STRINGSTRING
GFRA4 GFRA4 SMAD6 SMAD6 MEF2C MEF2C DKK1 DKK1 LRP4 LRP4 KREMEN2 KREMEN2 ENSPANP00000034318 ENSPANP00000034318 BCOR BCOR HIF1A HIF1A ENSPANP00000025300 ENSPANP00000025300 SOST SOST SRGN SRGN RFLNB RFLNB ENPP1 ENPP1 CALCR CALCR FGF23 FGF23 SOX9 SOX9 NOTCH1 NOTCH1 KREMEN1 KREMEN1 AHSG AHSG CHSY1 CHSY1 CALCA CALCA RFLNA RFLNA VDR VDR TPH1 TPH1 GATA1 GATA1 SMAD7 SMAD7 TGFB1 TGFB1 ECM1 ECM1 SFRP1 SFRP1 BCL2 BCL2 MDK MDK LTBP3 LTBP3 PTK2B PTK2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GFRA4GDNF family receptor alpha 4. (286 aa)
SMAD6Mothers against decapentaplegic homolog. (481 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
LRP4LDL receptor related protein 4. (1906 aa)
KREMEN2Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (462 aa)
ENSPANP00000034318Uncharacterized protein. (65 aa)
BCORBCL6 corepressor. (1752 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (832 aa)
ENSPANP00000025300Uncharacterized protein. (77 aa)
SOSTSclerostin. (258 aa)
SRGNSerglycin. (153 aa)
RFLNBRefilin B. (144 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1 (Predicted). (925 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (517 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
SOX9SRY-box transcription factor 9. (509 aa)
NOTCH1Notch receptor 1. (2541 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (492 aa)
AHSGAlpha 2-HS glycoprotein. (367 aa)
CHSY1Hexosyltransferase. (802 aa)
CALCACalcitonin related polypeptide alpha. (140 aa)
RFLNARefilin A. (216 aa)
VDRVitamin D receptor. (544 aa)
TPH1Tryptophan hydroxylase 1. (491 aa)
GATA1GATA binding protein 1. (413 aa)
SMAD7Mothers against decapentaplegic homolog. (493 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ECM1Extracellular matrix protein 1. (567 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
BCL2BCL2 apoptosis regulator. (238 aa)
MDKMidkine. (161 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1301 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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