STRINGSTRING
ZFP36L1 ZFP36L1 FOSL1 FOSL1 P2RY11 P2RY11 P2RY1 P2RY1 P2RY12 P2RY12 RAPGEF3 RAPGEF3 ENSPANP00000000847 ENSPANP00000000847 BIRC2 BIRC2 SSH1 SSH1 PTK2B PTK2B ENSPANP00000001602 ENSPANP00000001602 PPARGC1B PPARGC1B PDE3A PDE3A CREB1 CREB1 CHEK1 CHEK1 PFKFB1 PFKFB1 GATA6 GATA6 CASQ2 CASQ2 HCN3 HCN3 PANX1 PANX1 NDUFS4 NDUFS4 HCN1 HCN1 FOSB FOSB IGFBP5 IGFBP5 PKD2 PKD2 SLC26A6 SLC26A6 CRHBP CRHBP SLC26A3 SLC26A3 RAP1B RAP1B WNT10B WNT10B XRN1 XRN1 RYR1 RYR1 CACNA1S CACNA1S ADSS2 ADSS2 BCKDHB BCKDHB STC1 STC1 CFTR CFTR CPS1 CPS1 GATA1 GATA1 CARM1 CARM1 P2RY2 P2RY2 HMGCS2 HMGCS2 GPD1 GPD1 P2RY4 P2RY4 PENK PENK MMP19 MMP19 TRPC3 TRPC3 PTGS2 PTGS2 DGKQ DGKQ ITPR2 ITPR2 P2RX7 P2RX7 P2RY6 P2RY6 KCNQ1 KCNQ1 SLC5A5 SLC5A5 LOC101014578 LOC101014578 CNGA3 CNGA3 PIK3CG PIK3CG SDC1 SDC1 EEF2K EEF2K AQP8 AQP8 TRPM2 TRPM2 PDXP PDXP DUOX2 DUOX2 AQP9 AQP9 HCN4 HCN4 CIB2 CIB2 ABCC9 ABCC9 SLC6A1 SLC6A1 NT5E NT5E HDAC2 HDAC2 FOS FOS P2RX6 P2RX6 AANAT AANAT ADORA2A ADORA2A FDX1 FDX1 ENPP1 ENPP1 AKAP7 AKAP7 ASS1 ASS1 TMEM38B TMEM38B P2RX1 P2RX1 PER1 PER1 SREBF1 SREBF1 CREM CREM COL1A1 COL1A1 ENSPANP00000020409 ENSPANP00000020409 ENSPANP00000021415 ENSPANP00000021415 TMEM38A TMEM38A RAP1A RAP1A ENSPANP00000022073 ENSPANP00000022073 BSG BSG PKLR PKLR TAF1 TAF1 ENSPANP00000025300 ENSPANP00000025300 ENSPANP00000026210 ENSPANP00000026210 STAT1 STAT1 ENSPANP00000026453 ENSPANP00000026453 P2RX3 P2RX3 ENSPANP00000027212 ENSPANP00000027212 ADIPOQ ADIPOQ AQP1 AQP1 ENSPANP00000029568 ENSPANP00000029568 TRPV1 TRPV1 OXT OXT ADA ADA RAPGEF2 RAPGEF2 KDM1A KDM1A HCN2 HCN2 ASPH ASPH P2RX4 P2RX4 PDE4D PDE4D INHBB INHBB RYR2 RYR2 EZR EZR AKAP6 AKAP6 RAPGEF1 RAPGEF1 RYR3 RYR3 CITED1 CITED1 RPLP0 RPLP0 ENSPANP00000036984 ENSPANP00000036984 P2RX2 P2RX2 PAX4 PAX4 WT1 WT1 SELENON SELENON DUOX1 DUOX1 ENSPANP00000038173 ENSPANP00000038173 DMTN DMTN P2RX5 P2RX5 ENSPANP00000041865 ENSPANP00000041865 ENSPANP00000041894 ENSPANP00000041894 AREG AREG SLC8A1 SLC8A1 ENSPANP00000042482 ENSPANP00000042482 INPP5K INPP5K ENSPANP00000043438 ENSPANP00000043438 PDE2A PDE2A AKAP9 AKAP9 ENSPANP00000044155 ENSPANP00000044155 ATF1 ATF1 HSP90B1 HSP90B1 ENSPANP00000047678 ENSPANP00000047678
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
P2RY11Purinergic receptor P2Y11; Belongs to the G-protein coupled receptor 1 family. (374 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
P2RY12Purinergic receptor P2Y12. (342 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (925 aa)
ENSPANP00000000847Uncharacterized protein. (439 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
SSH1Slingshot protein phosphatase 1. (1050 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
ENSPANP00000001602RL10P_insert domain-containing protein. (279 aa)
PPARGC1BPPARG coactivator 1 beta. (1023 aa)
PDE3APhosphodiesterase. (1141 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CHEK1Checkpoint kinase 1. (480 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa)
GATA6GATA binding protein 6. (595 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (400 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (777 aa)
PANX1Pannexin; Structural component of the gap junctions and the hemichannels. (426 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (174 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (885 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
IGFBP5Insulin like growth factor binding protein 5. (272 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (969 aa)
SLC26A6Solute carrier family 26 member 6. (759 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (758 aa)
RAP1BUncharacterized protein. (184 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
XRN15'-3' exoribonuclease 1. (1707 aa)
RYR1Ryanodine receptor 1. (4842 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
ADSS2Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (392 aa)
STC1Stanniocalcin 1. (247 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1481 aa)
CPS1Carbamoyl-phosphate synthase 1. (1507 aa)
GATA1GATA binding protein 1. (413 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (608 aa)
P2RY2Purinergic receptor P2Y2; Belongs to the G-protein coupled receptor 1 family. (377 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa)
P2RY4Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family. (365 aa)
PENKProenkephalin. (267 aa)
MMP19Matrix metallopeptidase 19. (508 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
DGKQDiacylglycerol kinase. (945 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (537 aa)
P2RY6Pyrimidinergic receptor P2Y6. (328 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
SLC5A5Solute carrier family 5 member 5; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (643 aa)
LOC101014578Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (694 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
AQP8Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1475 aa)
PDXPPyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily. (300 aa)
DUOX2Dual oxidase 2. (1516 aa)
AQP9Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (297 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1116 aa)
CIB2Calcium and integrin binding family member 2. (200 aa)
ABCC9ATP binding cassette subfamily C member 9. (1549 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (503 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (357 aa)
AANATAralkylamine N-acetyltransferase. (246 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa)
FDX1Ferredoxin 1. (184 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1 (Predicted). (925 aa)
AKAP7A-kinase anchoring protein 7. (350 aa)
ASS1Uncharacterized protein. (412 aa)
TMEM38BTransmembrane protein 38B. (291 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (389 aa)
PER1Period circadian regulator 1. (1292 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
CREMcAMP responsive element modulator. (330 aa)
COL1A1Collagen type I alpha 1 chain. (1369 aa)
ENSPANP00000020409Uncharacterized protein. (375 aa)
ENSPANP00000021415Uncharacterized protein. (442 aa)
TMEM38ATransmembrane protein 38A. (257 aa)
RAP1AUncharacterized protein. (195 aa)
ENSPANP00000022073RL10P_insert domain-containing protein. (311 aa)
BSGBasigin (Ok blood group). (380 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
TAF1Transcription initiation factor TFIID subunit. (1902 aa)
ENSPANP00000025300Uncharacterized protein. (77 aa)
ENSPANP00000026210Uncharacterized protein. (136 aa)
STAT1Signal transducer and activator of transcription. (791 aa)
ENSPANP00000026453Uncharacterized protein. (128 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (398 aa)
ENSPANP00000027212RL10P_insert domain-containing protein. (165 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (275 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (296 aa)
ENSPANP00000029568Uncharacterized protein. (299 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (153 aa)
ADAA_deaminase domain-containing protein. (449 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1701 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (679 aa)
ASPHAspartate beta-hydroxylase. (762 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (404 aa)
PDE4DPhosphodiesterase. (510 aa)
INHBBInhibin subunit beta B. (407 aa)
RYR2Ryanodine receptor 2. (4951 aa)
EZREzrin. (603 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1095 aa)
RYR3Ryanodine receptor 3. (4873 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
RPLP060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (317 aa)
ENSPANP00000036984Uncharacterized protein. (107 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (496 aa)
PAX4Paired box 4. (351 aa)
WT1WT1 transcription factor. (510 aa)
SELENONSelenoprotein N. (557 aa)
DUOX1Dual oxidase 1. (1562 aa)
ENSPANP00000038173Uncharacterized protein. (113 aa)
DMTNDematin actin binding protein. (406 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (366 aa)
ENSPANP00000041865RL10P_insert domain-containing protein. (266 aa)
ENSPANP00000041894Uncharacterized protein. (718 aa)
AREGAmphiregulin. (274 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
ENSPANP00000042482Uncharacterized protein. (406 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (456 aa)
ENSPANP00000043438Uncharacterized protein. (435 aa)
PDE2APhosphodiesterase. (930 aa)
AKAP9A-kinase anchoring protein 9. (3922 aa)
ENSPANP00000044155RL10P_insert domain-containing protein. (292 aa)
ATF1Activating transcription factor 1. (270 aa)
HSP90B1Heat shock protein 90 beta family member 1. (815 aa)
ENSPANP00000047678Uncharacterized protein. (103 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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