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TRIB2 | Tribbles pseudokinase 2. (343 aa) | ||||
MAPK8IP1 | Mitogen-activated protein kinase 8 interacting protein 1. (711 aa) | ||||
MEF2C | Myocyte enhancer factor 2C. (483 aa) | ||||
PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (813 aa) | ||||
TENM1 | Teneurin transmembrane protein 1. (2733 aa) | ||||
ENSPANP00000044784 | Aida_C2 domain-containing protein. (256 aa) | ||||
MAP4K2 | Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (854 aa) | ||||
ENSPANP00000044589 | CFC domain-containing protein. (170 aa) | ||||
ENSPANP00000044012 | Uncharacterized protein. (190 aa) | ||||
PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (452 aa) | ||||
INPP5K | Inositol polyphosphate-5-phosphatase K. (456 aa) | ||||
APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa) | ||||
DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (266 aa) | ||||
MAGED1 | MAGE family member D1. (834 aa) | ||||
IL34 | Interleukin 34. (242 aa) | ||||
MAP2K7 | Mitogen-activated protein kinase kinase 7. (446 aa) | ||||
ADAM8 | ADAM metallopeptidase domain 8. (902 aa) | ||||
ENSPANP00000040053 | Uncharacterized protein. (72 aa) | ||||
BMP2 | Bone morphogenetic protein 2. (396 aa) | ||||
ENSPANP00000039389 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (230 aa) | ||||
LOC101008770 | Uncharacterized protein. (469 aa) | ||||
ENSPANP00000038453 | J domain-containing protein. (325 aa) | ||||
ENSPANP00000037400 | Uncharacterized protein. (78 aa) | ||||
ERBB2 | Receptor protein-tyrosine kinase. (1399 aa) | ||||
ENSPANP00000036984 | Uncharacterized protein. (107 aa) | ||||
TGFA | Transforming growth factor alpha. (166 aa) | ||||
PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (746 aa) | ||||
MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (890 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) | ||||
PTPRC | Protein tyrosine phosphatase receptor type C. (1313 aa) | ||||
S100A12 | S100 calcium binding protein A12; Belongs to the S-100 family. (90 aa) | ||||
FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (995 aa) | ||||
TRIB3 | Tribbles pseudokinase 3. (385 aa) | ||||
TPD52L1 | TPD52 like 1. (221 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (624 aa) | ||||
THBS1 | Thrombospondin 1. (1175 aa) | ||||
AKAP13 | A-kinase anchoring protein 13. (2875 aa) | ||||
CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) | ||||
MIF | Macrophage migration inhibitory factor. (115 aa) | ||||
ENSPANP00000030512 | Uncharacterized protein. (55 aa) | ||||
TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (836 aa) | ||||
NTRK3 | Tyrosine-protein kinase receptor. (864 aa) | ||||
TSG101 | Tumor susceptibility 101. (392 aa) | ||||
ROBO1 | Roundabout guidance receptor 1. (1684 aa) | ||||
SRC | Tyrosine-protein kinase. (644 aa) | ||||
DAB2IP | DAB2 interacting protein. (1183 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) | ||||
DTNBP1 | Dystrobrevin binding protein 1. (350 aa) | ||||
ADIPOQ | Adiponectin, C1Q and collagen domain containing. (275 aa) | ||||
RASGRP1 | RAS guanyl releasing protein 1. (842 aa) | ||||
HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (786 aa) | ||||
ENSPANP00000023303 | Uncharacterized protein. (144 aa) | ||||
TNFSF11 | Tumor necrosis factor ligand superfamily member. (317 aa) | ||||
ENSPANP00000021062 | KH type-2 domain-containing protein. (164 aa) | ||||
LOC101002950 | Uncharacterized protein. (539 aa) | ||||
CDK12 | Cyclin dependent kinase 12. (1490 aa) | ||||
PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) | ||||
FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (680 aa) | ||||
CDK5RAP3 | CDK5 regulatory subunit associated protein 3. (541 aa) | ||||
NF1 | Neurofibromin 1. (2839 aa) | ||||
KSR1 | Kinase suppressor of ras 1. (932 aa) | ||||
PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (881 aa) | ||||
DVL2 | Dishevelled segment polarity protein 2. (736 aa) | ||||
ROR2 | Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (942 aa) | ||||
SYK | Tyrosine-protein kinase. (635 aa) | ||||
DNAJA1 | Uncharacterized protein. (397 aa) | ||||
CCL19 | C-C motif chemokine. (103 aa) | ||||
KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa) | ||||
PDE5A | Phosphodiesterase. (875 aa) | ||||
AJUBA | Ajuba LIM protein. (538 aa) | ||||
CD40 | Uncharacterized protein. (262 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa) | ||||
BMP4 | Bone morphogenetic protein 4, isoform 3 (Predicted). (408 aa) | ||||
CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) | ||||
MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) | ||||
ERN1 | Endoplasmic reticulum to nucleus signaling 1. (977 aa) | ||||
MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1818 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) | ||||
FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) | ||||
HTR2B | 5-hydroxytryptamine receptor 2B. (481 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1483 aa) | ||||
PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) | ||||
TDGF1 | Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (187 aa) | ||||
IRAK3 | Interleukin 1 receptor associated kinase 3. (596 aa) | ||||
PTPN1 | Tyrosine-protein phosphatase non-receptor type. (465 aa) | ||||
BMP7 | Bone morphogenetic protein 7. (431 aa) | ||||
EDN3 | Endothelin 3. (230 aa) | ||||
LIME1 | Uncharacterized protein. (292 aa) | ||||
CSK | Tyrosine-protein kinase. (450 aa) | ||||
MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa) | ||||
EDN1 | Endothelin 1. (211 aa) | ||||
AXIN1 | Axin 1, isoform 1 (Predicted). (867 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) | ||||
DEFB114 | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (69 aa) | ||||
NOD2 | Nucleotide binding oligomerization domain containing 2. (1117 aa) | ||||
FGD2 | FYVE, RhoGEF and PH domain containing 2. (655 aa) | ||||
STK38 | Non-specific serine/threonine protein kinase. (562 aa) | ||||
ERN2 | Endoplasmic reticulum to nucleus signaling 2. (926 aa) | ||||
AGER | Advanced glycosylation end-product specific receptor. (418 aa) | ||||
TNXB | Uncharacterized protein. (4158 aa) | ||||
PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) | ||||
SPRY1 | Sprouty RTK signaling antagonist 1. (319 aa) | ||||
PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) | ||||
SASH1 | SAM and SH3 domain containing 1. (1246 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) | ||||
ERP29 | Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (261 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) | ||||
DUSP16 | Dual specificity phosphatase 16. (662 aa) | ||||
NPPA | Natriuretic peptide A. (153 aa) | ||||
CBLC | Cbl proto-oncogene C. (465 aa) | ||||
P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (537 aa) | ||||
PTPRJ | Protein tyrosine phosphatase receptor type J. (1317 aa) | ||||
DUSP1 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa) | ||||
FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) | ||||
SPRY3 | Sprouty RTK signaling antagonist 3. (288 aa) | ||||
FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) | ||||
PDCD10 | Programmed cell death 10. (208 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1161 aa) | ||||
ENSPANP00000008773 | Uncharacterized protein. (277 aa) | ||||
PAQR3 | Progestin and adipoQ receptor family member 3. (311 aa) | ||||
DRD4 | Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (415 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1382 aa) | ||||
DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) | ||||
MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa) | ||||
FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) | ||||
TNFRSF11A | TNF receptor superfamily member 11a. (616 aa) | ||||
LRRK2 | Uncharacterized protein. (2479 aa) | ||||
AGT | Angiotensinogen; Belongs to the serpin family. (490 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) | ||||
SPRY2 | Sprouty RTK signaling antagonist 2. (338 aa) | ||||
HYAL2 | Hyaluronidase. (473 aa) | ||||
MAP3K11 | Mitogen-activated protein kinase kinase kinase. (847 aa) | ||||
SORL1 | Sortilin related receptor 1. (2194 aa) | ||||
PAK1 | Non-specific serine/threonine protein kinase. (545 aa) | ||||
DVL3 | Dishevelled segment polarity protein 3. (716 aa) | ||||
GSTP1 | Uncharacterized protein; Belongs to the GST superfamily. (246 aa) | ||||
FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1325 aa) | ||||
SH2B3 | SH2B adaptor protein 3. (570 aa) | ||||
DUSP19 | Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (217 aa) | ||||
EPGN | Epithelial mitogen. (154 aa) | ||||
RGS2 | Regulator of G protein signaling 2. (211 aa) | ||||
LOC101003314 | Uncharacterized protein. (889 aa) | ||||
EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa) | ||||
TRIB1 | Tribbles pseudokinase 1. (372 aa) | ||||
AIDA | Uncharacterized protein. (306 aa) | ||||
EPHA4 | EPH receptor A4. (986 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) | ||||
PPEF2 | Serine/threonine-protein phosphatase with EF-hands. (753 aa) | ||||
MAP3K10 | Mitogen-activated protein kinase kinase kinase. (944 aa) | ||||
NUP62 | Nucleoporin 62. (338 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) | ||||
LYN | Tyrosine-protein kinase. (512 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
ARHGEF5 | Rho guanine nucleotide exchange factor 5. (1597 aa) | ||||
FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) | ||||
ADAM9 | ADAM metallopeptidase domain 9. (819 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1210 aa) | ||||
NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (278 aa) | ||||
LAX1 | Lymphocyte transmembrane adaptor 1. (398 aa) | ||||
RGS14 | Regulator of G protein signaling 14. (572 aa) | ||||
KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) | ||||
FGFR1 | Fibroblast growth factor receptor. (853 aa) | ||||
LOC110741840 | Uncharacterized protein. (591 aa) | ||||
PLA2G1B | Phospholipase A(2). (148 aa) | ||||
SFRP2 | Secreted frizzled related protein 2. (295 aa) | ||||
SFRP1 | Secreted frizzled related protein 1. (314 aa) | ||||
HIPK3 | Homeodomain interacting protein kinase 3. (1216 aa) | ||||
NEK10 | NIMA related kinase 10. (1173 aa) | ||||
MST1R | Macrophage stimulating 1 receptor. (1399 aa) | ||||
ENSPANP00000001773 | Uncharacterized protein. (189 aa) | ||||
TAOK3 | TAO kinase 3. (898 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa) | ||||
DUSP7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa) | ||||
TMEM130 | Transmembrane protein 130. (423 aa) | ||||
HRAS | Uncharacterized protein. (189 aa) | ||||
ELANE | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (264 aa) | ||||
SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa) | ||||
IRAK1 | Interleukin 1 receptor associated kinase 1. (712 aa) | ||||
RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (259 aa) | ||||
SPRY4 | Sprouty RTK signaling antagonist 4. (322 aa) |