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| | POLR1C | RNA polymerase I and III subunit C. (350 aa) |
| | MED21 | Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (160 aa) |
| | MAB21L1 | Mab-21 like 1. (359 aa) |
| | EIF2B3 | Eukaryotic translation initiation factor 2B subunit gamma. (453 aa) |
| | POLQ | DNA polymerase theta. (2726 aa) |
| | POLR3G | DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (223 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthetase 2. (727 aa) |
| | POLRMT | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1228 aa) |
| | POLN | DNA polymerase nu. (733 aa) |
| | FHIT | Bis(5'-adenosyl)-triphosphatase. (149 aa) |
| | POLR2K | Uncharacterized protein. (58 aa) |
| | TENT2 | Terminal nucleotidyltransferase 2. (484 aa) |
| | MB21D2 | Mab-21 domain containing 2. (491 aa) |
| | FICD | FIC domain containing. (463 aa) |
| | TENT5B | Terminal nucleotidyltransferase 5B. (425 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (117 aa) |
| | CLMP | CXADR like membrane protein. (374 aa) |
| | MAB21L2 | Mab-21 like 2. (359 aa) |
| | TENT5C | Terminal nucleotidyltransferase 5C. (391 aa) |
| | POLR2I | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa) |
| | REV3L | REV3 like, DNA directed polymerase zeta catalytic subunit. (3128 aa) |
| | YRDC | YrdC N6-threonylcarbamoyltransferase domain containing. (371 aa) |
| | CRPPA | CDP-L-ribitol pyrophosphorylase A. (451 aa) |
| | FPGT | Fucose-1-phosphate guanylyltransferase. (607 aa) |
| | NMNAT3 | Nicotinamide-nucleotide adenylyltransferase. (252 aa) |
| | REV1 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1250 aa) |
| | TENT4A | Terminal nucleotidyltransferase 4A. (736 aa) |
| | ARID3A | AT-rich interaction domain 3A. (589 aa) |
| | TRNT1 | tRNA nucleotidyl transferase 1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (439 aa) |
| | ENSPANP00000007377 | ATP_bind_3 domain-containing protein. (291 aa) |
| | POLD4 | Uncharacterized protein. (107 aa) |
| | GDPGP1 | Uncharacterized protein. (385 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (380 aa) |
| | CDS1 | Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (461 aa) |
| | MOCS3 | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (460 aa) |
| | PCYT1B | Phosphate cytidylyltransferase 1, choline, beta. (369 aa) |
| | PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1. (624 aa) |
| | POLR3B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1133 aa) |
| | POLD1 | DNA polymerase. (1107 aa) |
| | TUT1 | RRM domain-containing protein. (829 aa) |
| | PNPT1 | Polyribonucleotide nucleotidyltransferase 1. (783 aa) |
| | POLK | DNA polymerase kappa. (870 aa) |
| | ENSPANP00000009145 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa) |
| | CHRAC1 | Chromatin accessibility complex subunit 1. (131 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthetase 1. (488 aa) |
| | PRIMPOL | Primase and DNA directed polymerase. (556 aa) |
| | POLM | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (494 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2264 aa) |
| | LOC101001980 | RNA_pol_L_2 domain-containing protein. (133 aa) |
| | POLR3K | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa) |
| | OAS3 | 2'-5'-oligoadenylate synthetase 3. (1078 aa) |
| | OASL | 2'-5'-oligoadenylate synthetase like. (515 aa) |
| | POLR2E | RNA polymerase II subunit E. (210 aa) |
| | POLR2B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (370 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1152 aa) |
| | ENSPANP00000047681 | Uncharacterized protein. (67 aa) |
| | NMNAT2 | Nicotinamide nucleotide adenylyltransferase 2. (307 aa) |
| | TUT7 | Terminal uridylyl transferase 7. (1473 aa) |
| | THG1L | tRNA-histidine guanylyltransferase 1 like. (319 aa) |
| | PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2. (619 aa) |
| | TENT5A | Terminal nucleotidyltransferase 5A. (523 aa) |
| | ENSPANP00000042904 | Uncharacterized protein. (118 aa) |
| | RNGTT | Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa) |
| | PCYT1A | Phosphate cytidylyltransferase 1, choline, alpha. (380 aa) |
| | TAMM41 | Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. (441 aa) |
| | CTU2 | Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Belongs to the CTU2/NCS2 family. (551 aa) |
| | POLA1 | DNA polymerase. (1478 aa) |
| | POLR2J | RNA_pol_L_2 domain-containing protein. (152 aa) |
| | NMNAT1 | Nicotinamide-nucleotide adenylyltransferase. (279 aa) |
| | NUDT5 | Nudix hydrolase 5; Belongs to the Nudix hydrolase family. (232 aa) |
| | ENSPANP00000034980 | RNA_pol_L_2 domain-containing protein. (126 aa) |
| | ABL1 | Tyrosine-protein kinase. (1112 aa) |
| | POLR2L | RNA polymerase II subunit L. (67 aa) |
| | PAPOLA | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa) |
| | ENSPANP00000030584 | Uncharacterized protein. (97 aa) |
| | TENT4B | Terminal nucleotidyltransferase 4B. (605 aa) |
| | GMPPB | GDP-mannose pyrophosphorylase B. (387 aa) |
| | ENSPANP00000024345 | Uncharacterized protein. (198 aa) |
| | CMAS | Cytidine monophosphate N-acetylneuraminic acid synthetase. (434 aa) |
| | POLR3A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1399 aa) |
| | PAPOLG | Poly(A) polymerase gamma. (723 aa) |
| | UGP2 | UTP--glucose-1-phosphate uridylyltransferase. (517 aa) |
| | POLL | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (575 aa) |
| | DNTT | DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (510 aa) |
| | COASY | Coenzyme A synthase. (593 aa) |
| | MTPAP | Mitochondrial poly(A) polymerase. (582 aa) |
| | POLR2A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1969 aa) |
| | NANS | N-acetylneuraminate synthase. (325 aa) |
| | POLR1A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1720 aa) |
| | POLR3C | RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa) |
| | POLI | DNA polymerase iota. (737 aa) |
| | GMPPA | Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. (459 aa) |
| | UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1. (508 aa) |
| | FLAD1 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. (562 aa) |
| | POLR3F | DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa) |
| | GPHN | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (758 aa) |
| | CDS2 | Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (445 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (521 aa) |
| | KARS1 | Lysine--tRNA ligase. (647 aa) |
| | CRCP | CGRP receptor component. (148 aa) |
| | HAUS3 | HAUS augmin like complex subunit 3. (603 aa) |
| | POLG2 | DNA polymerase gamma 2, accessory subunit. (485 aa) |
| | RPAP1 | RNA polymerase II associated protein 1. (1393 aa) |
| | PCYT2 | Phosphate cytidylyltransferase 2, ethanolamine. (389 aa) |
| | CGAS | Mab-21 domain-containing protein. (522 aa) |
| | CTU1 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position; Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily. (348 aa) |
| | UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1. (522 aa) |
| | TWISTNB | TWIST neighbor. (338 aa) |
| | DKC1 | Dyskeratosis congenita 1, dyskerin (Predicted). (514 aa) |
| | POLR1B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1164 aa) |
| | TEP1 | Telomerase associated protein 1. (2621 aa) |
| | POLG | DNA polymerase gamma, catalytic subunit. (1228 aa) |
| | SELENOO | Selenoprotein O. (666 aa) |
| | POLR3H | RNA polymerase III subunit H. (204 aa) |
| | POLR2F | RNA polymerase II subunit F. (158 aa) |
| | POLR2C | RNA polymerase II subunit C. (275 aa) |
| | POLH | DNA polymerase eta. (712 aa) |
| | TUT4 | Terminal uridylyl transferase 4. (1643 aa) |
