STRINGSTRING
HNRNPD HNRNPD KCNC3 KCNC3 DIXDC1 DIXDC1 SLC25A46 SLC25A46 MDK MDK PROX1 PROX1 BCL2 BCL2 NEUROD1 NEUROD1 SPTBN2 SPTBN2 CDK5 CDK5 SCRIB SCRIB GLI1 GLI1 GNPAT GNPAT ENSPANP00000003256 ENSPANP00000003256 KLHL4 KLHL4 CNTN1 CNTN1 OTX1 OTX1 FZD4 FZD4 MTPN MTPN CLP1 CLP1 PHOX2A PHOX2A DLL1 DLL1 WNT7A WNT7A PTBP2 PTBP2 EZH2 EZH2 SCN5A SCN5A LHX5 LHX5 PTPN11 PTPN11 NANOS1 NANOS1 COQ8B COQ8B TRNP1 TRNP1 GBX2 GBX2 CDK5R2 CDK5R2 CDK5R1 CDK5R1 GART GART ATP7A ATP7A ENSPANP00000011252 ENSPANP00000011252 KIF14 KIF14 MYO16 MYO16 SEMA4C SEMA4C CBLN1 CBLN1 RPGRIP1L RPGRIP1L LRRC1 LRRC1 SSTR3 SSTR3 CKB CKB TTLL1 TTLL1 FOXC1 FOXC1 ABAT ABAT HERC1 HERC1 SEZ6L2 SEZ6L2 AARS1 AARS1 RERE RERE PDSS2 PDSS2 CRKL CRKL KNDC1 KNDC1 SSTR2 SSTR2 GLI2 GLI2 KCNC1 KCNC1 SMO SMO LMX1A LMX1A WNT1 WNT1 ATF2 ATF2 FAM205A FAM205A AGTPBP1 AGTPBP1 HSPA5 HSPA5 CRK CRK PTF1A PTF1A HOXB1 HOXB1 GDF10 GDF10 LHX1 LHX1 ZNF365 ZNF365 NEUROD2 NEUROD2 HAP1 HAP1 KAT2A KAT2A NAGLU NAGLU PTPRS PTPRS GRID2 GRID2 SERPINE2 SERPINE2 FAIM2 FAIM2 OPHN1 OPHN1 LDB1 LDB1 ENSPANP00000028630 ENSPANP00000028630 EN1 EN1 LOC101017841 LOC101017841 SEC24B SEC24B WHRN WHRN LPAR1 LPAR1 ENSPANP00000030805 ENSPANP00000030805 ATRN ATRN OGDH OGDH B4GALT2 B4GALT2 TP53 TP53 ENSPANP00000033846 ENSPANP00000033846 ABL1 ABL1 RORA RORA IGF1R IGF1R ASCL1 ASCL1 TTBK2 TTBK2 ENSPANP00000039443 ENSPANP00000039443 MECP2 MECP2 ENSPANP00000041355 ENSPANP00000041355 TTC21B TTC21B NCSTN NCSTN NRXN1 NRXN1 KLHL1 KLHL1 NAV2 NAV2 CD3E CD3E SEZ6 SEZ6 KLHL5 KLHL5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (355 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (769 aa)
DIXDC1DIX domain containing 1. (683 aa)
SLC25A46Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (418 aa)
MDKMidkine. (161 aa)
PROX1Prospero homeobox 1. (737 aa)
BCL2BCL2 apoptosis regulator. (238 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2390 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (302 aa)
SCRIBScribble planar cell polarity protein. (1661 aa)
GLI1GLI family zinc finger 1. (1106 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (680 aa)
ENSPANP00000003256Uncharacterized protein. (82 aa)
KLHL4Kelch like family member 4. (718 aa)
CNTN1Contactin 1. (1018 aa)
OTX1Orthodenticle homeobox 1. (354 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
MTPNMyotrophin. (118 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (436 aa)
PHOX2APaired like homeobox 2A. (284 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
PTBP2Polypyrimidine tract binding protein 2. (531 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
LHX5LIM homeobox 5. (402 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
NANOS1Nanos C2HC-type zinc finger 1; Belongs to the nanos family. (288 aa)
COQ8BCoenzyme Q8B. (544 aa)
TRNP1TMF1 regulated nuclear protein 1. (227 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (367 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
GARTTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
ATP7AATPase copper transporting alpha. (1487 aa)
ENSPANP00000011252G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (378 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1640 aa)
MYO16Myosin XVI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1928 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
CBLN1Cerebellin 1 precursor. (193 aa)
RPGRIP1LRPGRIP1 like. (1319 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
SSTR3Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (418 aa)
CKBCreatine kinase B; Belongs to the ATP:guanido phosphotransferase family. (383 aa)
TTLL1Tubulin tyrosine ligase like 1. (423 aa)
FOXC1Fork-head domain-containing protein. (210 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4861 aa)
SEZ6L2Seizure related 6 homolog like 2. (923 aa)
AARS1Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (968 aa)
REREArginine-glutamic acid dipeptide repeats. (1566 aa)
PDSS2Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family. (399 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
KNDC1Kinase non-catalytic C-lobe domain containing 1. (1732 aa)
SSTR2Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
GLI2GLI family zinc finger 2. (1552 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
LMX1ALIM homeobox transcription factor 1 alpha. (382 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
FAM205AFamily with sequence similarity 205 member A. (1333 aa)
AGTPBP1ATP/GTP binding protein 1. (1193 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (592 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
PTF1APancreas associated transcription factor 1a. (326 aa)
HOXB1Homeobox B1. (304 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
LHX1LIM homeobox 1. (406 aa)
ZNF365Zinc finger protein 365. (407 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
HAP1Huntingtin associated protein 1. (537 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (743 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1948 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
FAIM2Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family. (315 aa)
OPHN1Oligophrenin 1. (802 aa)
LDB1LIM domain binding 1. (411 aa)
ENSPANP00000028630Uncharacterized protein. (441 aa)
EN1Homeobox protein engrailed-like. (396 aa)
LOC101017841Uncharacterized protein. (82 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1289 aa)
WHRNWhirlin. (907 aa)
LPAR1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (353 aa)
ENSPANP00000030805Uncharacterized protein. (141 aa)
ATRNAttractin. (1367 aa)
OGDHOxoglutarate dehydrogenase. (1038 aa)
B4GALT2Beta-1,4-galactosyltransferase 2. (400 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
ENSPANP00000033846Uncharacterized protein. (542 aa)
ABL1Tyrosine-protein kinase. (1112 aa)
RORARAR related orphan receptor A. (555 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (221 aa)
TTBK2Tau tubulin kinase 2; Belongs to the intermediate filament family. (1594 aa)
ENSPANP00000039443Uncharacterized protein; Belongs to the heat shock protein 70 family. (552 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
ENSPANP00000041355Uncharacterized protein. (489 aa)
TTC21BTetratricopeptide repeat domain 21B. (1315 aa)
NCSTNNicastrin. (721 aa)
NRXN1Neurexin 1. (1446 aa)
KLHL1Kelch like family member 1. (470 aa)
NAV2Neuron navigator 2. (2452 aa)
CD3ECD3e molecule. (198 aa)
SEZ6Seizure related 6 homolog. (995 aa)
KLHL5Kelch like family member 5. (723 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
Server load: low (14%) [HD]