5 GPER1 GPER1 FAM162A FAM162A ATP5IF1 ATP5IF1 HTRA2 HTRA2 GSK3A GSK3A ENSPANP00000008508 ENSPANP00000008508 CAMKK2 CAMKK2 HRK HRK VDAC1 VDAC1 HIP1R HIP1R SLC25A4 SLC25A4 SLC25A6 SLC25A6 PYCARD PYCARD VPS35 VPS35 TREM2 TREM2 PLA2G6 PLA2G6 SIVA1 SIVA1 MIEF1 MIEF1 AURKA AURKA KDR KDR LOC101016948 LOC101016948 RALA RALA ADCK1 ADCK1 BNIP3 BNIP3 BMF BMF DDHD1 DDHD1 BID BID MMP9 MMP9 CIDEB CIDEB GZMB GZMB BCL2L11 BCL2L11 DNM1L DNM1L PINK1 PINK1 PPARGC1A PPARGC1A STOML2 STOML2 PLD6 PLD6 MIEF2 MIEF2 PPIF PPIF MCU MCU MARCHF5 MARCHF5 ZDHHC6 ZDHHC6 MFF MFF DCN DCN ENSPANP00000021879 ENSPANP00000021879 AMBRA1 AMBRA1 ENSPANP00000022457 ENSPANP00000022457 HTT HTT CYP2C8-2 CYP2C8-2 GSK3B GSK3B HIF1A HIF1A BOK BOK MUL1 MUL1 PARK7 PARK7 ENSPANP00000031250 ENSPANP00000031250 ENSPANP00000031797 ENSPANP00000031797 CHCHD10 CHCHD10 TP53 TP53 MAPK8 MAPK8 ENSPANP00000033770 ENSPANP00000033770 ENSPANP00000035288 ENSPANP00000035288 ZNF205 ZNF205 BAX BAX MAPK10 MAPK10 FBXO7 FBXO7 BAK1 BAK1 MLLT11 MLLT11 MOAP1 MOAP1 ENSPANP00000047688 ENSPANP00000047688
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BIKBCL2 interacting killer. (160 aa)
BADBCL2 associated agonist of cell death. (168 aa)
SPIRE1Spire type actin nucleation factor 1. (756 aa)
MGARPMitochondria localized glutamic acid rich protein. (240 aa)
DDHD2DDHD domain containing 2. (711 aa)
RALBP1RalA binding protein 1. (655 aa)
SSBP1Single stranded DNA binding protein 1. (148 aa)
BBC3BCL2 binding component 3. (261 aa)
VPS13DVacuolar protein sorting 13 homolog D. (4373 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (289 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
FAM162AFamily with sequence similarity 162 member A. (155 aa)
ATP5IF1Uncharacterized protein. (106 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
ENSPANP00000008508Uncharacterized protein. (270 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (588 aa)
HRKActivator of apoptosis harakiri; Promotes apoptosis. (91 aa)
VDAC1Voltage dependent anion channel 1. (289 aa)
HIP1RHuntingtin interacting protein 1 related. (1068 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (290 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (232 aa)
PYCARDPYD and CARD domain containing. (195 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
SIVA1Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa)
MIEF1Mitochondrial elongation factor 1. (472 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (403 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1315 aa)
LOC101016948ATPase inhibitor, mitochondrial. (106 aa)
RALARAS like proto-oncogene A. (206 aa)
ADCK1AarF domain containing kinase 1. (523 aa)
BNIP3BCL2 interacting protein 3. (259 aa)
BMFBcl2 modifying factor. (206 aa)
DDHD1DDHD domain containing 1. (899 aa)
BIDBH3 interacting domain death agonist. (244 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
CIDEBCell death inducing DFFA like effector b. (220 aa)
GZMBGranzyme B; Belongs to the peptidase S1 family. (281 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa)
PINK1PTEN induced kinase 1. (581 aa)
PPARGC1APPARG coactivator 1 alpha. (793 aa)
STOML2Stomatin like 2. (361 aa)
PLD6Phospholipase D family member 6. (252 aa)
MIEF2Mitochondrial elongation factor 2. (465 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa)
MCUMitochondrial calcium uniporter. (351 aa)
MARCHF5Membrane associated ring-CH-type finger 5. (278 aa)
ZDHHC6Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (416 aa)
MFFMitochondrial fission factor. (342 aa)
DCNDecorin; May affect the rate of fibrils formation. (359 aa)
ENSPANP00000021879Uncharacterized protein. (453 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1308 aa)
ENSPANP00000022457Uncharacterized protein. (208 aa)
HTTHuntingtin. (3118 aa)
CYP2C8-2Uncharacterized protein. (283 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (832 aa)
BOKBCL2 family apoptosis regulator BOK. (212 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
ENSPANP00000031250Miff domain-containing protein. (81 aa)
ENSPANP00000031797Uncharacterized protein. (72 aa)
CHCHD10Coiled-coil-helix-coiled-coil-helix domain containing 10. (173 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSPANP00000033770Rho-GAP domain-containing protein. (544 aa)
ENSPANP00000035288Rho-GAP domain-containing protein. (606 aa)
ZNF205Zinc finger protein 205. (555 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
MAPK10Mitogen-activated protein kinase. (467 aa)
FBXO7F-box protein 7, isoform 1 (Predicted). (522 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
MLLT11MLLT11 transcription factor 7 cofactor. (90 aa)
MOAP1Modulator of apoptosis 1. (351 aa)
ENSPANP00000047688Uncharacterized protein. (212 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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