STRINGSTRING
HCN2 HCN2 CACNB4 CACNB4 KCNQ4 KCNQ4 KCNQ3 KCNQ3 CACHD1 CACHD1 CATSPER1 CATSPER1 KCNH3 KCNH3 PTK2B PTK2B KCNK1 KCNK1 KCNS2 KCNS2 KCNH8 KCNH8 KCNA3 KCNA3 KCNJ2 KCNJ2 CDK5 CDK5 KCNJ8 KCNJ8 KCNK9 KCNK9 CACNG6 CACNG6 KCNJ3 KCNJ3 HCN3 HCN3 HCN1 HCN1 PKD2 PKD2 KCNG2 KCNG2 KCNJ13 KCNJ13 KCNE4 KCNE4 KCNG3 KCNG3 CACNG7 CACNG7 RYR1 RYR1 KCNJ5 KCNJ5 CACNA1S CACNA1S CACNA1E CACNA1E CACNA2D3 CACNA2D3 LRRC38 LRRC38 ITGAV ITGAV KCNJ9 KCNJ9 KCNA6 KCNA6 KCNA1 KCNA1 KCNV1 KCNV1 CACNA2D4 CACNA2D4 KCNE3 KCNE3 CACNA1A CACNA1A SCN2B SCN2B KCNK6 KCNK6 KCNJ15 KCNJ15 KCNJ1 KCNJ1 KCNH1 KCNH1 KCNF1 KCNF1 KCNA5 KCNA5 KCNJ16 KCNJ16 ABCC8 ABCC8 TPCN2 TPCN2 KCNA7 KCNA7 KCNA2 KCNA2 CACNA2D2 CACNA2D2 KCNK4 KCNK4 KCNQ1 KCNQ1 KCNK13 KCNK13 HVCN1 HVCN1 CNR2 CNR2 KCNJ14 KCNJ14 KCNK12 KCNK12 GRIN2D GRIN2D KCNK5 KCNK5 KCNK17 KCNK17 KCNK16 KCNK16 KCNJ6 KCNJ6 CACNG2 CACNG2 KCNJ4 KCNJ4 ASPG ASPG CACNA1H CACNA1H GRIN2A GRIN2A HCN4 HCN4 KCNG1 KCNG1 KCNB1 KCNB1 KCNS3 KCNS3 KCNH2 KCNH2 KCND1 KCND1 LRRC55 LRRC55 KCNN2 KCNN2 GRIN2C GRIN2C KCNK18 KCNK18 CACNG5 CACNG5 CACNG4 CACNG4 CACNG1 CACNG1 KCNC1 KCNC1 TMC2 TMC2 SNAP25 SNAP25 KCNH5 KCNH5 GRIN2B GRIN2B KCNN3 KCNN3 CACNA1B CACNA1B LRRC26 LRRC26 KCNG4 KCNG4 KCNS1 KCNS1 KCNK3 KCNK3 GRIN3A GRIN3A KCNV2 KCNV2 TMC1 TMC1 KCNAB3 KCNAB3 CACNA1G CACNA1G KCNH4 KCNH4 KCNH6 KCNH6 CATSPER3 CATSPER3 KCNC3 KCNC3 KCNB2 KCNB2 KCND3 KCND3 KCNH7 KCNH7 CATSPER4 CATSPER4 CACNA1I CACNA1I KCNC4 KCNC4 KCNQ2 KCNQ2 KCND2 KCND2 CALHM1 CALHM1 TSPOAP1 TSPOAP1 NCS1 NCS1 KCNC2 KCNC2 CACNA2D1 CACNA2D1 CACNA1C CACNA1C KCNK7 KCNK7 KCNAB1 KCNAB1 CACNA1F CACNA1F KCNN1 KCNN1 ENSPANP00000029372 ENSPANP00000029372 CACNG8 CACNG8 TRPV1 TRPV1 OPRM1 OPRM1 KCNK2 KCNK2 KCNMA1 KCNMA1 KCNA10 KCNA10 CACNB1 CACNB1 CACNB2 CACNB2 CACNA1D CACNA1D GRIN1 GRIN1 KCNT2 KCNT2 CACNB3 CACNB3 LRRC52 LRRC52 KCNAB2 KCNAB2 KCNQ5 KCNQ5 KCNK10 KCNK10 KCNT1 KCNT1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (679 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (691 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (871 aa)
CACHD1Cache domain containing 1. (1245 aa)
CATSPER1Cation channel sperm associated 1. (762 aa)
KCNH3Potassium voltage-gated channel subfamily H member 3. (1083 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
KCNK1Potassium channel subfamily K member. (336 aa)
KCNS2Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family. (477 aa)
KCNH8Potassium voltage-gated channel subfamily H member 8. (1107 aa)
KCNA3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (576 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (302 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (424 aa)
KCNK9Potassium channel subfamily K member. (374 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (261 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (777 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (885 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (969 aa)
KCNG2Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (467 aa)
KCNJ13Potassium voltage-gated channel subfamily J member 13. (360 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (220 aa)
KCNG3Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family. (436 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
RYR1Ryanodine receptor 1. (4842 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2310 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1091 aa)
LRRC38Leucine rich repeat containing 38. (266 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
KCNA6Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. (529 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
KCNV1Potassium voltage-gated channel modifier subfamily V member 1; Belongs to the potassium channel family. (500 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1137 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (103 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2477 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
KCNK6Potassium channel subfamily K member. (313 aa)
KCNJ15Potassium voltage-gated channel subfamily J member 15. (375 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (420 aa)
KCNH1Potassium voltage-gated channel subfamily H member 1. (989 aa)
KCNF1Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family. (501 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa)
KCNJ16Potassium voltage-gated channel subfamily J member 16. (457 aa)
ABCC8ATP binding cassette subfamily C member 8. (1580 aa)
TPCN2Two pore segment channel 2. (752 aa)
KCNA7Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. (456 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (356 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1144 aa)
KCNK4Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (419 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
KCNK13Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (408 aa)
HVCN1Hydrogen voltage gated channel 1. (273 aa)
CNR2Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
KCNJ14Potassium voltage-gated channel subfamily J member 14. (436 aa)
KCNK12Potassium two pore domain channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (430 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1308 aa)
KCNK5Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (499 aa)
KCNK17Potassium channel subfamily K member. (403 aa)
KCNK16Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (309 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (252 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (445 aa)
ASPGAsparaginase. (628 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2352 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (945 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1116 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (513 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1159 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (647 aa)
LRRC55Leucine rich repeat containing 55. (341 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (844 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1243 aa)
KCNK18Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (383 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
TMC2Transmembrane channel-like protein. (905 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
KCNH5Potassium voltage-gated channel subfamily H member 5. (988 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (743 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2341 aa)
LRRC26Leucine rich repeat containing 26. (335 aa)
KCNG4Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (519 aa)
KCNS1Potassium voltage-gated channel subfamily S member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2. Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.1/KCNS1 sub-subfamily. (529 aa)
KCNK3Potassium channel subfamily K member. (389 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
KCNV2Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (545 aa)
TMC1Transmembrane channel-like protein. (761 aa)
KCNAB3Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (404 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2372 aa)
KCNH4Potassium voltage-gated channel subfamily H member 4. (1017 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (994 aa)
CATSPER3Cation channel sperm associated 3. (398 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (769 aa)
KCNB2Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (910 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1195 aa)
CATSPER4Cation channel sperm associated 4. (484 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2220 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (649 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (888 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
CALHM1Calcium homeostasis modulator 1. (346 aa)
TSPOAP1TSPO associated protein 1. (1875 aa)
NCS1Neuronal calcium sensor 1. (190 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
KCNK7Potassium two pore domain channel subfamily K member 7; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (287 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (419 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1961 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (543 aa)
ENSPANP00000029372IRK domain-containing protein. (206 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (380 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (455 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (428 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1285 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (511 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (679 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (960 aa)
KCNT2Potassium sodium-activated channel subfamily T member 2. (1135 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (487 aa)
LRRC52Leucine rich repeat containing 52. (342 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (415 aa)
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (951 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (543 aa)
KCNT1Potassium sodium-activated channel subfamily T member 1. (1254 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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