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| | TOMM70 | Translocase of outer mitochondrial membrane 70. (608 aa) |
| | SH2D1B | SH2 domain containing 1B. (132 aa) |
| | PLSCR1 | Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (318 aa) |
| | NCR3 | Natural cytotoxicity triggering receptor 3. (201 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) |
| | CLEC6A | C-type lectin domain containing 6A. (209 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (845 aa) |
| | IRF7 | Interferon regulatory factor 7. (504 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | RBM14 | RNA binding motif protein 14. (669 aa) |
| | POLR3G | DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (223 aa) |
| | CXorf21 | Chromosome X open reading frame 21. (301 aa) |
| | USP27X | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (438 aa) |
| | KLRD1 | Killer cell lectin like receptor D1. (179 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | AIM2 | Absent in melanoma 2. (343 aa) |
| | RIOK3 | Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (519 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | CD226 | CD226 molecule. (336 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (328 aa) |
| | TRIM5 | Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (497 aa) |
| | CLNK | Cytokine dependent hematopoietic cell linker. (443 aa) |
| | LOC110742924 | AIG1-type G domain-containing protein. (307 aa) |
| | LOC101018055 | MHC_I-like_Ag-recog domain-containing protein. (255 aa) |
| | LOC100999467 | Uncharacterized protein. (430 aa) |
| | ENSPANP00000045301 | Matrin-type domain-containing protein. (256 aa) |
| | TYROBP | TYRO protein tyrosine kinase binding protein. (144 aa) |
| | MATR3 | Uncharacterized protein. (895 aa) |
| | ENSPANP00000044663 | Ig-like domain-containing protein; Belongs to the MHC class I family. (348 aa) |
| | PYDC5 | Uncharacterized protein. (107 aa) |
| | CADM1 | Cell adhesion molecule 1. (473 aa) |
| | TIRAP | TIR domain containing adaptor protein. (241 aa) |
| | ENSPANP00000042747 | Ku domain-containing protein. (555 aa) |
| | STAT5B | Signal transducer and activator of transcription. (791 aa) |
| | XRCC5 | X-ray repair cross complementing 5. (785 aa) |
| | NONO | Non-POU domain containing octamer binding. (490 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (902 aa) |
| | ENSPANP00000039524 | IGc1 domain-containing protein; Belongs to the MHC class I family. (339 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (776 aa) |
| | TRIM62 | Tripartite motif containing 62. (463 aa) |
| | IRGM | Immunity related GTPase M. (159 aa) |
| | LOC101008381 | Ig-like domain-containing protein. (518 aa) |
| | FCN2 | Ficolin 2. (313 aa) |
| | ENSPANP00000037039 | Uncharacterized protein. (555 aa) |
| | PACA-F | Ig-like domain-containing protein; Belongs to the MHC class I family. (430 aa) |
| | ENSPANP00000035496 | Ku domain-containing protein. (513 aa) |
| | LOC101011042 | Fibrinogen C-terminal domain-containing protein. (326 aa) |
| | COCH | Cochlin. (569 aa) |
| | LSM14A | LSM14A mRNA processing body assembly factor. (478 aa) |
| | AKIRIN2 | Akirin 2. (220 aa) |
| | ENSPANP00000033506 | Uncharacterized protein. (220 aa) |
| | NECTIN2 | Nectin cell adhesion molecule 2. (537 aa) |
| | LOC101002253 | C-type lectin domain-containing protein. (238 aa) |
| | LOC101007932 | MHC class I antigen; Belongs to the MHC class I family. (365 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (836 aa) |
| | TRIM41 | Tripartite motif containing 41. (631 aa) |
| | SRC | Tyrosine-protein kinase. (644 aa) |
| | ENSPANP00000028905 | RRM domain-containing protein. (449 aa) |
| | MASP1 | Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (730 aa) |
| | LAMP1 | Lysosomal associated membrane protein 1. (416 aa) |
| | ENSPANP00000027932 | MHC_I-like_Ag-recog domain-containing protein. (213 aa) |
| | ENSPANP00000025698 | DFDF domain-containing protein. (362 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (842 aa) |
| | FFAR2 | Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa) |
| | LOC103881496 | C-type lectin domain-containing protein. (189 aa) |
| | ENSPANP00000024345 | Uncharacterized protein. (198 aa) |
| | LOC101012738 | Ig-like domain-containing protein; Belongs to the MHC class I family. (365 aa) |
| | IFI35 | Interferon induced protein 35. (286 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1548 aa) |
| | MBL2 | Mannose binding lectin 2. (255 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) |
| | POLR3C | RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa) |
| | PARP9 | Poly(ADP-ribose) polymerase family member 9. (818 aa) |
| | MMP12 | Matrix metallopeptidase 12. (426 aa) |
| | LBP | Lipopolysaccharide binding protein. (481 aa) |
| | NLRC4 | NLR family CARD domain containing 4. (1024 aa) |
| | LAG3 | Lymphocyte activating 3. (525 aa) |
| | COLEC10 | Collectin subfamily member 10. (277 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | RAET1E | MHC_I_2 domain-containing protein. (254 aa) |
| | POLR3F | DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa) |
| | MAVS | Mitochondrial antiviral signaling protein. (541 aa) |
| | ZCCHC3 | Zinc finger CCHC-type containing 3. (402 aa) |
| | EREG | Epiregulin. (169 aa) |
| | POLR3D | RNA polymerase III subunit D. (397 aa) |
| | CGAS | Mab-21 domain-containing protein. (522 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (535 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4094 aa) |
| | ZNFX1 | Zinc finger NFX1-type containing 1. (1918 aa) |
| | ZBP1 | Z-DNA binding protein 1. (420 aa) |
| | ENSPANP00000013908 | Ig-like domain-containing protein; Belongs to the MHC class I family. (361 aa) |
| | CREBBP | CREB binding protein. (2442 aa) |
| | XRCC6 | X-ray repair cross complementing 6. (609 aa) |
| | EP300 | E1A binding protein p300. (2427 aa) |
| | HSP90AA1 | Heat shock protein 90 alpha family class A member 1. (831 aa) |
| | RNF185 | Ring finger protein 185. (192 aa) |
| | NLRC5 | NLR family CARD domain containing 5. (1865 aa) |
| | COLEC11 | Collectin subfamily member 11. (304 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1117 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | MASP2 | Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (683 aa) |
| | PLA2G5 | Phospholipase A(2). (138 aa) |
| | CD160 | CD160 molecule. (234 aa) |
| | SLC15A4 | Solute carrier family 15 member 4. (496 aa) |
| | HAVCR2 | Hepatitis A virus cellular receptor 2. (294 aa) |
| | STING1 | Stimulator of interferon protein. (379 aa) |
| | IFI16 | Interferon gamma inducible protein 16. (727 aa) |
| | MNDA | Myeloid cell nuclear differentiation antigen. (407 aa) |
| | FCN3 | Ficolin 3. (299 aa) |
| | TXK | Tyrosine-protein kinase. (527 aa) |
| | SH2D1A | SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa) |
| | KLRK1 | C-type lectin domain-containing protein. (216 aa) |
| | HEXIM1 | HEXIM P-TEFb complex subunit 1. (359 aa) |
| | NMI | N-myc and STAT interactor. (307 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | PSPC1 | Paraspeckle component 1. (523 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1197 aa) |
| | PQBP1 | Polyglutamine binding protein 1. (265 aa) |
| | PVR | Uncharacterized protein. (417 aa) |
| | CRTAM | Cytotoxic and regulatory T cell molecule. (393 aa) |
| | POLR3B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1133 aa) |
| | CASP6 | Caspase 6; Belongs to the peptidase C14A family. (291 aa) |
| | FCN1 | Ficolin 1. (326 aa) |
| | IRF3 | Interferon regulatory factor 3. (422 aa) |
| | PYHIN1 | Pyrin and HIN domain family member 1. (492 aa) |
| | UBE2K | Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa) |
| | TLR8 | Toll like receptor 8; Belongs to the Toll-like receptor family. (1059 aa) |
| | SLAMF6 | SLAM family member 6. (332 aa) |
| | HPX | Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa) |
| | SFPQ | Splicing factor proline and glutamine rich. (672 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (545 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
