STRINGSTRING
RPA1 RPA1 CHD7 CHD7 POLQ POLQ RAD54L RAD54L CHD1 CHD1 RFC5 RFC5 ASCC3 ASCC3 RECQL RECQL RUVBL1 RUVBL1 HELB HELB SLFNL1 SLFNL1 HFM1 HFM1 RFC3 RFC3 MCM9 MCM9 MCM2 MCM2 SMARCAD1 SMARCAD1 GTF2F2 GTF2F2 CHD5 CHD5 FSBP FSBP POT1 POT1 RECQL4 RECQL4 TM4SF19 TM4SF19 DSCC1 DSCC1 DHX36 DHX36 ATRX ATRX RFC4 RFC4 MCMDC2 MCMDC2 ERCC6L ERCC6L MCM7 MCM7 MCM4 MCM4 HMGA1 HMGA1 CHD9 CHD9 MCM3 MCM3 MCM5 MCM5 XRCC6 XRCC6 BLM BLM CHD8 CHD8 ERCC3 ERCC3 DHX32 DHX32 RECQL5 RECQL5 FANCM FANCM HELQ HELQ DDX1 DDX1 DHX9 DHX9 DQX1 DQX1 CHD6 CHD6 MCM6 MCM6 WRN WRN RAD54L2 RAD54L2 GINS4 GINS4 RFC2 RFC2 GINS2 GINS2 SETX SETX BRIP1 BRIP1 C17orf64 C17orf64 SUPV3L1 SUPV3L1 DNA2 DNA2 TWNK TWNK FBH1 FBH1 ASCC1 ASCC1 ENSPANP00000023587 ENSPANP00000023587 RUVBL2 RUVBL2 GINS1 GINS1 DDX3X DDX3X ASCC2 ASCC2 ENSPANP00000026851 ENSPANP00000026851 GINS3 GINS3 ENSPANP00000028599 ENSPANP00000028599 CHD4 CHD4 ENSPANP00000029043 ENSPANP00000029043 RAD51 RAD51 ENSPANP00000031378 ENSPANP00000031378 CHD2 CHD2 CHD3 CHD3 ENSPANP00000032775 ENSPANP00000032775 UPF1 UPF1 ENSPANP00000033506 ENSPANP00000033506 MCM8 MCM8 CDC45 CDC45 ENSPANP00000035496 ENSPANP00000035496 IGHMBP2 IGHMBP2 WRNIP1 WRNIP1 CHTF8 CHTF8 ERCC2 ERCC2 DDX11 DDX11 CHTF18 CHTF18 XRCC5 XRCC5 ENSPANP00000042747 ENSPANP00000042747 PIF1 PIF1 G3BP1 G3BP1 NAV2 NAV2 CHD1L CHD1L RTEL1 RTEL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (625 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
POLQDNA polymerase theta. (2726 aa)
RAD54LRAD54 like. (747 aa)
CHD1Chromodomain helicase DNA binding protein 1. (1712 aa)
RFC5Replication factor C subunit 5. (340 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2202 aa)
RECQLATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (649 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
HELBDNA helicase B. (1087 aa)
SLFNL1Schlafen like 1. (405 aa)
HFM1Helicase for meiosis 1. (1435 aa)
RFC3Replication factor C subunit 3. (356 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa)
MCM2DNA helicase; Belongs to the MCM family. (904 aa)
SMARCAD1Uncharacterized protein. (1027 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1971 aa)
FSBPUncharacterized protein. (908 aa)
POT1Protection of telomeres 1. (633 aa)
RECQL4RecQ like helicase 4. (1208 aa)
TM4SF19Uncharacterized protein. (209 aa)
DSCC1DNA replication and sister chromatid cohesion 1. (426 aa)
DHX36DEAH-box helicase 36. (1008 aa)
ATRXATRX chromatin remodeler. (2490 aa)
RFC4Replication factor C subunit 4. (345 aa)
MCMDC2Minichromosome maintenance domain containing 2. (681 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1252 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
MCM4DNA helicase; Belongs to the MCM family. (863 aa)
HMGA1Uncharacterized protein. (201 aa)
CHD9Chromodomain helicase DNA binding protein 9. (2901 aa)
MCM3DNA helicase; Belongs to the MCM family. (853 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
XRCC6X-ray repair cross complementing 6. (609 aa)
BLMBLM RecQ like helicase. (1416 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2589 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
DHX32DEAH-box helicase 32 (putative). (744 aa)
RECQL5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (991 aa)
FANCMFA complementation group M. (2050 aa)
HELQHelicase, POLQ like. (1101 aa)
DDX1DEAD-box helicase 1. (740 aa)
DHX9DExH-box helicase 9. (1275 aa)
DQX1DEAQ-box RNA dependent ATPase 1. (717 aa)
CHD6Chromodomain helicase DNA binding protein 6. (2716 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
WRNWRN RecQ like helicase. (1427 aa)
RAD54L2RAD54 like 2. (1467 aa)
GINS4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa)
RFC2Replication factor C subunit 2. (352 aa)
GINS2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa)
SETXSenataxin. (2679 aa)
BRIP1BRCA1 interacting protein C-terminal helicase 1. (1247 aa)
C17orf64Chromosome 17 open reading frame 64. (236 aa)
SUPV3L1Suv3 like RNA helicase. (765 aa)
DNA2DNA replication helicase/nuclease 2. (1061 aa)
TWNKTwinkle mtDNA helicase. (684 aa)
FBH1F-box DNA helicase 1. (1079 aa)
ASCC1Activating signal cointegrator 1 complex subunit 1. (400 aa)
ENSPANP00000023587Uncharacterized protein. (151 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (473 aa)
GINS1GINS complex subunit 1. (196 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa)
ASCC2Activating signal cointegrator 1 complex subunit 2. (819 aa)
ENSPANP00000026851Uncharacterized protein. (77 aa)
GINS3GINS complex subunit 3. (223 aa)
ENSPANP00000028599Sld5 domain-containing protein. (151 aa)
CHD4Uncharacterized protein. (1937 aa)
ENSPANP00000029043Uncharacterized protein. (86 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa)
ENSPANP00000031378Uncharacterized protein. (433 aa)
CHD2Uncharacterized protein. (1792 aa)
CHD3Chromodomain helicase DNA binding protein 3. (2049 aa)
ENSPANP00000032775Uncharacterized protein. (75 aa)
UPF1UPF1 RNA helicase and ATPase. (1129 aa)
ENSPANP00000033506Uncharacterized protein. (220 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (880 aa)
CDC45Cell division cycle 45. (598 aa)
ENSPANP00000035496Ku domain-containing protein. (513 aa)
IGHMBP2Immunoglobulin mu DNA binding protein 2. (950 aa)
WRNIP1WRN helicase interacting protein 1. (632 aa)
CHTF8Chromosome transmission fidelity factor 8. (121 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
DDX11DEAD/H-box helicase 11. (944 aa)
CHTF18Chromosome transmission fidelity factor 18. (1001 aa)
XRCC5X-ray repair cross complementing 5. (785 aa)
ENSPANP00000042747Ku domain-containing protein. (555 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (691 aa)
G3BP1G3BP stress granule assembly factor 1. (461 aa)
NAV2Neuron navigator 2. (2452 aa)
CHD1LChromodomain helicase DNA binding protein 1 like. (933 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1355 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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