STRINGSTRING
AASDHPPT AASDHPPT ENSPANP00000047680 ENSPANP00000047680 ENSPANP00000047678 ENSPANP00000047678 ENSPANP00000047619 ENSPANP00000047619 ENSPANP00000047241 ENSPANP00000047241 IDH2 IDH2 ENSPANP00000046188 ENSPANP00000046188 ENSPANP00000045671 ENSPANP00000045671 MDH1 MDH1 ENSPANP00000043438 ENSPANP00000043438 ENSPANP00000042471 ENSPANP00000042471 GRHPR GRHPR FTCD FTCD UROC1 UROC1 ENSPANP00000040663 ENSPANP00000040663 D2HGDH D2HGDH PCK1 PCK1 GOT1L1 GOT1L1 ENSPANP00000038755 ENSPANP00000038755 MTRR MTRR GLUD2 GLUD2 MTHFD1 MTHFD1 ST20-MTHFS ST20-MTHFS SDHAF3 SDHAF3 ENSPANP00000034052 ENSPANP00000034052 SLC19A1 SLC19A1 OGDH OGDH OGDHL OGDHL ENSPANP00000030120 ENSPANP00000030120 PCK2 PCK2 ENSPANP00000026128 ENSPANP00000026128 ENSPANP00000025405 ENSPANP00000025405 QPRT QPRT GAD2 GAD2 ENSPANP00000023023 ENSPANP00000023023 ENSPANP00000022812 ENSPANP00000022812 ENSPANP00000022298 ENSPANP00000022298 ENSPANP00000021415 ENSPANP00000021415 GOT1 GOT1 NAGS NAGS ALDH18A1 ALDH18A1 ACLY ACLY LIPF LIPF ENSPANP00000020409 ENSPANP00000020409 GLUD1 GLUD1 PHYH PHYH SLC46A1 SLC46A1 SHMT1 SHMT1 ENSPANP00000019725 ENSPANP00000019725 ASPA ASPA FPGS FPGS ASS1 ASS1 GAD1 GAD1 ACOT8 ACOT8 L2HGDH L2HGDH ME1 ME1 OAT OAT KYNU KYNU TAT TAT DGLUCY DGLUCY DLST DLST MTHFD1L MTHFD1L ALDH5A1 ALDH5A1 GCLC GCLC GOT2 GOT2 GPT2 GPT2 GLS2 GLS2 GLS GLS MTHFD2 MTHFD2 DHFR DHFR HAL HAL KYAT3 KYAT3 MDH2 MDH2 ALDH1L1 ALDH1L1 ALDH4A1 ALDH4A1 ACSF3 ACSF3 FH FH ADHFE1 ADHFE1 MDH1B MDH1B MRPS36 MRPS36 HAAO HAAO ME2 ME2 LOC101021316 LOC101021316 ALDH1L2 ALDH1L2 ADSS2 ADSS2 ENSPANP00000005759 ENSPANP00000005759 ENSPANP00000005727 ENSPANP00000005727 ME3 ME3 ENSPANP00000005298 ENSPANP00000005298 SDHB SDHB IDH1 IDH1 NIT2 NIT2 LOC101014048 LOC101014048 KMO KMO AADAT AADAT AMDHD1 AMDHD1 MTHFD2L MTHFD2L DDO DDO GCLM GCLM PRODH2 PRODH2 SHMT2 SHMT2 ENSPANP00000000847 ENSPANP00000000847 FOLR1 FOLR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AASDHPPTAminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. (309 aa)
ENSPANP00000047680annotation not available (132 aa)
ENSPANP00000047678Uncharacterized protein. (103 aa)
ENSPANP00000047619DHFR domain-containing protein. (134 aa)
ENSPANP00000047241SHMT domain-containing protein. (426 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
ENSPANP00000046188Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (374 aa)
ENSPANP00000045671Uncharacterized protein. (321 aa)
MDH1Malate dehydrogenase. (352 aa)
ENSPANP00000043438Uncharacterized protein. (435 aa)
ENSPANP00000042471ELFV_dehydrog domain-containing protein. (174 aa)
GRHPRGlyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (358 aa)
FTCDFormimidoyltransferase cyclodeaminase. (587 aa)
UROC1Urocanate hydratase 1. (736 aa)
ENSPANP00000040663Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (443 aa)
D2HGDHD-2-hydroxyglutarate dehydrogenase. (529 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (401 aa)
ENSPANP00000038755FAD_binding_2 domain-containing protein. (247 aa)
MTRR5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (724 aa)
GLUD2ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (541 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (991 aa)
ST20-MTHFS5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (229 aa)
SDHAF3Succinate dehydrogenase complex assembly factor 3. (125 aa)
ENSPANP00000034052DHFR domain-containing protein. (132 aa)
SLC19A1Solute carrier family 19 member 1. (555 aa)
OGDHOxoglutarate dehydrogenase. (1038 aa)
OGDHLOxoglutarate dehydrogenase like. (1043 aa)
ENSPANP00000030120Uncharacterized protein. (488 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (645 aa)
ENSPANP00000026128DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (175 aa)
ENSPANP00000025405Uncharacterized protein. (909 aa)
QPRTNicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (298 aa)
GAD2Glutamate decarboxylase 2. (591 aa)
ENSPANP00000023023Uncharacterized protein. (94 aa)
ENSPANP00000022812Uncharacterized protein. (62 aa)
ENSPANP00000022298Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (266 aa)
ENSPANP00000021415Uncharacterized protein. (442 aa)
GOT1Aspartate aminotransferase. (413 aa)
NAGSN-acetylglutamate synthase. (534 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1146 aa)
LIPFLipase; Belongs to the AB hydrolase superfamily. Lipase family. (408 aa)
ENSPANP00000020409Uncharacterized protein. (375 aa)
GLUD1ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (558 aa)
PHYHUncharacterized protein. (301 aa)
SLC46A1Solute carrier family 46 member 1. (459 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa)
ENSPANP00000019725DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (170 aa)
ASPAAspartoacylase. (313 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (587 aa)
ASS1Uncharacterized protein. (412 aa)
GAD1Glutamate decarboxylase 1. (594 aa)
ACOT8Acyl-CoA thioesterase 8. (319 aa)
L2HGDHL-2-hydroxyglutarate dehydrogenase. (463 aa)
ME1Malic enzyme. (572 aa)
OATOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
KYNUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (465 aa)
TATTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (454 aa)
DGLUCYD-glutamate cyclase. (621 aa)
DLSTDihydrolipoamide S-succinyltransferase. (454 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (976 aa)
ALDH5A1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (535 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
GOT2Aspartate aminotransferase. (430 aa)
GPT2Glutamic--pyruvic transaminase 2. (565 aa)
GLS2Glutaminase 2. (602 aa)
GLSGlutaminase. (669 aa)
MTHFD2Uncharacterized protein. (350 aa)
DHFRDHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (161 aa)
HALHistidine ammonia-lyase; Belongs to the PAL/histidase family. (657 aa)
KYAT3Kynurenine aminotransferase 3. (453 aa)
MDH2Malate dehydrogenase. (338 aa)
ALDH1L110-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (905 aa)
ALDH4A1Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (563 aa)
ACSF3Acyl-CoA synthetase family member 3. (576 aa)
FHFumarate hydratase. (542 aa)
ADHFE1Fe-ADH domain-containing protein. (467 aa)
MDH1BMalate dehydrogenase 1B. (544 aa)
MRPS36Uncharacterized protein. (103 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (285 aa)
ME2Malic enzyme. (584 aa)
LOC101021316DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
ALDH1L210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
ADSS2Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa)
ENSPANP00000005759Uncharacterized protein. (194 aa)
ENSPANP00000005727DHFR domain-containing protein. (155 aa)
ME3Malic enzyme. (604 aa)
ENSPANP00000005298Uncharacterized protein. (103 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
NIT2Nitrilase family member 2. (326 aa)
LOC101014048Uncharacterized protein. (454 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (463 aa)
AADATAminoadipate aminotransferase. (421 aa)
AMDHD1Amidohydrolase domain containing 1. (427 aa)
MTHFD2LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (347 aa)
DDOD-aspartate oxidase. (381 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (274 aa)
PRODH2Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (509 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
ENSPANP00000000847Uncharacterized protein. (439 aa)
FOLR1Folate receptor alpha. (257 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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