STRINGSTRING
MTMR8 MTMR8 CALCOCO2 CALCOCO2 ENSPANP00000040214 ENSPANP00000040214 ENSPANP00000040129 ENSPANP00000040129 SESN3 SESN3 MAPK10 MAPK10 IRGM IRGM ENSPANP00000038017 ENSPANP00000038017 SPTLC1 SPTLC1 SNX32 SNX32 VPS13C VPS13C RNF41 RNF41 NEDD4 NEDD4 ENSPANP00000034045 ENSPANP00000034045 SCOC SCOC MAPK8 MAPK8 TP53 TP53 SNX5 SNX5 PAFAH1B2 PAFAH1B2 ENSPANP00000031797 ENSPANP00000031797 NRBP2 NRBP2 RAB3GAP2 RAB3GAP2 FYCO1 FYCO1 EXOC4 EXOC4 HIF1A HIF1A CAPNS1 CAPNS1 ENSPANP00000026327 ENSPANP00000026327 CYP2C8-2 CYP2C8-2 ATP13A2 ATP13A2 SNX18 SNX18 FEZ1 FEZ1 SEC22B SEC22B VPS26A VPS26A ATP6V0A1 ATP6V0A1 ATP6V1C2 ATP6V1C2 HTT HTT TSC2 TSC2 ATP6V1H ATP6V1H AMBRA1 AMBRA1 ENSPANP00000021879 ENSPANP00000021879 WAC WAC DCN DCN ENSPANP00000021245 ENSPANP00000021245 PIP4K2B PIP4K2B SIRT1 SIRT1 PIP4K2A PIP4K2A POLDIP2 POLDIP2 SMCR8 SMCR8 PHF23 PHF23 LRSAM1 LRSAM1 C9orf72 C9orf72 SNX30 SNX30 ATP6V1G1 ATP6V1G1 TSC1 TSC1 RHEB RHEB PINK1 PINK1 UBQLN4 UBQLN4 SCFD1 SCFD1 RNF31 RNF31 RUBCN RUBCN ATG14 ATG14 ENSPANP00000016954 ENSPANP00000016954 CHMP4B CHMP4B WIPI1 WIPI1 BAG3 BAG3 ERN1 ERN1 USP36 USP36 EXOC7 EXOC7 BNIP3 BNIP3 SPTLC2 SPTLC2 MTOR MTOR GPSM1 GPSM1 SMG1 SMG1 FEZ2 FEZ2 ATG5 ATG5 HDAC6 HDAC6 HSPB8 HSPB8 LARP1 LARP1 TBK1 TBK1 SNX4 SNX4 ATP6V1B2 ATP6V1B2 PIK3CA PIK3CA MOAP1 MOAP1 RUFY4 RUFY4 EXOC1 EXOC1 TMEM39B TMEM39B WDR24 WDR24 ENSPANP00000044358 ENSPANP00000044358 PIK3C3 PIK3C3 ATP6V0B ATP6V0B PRKAA2 PRKAA2 TMEM39A TMEM39A ENSPANP00000003957 ENSPANP00000003957 VPS13D VPS13D PIK3R4 PIK3R4 KIAA1324 KIAA1324 RAB3GAP1 RAB3GAP1 ATP6V1E2 ATP6V1E2 CDK5 CDK5 NPC1 NPC1 NOD1 NOD1 TIGAR TIGAR RIPK2 RIPK2 SUPT5H SUPT5H KDR KDR CLEC16A CLEC16A ATP6V0C ATP6V0C AKT1 AKT1 HMOX1 HMOX1 NOD2 NOD2 VPS35 VPS35 NUPR1 NUPR1 MAPK3 MAPK3 CLN3 CLN3 SLC25A6 SLC25A6 EHMT2 EHMT2 TRIM13 TRIM13 GAPDH GAPDH SESN2 SESN2 IL4 IL4 STING1 STING1 CDK5R1 CDK5R1 SLC25A4 SLC25A4 VDAC1 VDAC1 TBC1D25 TBC1D25 BNIP3L BNIP3L LZTS1 LZTS1 UBQLN2 UBQLN2 EXOC8 EXOC8 ENSPANP00000008508 ENSPANP00000008508 ATP6V0A2 ATP6V0A2 UVRAG UVRAG PRAF2 PRAF2 ULK1 ULK1 SNX7 SNX7 PIP4K2C PIP4K2C ATG2A ATG2A ADRB2 ADRB2 LRRK2 LRRK2 TECPR1 TECPR1 QSOX1 QSOX1 USP30 USP30 EPM2A EPM2A LACRT LACRT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTMR8Myotubularin related protein 8. (710 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (470 aa)
ENSPANP00000040214V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (107 aa)
ENSPANP00000040129Uncharacterized protein. (147 aa)
SESN3Sestrin 3. (530 aa)
MAPK10Mitogen-activated protein kinase. (467 aa)
IRGMImmunity related GTPase M. (159 aa)
ENSPANP00000038017Uncharacterized protein. (387 aa)
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (500 aa)
SNX32Sorting nexin; Involved in several stages of intracellular trafficking. (404 aa)
VPS13CVacuolar protein sorting 13 homolog C. (3754 aa)
RNF41Ring finger protein 41. (317 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1319 aa)
ENSPANP00000034045Uncharacterized protein. (322 aa)
SCOCShort coiled-coil protein. (157 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
SNX5Sorting nexin; Involved in several stages of intracellular trafficking. (405 aa)
PAFAH1B2Platelet activating factor acetylhydrolase 1b catalytic subunit 2. (229 aa)
ENSPANP00000031797Uncharacterized protein. (72 aa)
NRBP2Nuclear receptor binding protein 2. (519 aa)
RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2. (1396 aa)
FYCO1FYVE and coiled-coil domain containing 1. (1498 aa)
EXOC4Exocyst complex component 4. (974 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (832 aa)
CAPNS1Calpain small subunit 1. (391 aa)
ENSPANP00000026327SGNH_hydro domain-containing protein. (208 aa)
CYP2C8-2Uncharacterized protein. (283 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1202 aa)
SNX18Sorting nexin. (622 aa)
FEZ1Fasciculation and elongation protein zeta 1. (392 aa)
SEC22BSEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
VPS26AVPS26, retromer complex component A. (334 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (417 aa)
HTTHuntingtin. (3118 aa)
TSC2TSC complex subunit 2. (1810 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (492 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1308 aa)
ENSPANP00000021879Uncharacterized protein. (453 aa)
WACWW domain containing adaptor with coiled-coil. (653 aa)
DCNDecorin; May affect the rate of fibrils formation. (359 aa)
ENSPANP00000021245Uncharacterized protein. (157 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
SIRT1Sirtuin 1. (743 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (406 aa)
POLDIP2DNA polymerase delta interacting protein 2. (375 aa)
SMCR8SMCR8-C9orf72 complex subunit. (936 aa)
PHF23PHD finger protein 23. (403 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (723 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
SNX30Sorting nexin family member 30. (437 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
TSC1TSC complex subunit 1. (1168 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
PINK1PTEN induced kinase 1. (581 aa)
UBQLN4Ubiquilin 4. (601 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (641 aa)
RNF31Uncharacterized protein. (1072 aa)
RUBCNRubicon autophagy regulator. (986 aa)
ATG14Autophagy related 14. (510 aa)
ENSPANP00000016954Uncharacterized protein. (299 aa)
CHMP4BCharged multivesicular body protein 4B. (269 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (436 aa)
BAG3BCL2 associated athanogene 3. (575 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (977 aa)
USP36Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1123 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (735 aa)
BNIP3BCL2 interacting protein 3. (259 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (556 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
GPSM1G protein signaling modulator 1. (707 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3659 aa)
FEZ2Uncharacterized protein. (382 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
HDAC6Histone deacetylase 6. (1215 aa)
HSPB8Heat shock protein family B (small) member 8; Belongs to the small heat shock protein (HSP20) family. (196 aa)
LARP1La ribonucleoprotein domain family member 1. (1065 aa)
TBK1TANK binding kinase 1. (729 aa)
SNX4Sorting nexin 4. (450 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MOAP1Modulator of apoptosis 1. (351 aa)
RUFY4RUN and FYVE domain containing 4. (586 aa)
EXOC1Exocyst complex component 1. (901 aa)
TMEM39BTransmembrane protein 39B. (496 aa)
WDR24WD repeat domain 24. (899 aa)
ENSPANP00000044358PX domain-containing protein. (338 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (897 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (259 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
TMEM39ATransmembrane protein 39A. (488 aa)
ENSPANP00000003957Uncharacterized protein. (182 aa)
VPS13DVacuolar protein sorting 13 homolog D. (4373 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
KIAA1324KIAA1324. (893 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (989 aa)
ATP6V1E2ATPase H+ transporting V1 subunit E2. (226 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (302 aa)
NPC1NPC intracellular cholesterol transporter 1. (1277 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (549 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1315 aa)
CLEC16AC-type lectin domain containing 16A. (1053 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
HMOX1Heme oxygenase 1. (288 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1117 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (100 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CLN3Battenin. (439 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (232 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1266 aa)
TRIM13Tripartite motif containing 13. (409 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
SESN2Sestrin 2. (480 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (153 aa)
STING1Stimulator of interferon protein. (379 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (290 aa)
VDAC1Voltage dependent anion channel 1. (289 aa)
TBC1D25TBC1 domain family member 25. (688 aa)
BNIP3LBCL2 interacting protein 3 like. (219 aa)
LZTS1Leucine zipper tumor suppressor 1. (596 aa)
UBQLN2Ubiquilin 2. (624 aa)
EXOC8Exocyst complex component 8. (710 aa)
ENSPANP00000008508Uncharacterized protein. (270 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa)
UVRAGUV radiation resistance associated. (699 aa)
PRAF2Uncharacterized protein. (361 aa)
ULK1Unc-51 like autophagy activating kinase 1. (964 aa)
SNX7Sorting nexin 7. (451 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa)
ATG2AUncharacterized protein. (1932 aa)
ADRB2Adrenoceptor beta 2. (394 aa)
LRRK2Uncharacterized protein. (2479 aa)
TECPR1Tectonin beta-propeller repeat containing 1. (1165 aa)
QSOX1Sulfhydryl oxidase. (747 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
LACRTLacritin. (137 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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