Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATM | CDKN2B | ENSPANP00000010521 | ENSPANP00000022281 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Uncharacterized protein. | 0.400 |
| ATM | PTEN | ENSPANP00000010521 | ENSPANP00000020539 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.539 |
| BLK | PTEN | ENSPANP00000017575 | ENSPANP00000020539 | Tyrosine-protein kinase. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.445 |
| BTK | INPP5D | ENSPANP00000045680 | ENSPANP00000014701 | Tyrosine-protein kinase. | Inositol polyphosphate-5-phosphatase D. | 0.411 |
| BTK | LYN | ENSPANP00000045680 | ENSPANP00000004416 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.956 |
| BTK | TYROBP | ENSPANP00000045680 | ENSPANP00000045265 | Tyrosine-protein kinase. | TYRO protein tyrosine kinase binding protein. | 0.500 |
| CDKN2B | ATM | ENSPANP00000022281 | ENSPANP00000010521 | Uncharacterized protein. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.400 |
| CDKN2B | PTEN | ENSPANP00000022281 | ENSPANP00000020539 | Uncharacterized protein. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.410 |
| CTLA4 | IL10 | ENSPANP00000015007 | ENSPANP00000005405 | CD152 protein. | Interleukin 10. | 0.715 |
| IL10 | CTLA4 | ENSPANP00000005405 | ENSPANP00000015007 | Interleukin 10. | CD152 protein. | 0.715 |
| INPP5D | BTK | ENSPANP00000014701 | ENSPANP00000045680 | Inositol polyphosphate-5-phosphatase D. | Tyrosine-protein kinase. | 0.411 |
| INPP5D | LYN | ENSPANP00000014701 | ENSPANP00000004416 | Inositol polyphosphate-5-phosphatase D. | Tyrosine-protein kinase. | 0.731 |
| INPP5D | PTEN | ENSPANP00000014701 | ENSPANP00000020539 | Inositol polyphosphate-5-phosphatase D. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.909 |
| INPP5D | TYROBP | ENSPANP00000014701 | ENSPANP00000045265 | Inositol polyphosphate-5-phosphatase D. | TYRO protein tyrosine kinase binding protein. | 0.537 |
| LYN | BTK | ENSPANP00000004416 | ENSPANP00000045680 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.956 |
| LYN | INPP5D | ENSPANP00000004416 | ENSPANP00000014701 | Tyrosine-protein kinase. | Inositol polyphosphate-5-phosphatase D. | 0.731 |
| LYN | PTEN | ENSPANP00000004416 | ENSPANP00000020539 | Tyrosine-protein kinase. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.489 |
| LYN | TYROBP | ENSPANP00000004416 | ENSPANP00000045265 | Tyrosine-protein kinase. | TYRO protein tyrosine kinase binding protein. | 0.516 |
| PTEN | ATM | ENSPANP00000020539 | ENSPANP00000010521 | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.539 |
| PTEN | BLK | ENSPANP00000020539 | ENSPANP00000017575 | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | Tyrosine-protein kinase. | 0.445 |
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