STRINGSTRING
USP47 USP47 ENSPANP00000027582 ENSPANP00000027582 PTPRK PTPRK AQP1 AQP1 ENSPANP00000029710 ENSPANP00000029710 COPS9 COPS9 ENSPANP00000030957 ENSPANP00000030957 C9orf116 C9orf116 KDM1A KDM1A ENSPANP00000031871 ENSPANP00000031871 ERCC1 ERCC1 TP53 TP53 NEDD4 NEDD4 USP28 USP28 CUL4B CUL4B DDB1 DDB1 BAX BAX MFAP4 MFAP4 ENSPANP00000037027 ENSPANP00000037027 CARD16 CARD16 NFATC4 NFATC4 BAK1 BAK1 ENSPANP00000041917 ENSPANP00000041917 ENSPANP00000042030 ENSPANP00000042030 MAPK13 MAPK13 ENSPANP00000043411 ENSPANP00000043411 ST20 ST20 ENSPANP00000044332 ENSPANP00000044332 ENSPANP00000046151 ENSPANP00000046151 ENSPANP00000046380 ENSPANP00000046380 RBX1 RBX1 TMEM161A TMEM161A MMP3 MMP3 DDB2 DDB2 HYAL2 HYAL2 DHX36 DHX36 ENSPANP00000008217 ENSPANP00000008217 MYC MYC PPID PPID POLD1 POLD1 RHNO1 RHNO1 POLK POLK STK11 STK11 PTGS2 PTGS2 TP53INP1 TP53INP1 TRIAP1 TRIAP1 IMPACT IMPACT RPL26L1 RPL26L1 CDC25A CDC25A CUL4A CUL4A ATR ATR PRKCD PRKCD ENSPANP00000011993 ENSPANP00000011993 CDKN1A CDKN1A N4BP1 N4BP1 MMP2 MMP2 POLH POLH OPN5 OPN5 ATF4 ATF4 CRIP1 CRIP1 EP300 EP300 CREBBP CREBBP ERCC4 ERCC4 RHBDD1 RHBDD1 METTL3 METTL3 TUBB3 TUBB3 EIF2AK4 EIF2AK4 BMF BMF INO80 INO80 OPN1SW OPN1SW ENSPANP00000016806 ENSPANP00000016806 PCNA PCNA ZBTB1 ZBTB1 EIF2S1 EIF2S1 ENSPANP00000017205 ENSPANP00000017205 MMP9 MMP9 ACTR5 ACTR5 HYAL1 HYAL1 PBK PBK MMP1 MMP1 CHEK1 CHEK1 FBXW7 FBXW7 CASP9 CASP9 XPA XPA NOC2L NOC2L RPL26 RPL26 SIRT1 SIRT1 ENSPANP00000021624 ENSPANP00000021624 AURKB AURKB ENSPANP00000022457 ENSPANP00000022457 RUVBL2 RUVBL2 TAF1 TAF1 PARP1 PARP1 LOC101021229 LOC101021229 HYAL3 HYAL3 SDE2 SDE2 XPC XPC LOC100997213 LOC100997213 NPM1 NPM1 TIMP1 TIMP1 ENSPANP00000000945 ENSPANP00000000945 SMPD1 SMPD1 PIK3R1 PIK3R1 POLD3 POLD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa)
ENSPANP00000027582Uncharacterized protein. (344 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1471 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (296 aa)
ENSPANP00000029710Uncharacterized protein. (207 aa)
COPS9Uncharacterized protein. (57 aa)
ENSPANP00000030957Uncharacterized protein. (313 aa)
C9orf116Chromosome 9 open reading frame 116. (136 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
ENSPANP00000031871Uncharacterized protein. (249 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (323 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1319 aa)
USP28Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1139 aa)
CUL4BCullin 4B; Belongs to the cullin family. (931 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
MFAP4Microfibril associated protein 4. (278 aa)
ENSPANP00000037027Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (244 aa)
CARD16Caspase recruitment domain family member 16. (196 aa)
NFATC4Nuclear factor of activated T cells 4. (933 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
ENSPANP00000041917Zf-rbx1 domain-containing protein. (93 aa)
ENSPANP00000042030Uncharacterized protein. (348 aa)
MAPK13Mitogen-activated protein kinase. (386 aa)
ENSPANP00000043411Uncharacterized protein. (233 aa)
ST20Uncharacterized protein. (78 aa)
ENSPANP00000044332Uncharacterized protein. (242 aa)
ENSPANP00000046151Uncharacterized protein. (65 aa)
ENSPANP00000046380Uncharacterized protein. (232 aa)
RBX1RING-type domain-containing protein. (108 aa)
TMEM161ATransmembrane protein 161A. (479 aa)
MMP3Matrix metallopeptidase 3. (477 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
HYAL2Hyaluronidase. (473 aa)
DHX36DEAH-box helicase 36. (1008 aa)
ENSPANP00000008217Nucleoplasmin domain-containing protein. (283 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
PPIDUncharacterized protein. (370 aa)
POLD1DNA polymerase. (1107 aa)
RHNO1RAD9-HUS1-RAD1 interacting nuclear orphan 1. (217 aa)
POLKDNA polymerase kappa. (870 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (437 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (241 aa)
TRIAP1TP53 regulated inhibitor of apoptosis 1. (76 aa)
IMPACTImpact RWD domain protein. (320 aa)
RPL26L1Ribosomal protein L26 like 1. (145 aa)
CDC25ACell division cycle 25A. (524 aa)
CUL4ACullin 4A; Belongs to the cullin family. (763 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2630 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ENSPANP00000011993Nucleoplasmin domain-containing protein. (225 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
N4BP1NEDD4 binding protein 1. (896 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
POLHDNA polymerase eta. (712 aa)
OPN5Opsin 5; Belongs to the G-protein coupled receptor 1 family. (382 aa)
ATF4Activating transcription factor 4. (351 aa)
CRIP1LIM zinc-binding domain-containing protein. (77 aa)
EP300E1A binding protein p300. (2427 aa)
CREBBPCREB binding protein. (2442 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
RHBDD1Rhomboid domain containing 1. (316 aa)
METTL3Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa)
TUBB3Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). (765 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa)
BMFBcl2 modifying factor. (206 aa)
INO80INO80 complex ATPase subunit. (1556 aa)
OPN1SWOpsin 1, short wave sensitive. (349 aa)
ENSPANP00000016806Uncharacterized protein. (324 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
ZBTB1Zinc finger and BTB domain containing 1. (644 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
ENSPANP00000017205Uncharacterized protein. (250 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
ACTR5Actin related protein 5; Belongs to the actin family. (607 aa)
HYAL1Hyaluronidase. (435 aa)
PBKPDZ binding kinase. (335 aa)
MMP1Matrix metallopeptidase 1. (469 aa)
CHEK1Checkpoint kinase 1. (480 aa)
FBXW7F-box and WD repeat domain containing 7. (706 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (416 aa)
XPAXPA, DNA damage recognition and repair factor. (273 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (740 aa)
RPL26Ribosomal protein L26. (145 aa)
SIRT1Sirtuin 1. (743 aa)
ENSPANP00000021624BZIP domain-containing protein. (322 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (328 aa)
ENSPANP00000022457Uncharacterized protein. (208 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (473 aa)
TAF1Transcription initiation factor TFIID subunit. (1902 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
LOC10102122960S ribosomal protein L26. (145 aa)
HYAL3Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Belongs to the glycosyl hydrolase 56 family. (417 aa)
SDE2SDE2 telomere maintenance homolog. (451 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (939 aa)
LOC100997213KOW domain-containing protein. (145 aa)
NPM1Nucleophosmin 1. (294 aa)
TIMP1TIMP metallopeptidase inhibitor 1. (207 aa)
ENSPANP00000000945Uncharacterized protein. (301 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
POLD3DNA polymerase delta 3, accessory subunit. (466 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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