STRINGSTRING
BTG1 BTG1 CTNNB1 CTNNB1 KDF1 KDF1 FOXJ2 FOXJ2 DLL1 DLL1 WNT10B WNT10B EZH2 EZH2 MACROH2A1 MACROH2A1 CD109 CD109 AHI1 AHI1 F11R F11R VDR VDR ERRFI1 ERRFI1 ENSPANP00000007424 ENSPANP00000007424 SPRY2 SPRY2 ZFP36 ZFP36 TNFRSF1A TNFRSF1A SFN SFN KEAP1 KEAP1 GDF3 GDF3 ETV2 ETV2 XDH XDH S1PR3 S1PR3 IL20 IL20 ESRP1 ESRP1 S1PR2 S1PR2 KIAA1109 KIAA1109 ABCA12 ABCA12 IL1B IL1B LOC101009903 LOC101009903 PLCB1 PLCB1 SPRY1 SPRY1 NOTCH4 NOTCH4 ROCK2 ROCK2 CDH5 CDH5 LIF LIF MAFF MAFF FOXC1 FOXC1 BMP6 BMP6 MESP1 MESP1 BMP7 BMP7 CEBPB CEBPB NOTCH1 NOTCH1 FOXE3 FOXE3 CCND1 CCND1 KRT84 KRT84 BAD BAD AJAP1 AJAP1 CEACAM1 CEACAM1 WWTR1 WWTR1 FGF10 FGF10 GDNF GDNF APOLD1 APOLD1 PRLR PRLR ZBED2 ZBED2 COMMD5 COMMD5 ATOH1 ATOH1 FOXJ1 FOXJ1 KRAS KRAS PROC PROC HEY2 HEY2 STAT5B STAT5B ENSPANP00000041567 ENSPANP00000041567 RFX3 RFX3 ENSPANP00000040053 ENSPANP00000040053 PAX6 PAX6 BMP2 BMP2 IKBKB IKBKB ASCL1 ASCL1 ENSPANP00000038657 ENSPANP00000038657 SPRED3 SPRED3 ENSPANP00000037400 ENSPANP00000037400 TP63 TP63 ACVRL1 ACVRL1 SPRED2 SPRED2 PAX4 PAX4 YAP1 YAP1 DSPP DSPP NUMA1 NUMA1 HES5 HES5 NCOA3 NCOA3 NFE2L1 NFE2L1 ATOH8 ATOH8 TP73 TP73 STAT1 STAT1 CLDN5 CLDN5 ENSPANP00000024615 ENSPANP00000024615 SRSF6 SRSF6 CDKN1B CDKN1B SFRP4 SFRP4 GDF2 GDF2 MYCL MYCL SERPINE1 SERPINE1 PTCH2 PTCH2 ROCK1 ROCK1 PAX2 PAX2 WNT9B WNT9B ETV4 ETV4 KRT36 KRT36 MED1 MED1 MACROH2A2 MACROH2A2 NODAL NODAL VEZF1 VEZF1 TMEM100 TMEM100 VCL VCL ZEB1 ZEB1 GATA3 GATA3 FOXN1 FOXN1 TRIM16 TRIM16 PTCH1 PTCH1 ZDHHC21 ZDHHC21 AQP3 AQP3 FRZB FRZB PROM1 PROM1 ADD1 ADD1 FGF2 FGF2 REG3G REG3G KLF7 KLF7 REG3A REG3A MMP9 MMP9 SIX2 SIX2 NKX2-2 NKX2-2 ZFP36L1 ZFP36L1 OVOL2 OVOL2 SGPP1 SGPP1 JAG1 JAG1 SPRED1 SPRED1 MAFG MAFG SOX9 SOX9 CAV1 CAV1 SMO SMO ID1 ID1 BMP4 BMP4 FST FST TBX3 TBX3 OSR1 OSR1 SULT2B1 SULT2B1 GRHL2 GRHL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BTG1Uncharacterized protein. (171 aa)
CTNNB1Catenin beta 1. (781 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
FOXJ2Forkhead box J2. (574 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa)
CD109CD109 molecule. (1446 aa)
AHI1Abelson helper integration site 1. (1203 aa)
F11RF11 receptor. (299 aa)
VDRVitamin D receptor. (544 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (462 aa)
ENSPANP00000007424Anti_prolifrtn domain-containing protein. (162 aa)
SPRY2Sprouty RTK signaling antagonist 2. (338 aa)
ZFP36ZFP36 ring finger protein. (332 aa)
TNFRSF1ATNF receptor superfamily member 1A. (459 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
KEAP1Kelch like ECH associated protein 1. (624 aa)
GDF3Growth differentiation factor 3. (335 aa)
ETV2ETS variant 2. (370 aa)
XDHXanthine dehydrogenase. (1333 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
IL20Interleukin 20. (176 aa)
ESRP1Epithelial splicing regulatory protein 1. (681 aa)
S1PR2Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (353 aa)
KIAA1109KIAA1109. (5058 aa)
ABCA12ATP binding cassette subfamily A member 12. (2595 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
LOC101009903Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1122 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
NOTCH4Notch receptor 4. (2000 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
MAFFMAF bZIP transcription factor F. (164 aa)
FOXC1Fork-head domain-containing protein. (210 aa)
BMP6Bone morphogenetic protein 6. (515 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (272 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
CEBPBCCAAT/enhancer-binding protein. (344 aa)
NOTCH1Notch receptor 1. (2541 aa)
FOXE3Forkhead box E3. (318 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
KRT84Keratin 84; Belongs to the intermediate filament family. (600 aa)
BADBCL2 associated agonist of cell death. (168 aa)
AJAP1Adherens junctions associated protein 1. (410 aa)
CEACAM1Uncharacterized protein. (525 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
APOLD1Apolipoprotein L domain containing 1. (279 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (619 aa)
ZBED2Zinc finger BED-type containing 2. (218 aa)
COMMD5COMM domain containing 5. (224 aa)
ATOH1Atonal bHLH transcription factor 1. (354 aa)
FOXJ1Forkhead box J1. (421 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa. (489 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (326 aa)
STAT5BSignal transducer and activator of transcription. (791 aa)
ENSPANP00000041567C2H2-type domain-containing protein. (247 aa)
RFX3Regulatory factor X3. (766 aa)
ENSPANP00000040053Uncharacterized protein. (72 aa)
PAX6Paired box 6. (462 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (776 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (221 aa)
ENSPANP00000038657COMM domain-containing protein. (233 aa)
SPRED3Sprouty related EVH1 domain containing 3. (456 aa)
ENSPANP00000037400Uncharacterized protein. (78 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (686 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (500 aa)
SPRED2Sprouty related EVH1 domain containing 2. (432 aa)
PAX4Paired box 4. (351 aa)
YAP1Yes associated protein 1. (506 aa)
DSPPDentin sialophosphoprotein. (1013 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2127 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
NCOA3Nuclear receptor coactivator. (1418 aa)
NFE2L1Nuclear factor, erythroid 2 like 1. (772 aa)
ATOH8Atonal bHLH transcription factor 8. (346 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa)
STAT1Signal transducer and activator of transcription. (791 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (277 aa)
ENSPANP00000024615Homeobox domain-containing protein. (265 aa)
SRSF6Serine and arginine rich splicing factor 6. (344 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
SFRP4Secreted frizzled related protein 4. (368 aa)
GDF2Growth differentiation factor 2. (429 aa)
MYCLMYCL proto-oncogene, bHLH transcription factor. (394 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (429 aa)
PTCH2Patched 2. (1203 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
PAX2Paired box 2. (436 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
ETV4ETS variant 4. (484 aa)
KRT36Keratin 36; Belongs to the intermediate filament family. (491 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1548 aa)
MACROH2A2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
NODALNodal growth differentiation factor. (330 aa)
VEZF1Vascular endothelial zinc finger 1. (518 aa)
TMEM100Transmembrane protein 100. (134 aa)
VCLVinculin. (1134 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1125 aa)
GATA3GATA binding protein 3. (444 aa)
FOXN1Forkhead box N1. (648 aa)
TRIM16Uncharacterized protein. (557 aa)
PTCH1Patched 1. (1452 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
AQP3Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
FRZBFrizzled related protein. (325 aa)
PROM1Prominin 1. (864 aa)
ADD1Adducin 1. (768 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
REG3GRegenerating family member 3 gamma. (175 aa)
KLF7Kruppel like factor 7. (302 aa)
REG3ARegenerating family member 3 alpha. (175 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
SIX2SIX homeobox 2. (290 aa)
NKX2-2NK2 homeobox 2. (273 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
SGPP1Sphingosine-1-phosphate phosphatase 1. (441 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1190 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
MAFGMAF bZIP transcription factor G. (162 aa)
SOX9SRY-box transcription factor 9. (509 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (163 aa)
BMP4Bone morphogenetic protein 4, isoform 3 (Predicted). (408 aa)
FSTFollistatin. (344 aa)
TBX3T-box transcription factor 3. (743 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
SULT2B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (364 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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