STRINGSTRING
POLB POLB CLDN3 CLDN3 BAD BAD KCNMB1 KCNMB1 BIRC2 BIRC2 PTK2B PTK2B CYBB CYBB DBH DBH LOC101004221 LOC101004221 CBL CBL TBXA2R TBXA2R CASP8 CASP8 CHRNB2 CHRNB2 NLRP3 NLRP3 CRHBP CRHBP RGS2 RGS2 DMAP1 DMAP1 CLDN1 CLDN1 TACR1 TACR1 HMGCS2 HMGCS2 PENK PENK ST6GAL1 ST6GAL1 CPT1A CPT1A DRD4 DRD4 NR0B2 NR0B2 TYMS TYMS SPINK1 SPINK1 TP53INP1 TP53INP1 GLRA2 GLRA2 EPS8 EPS8 ITPR2 ITPR2 EHMT2 EHMT2 TUFM TUFM ADCY7 ADCY7 GOT2 GOT2 PPARA PPARA ARSA ARSA ABAT ABAT GRIN2A GRIN2A GABBR1 GABBR1 RGS19 RGS19 ADH7 ADH7 HDAC2 HDAC2 SOD1 SOD1 MGMT MGMT AVP AVP SLC23A2 SLC23A2 SLC10A1 SLC10A1 FYN FYN GRIN2B GRIN2B FGF19 FGF19 NPPC NPPC ABCB11 ABCB11 MAOB MAOB GRIN3A GRIN3A CLDN7 CLDN7 SLC2A4 SLC2A4 SREBF1 SREBF1 GATA3 GATA3 CSF3 CSF3 ENSPANP00000022457 ENSPANP00000022457 PSMD14 PSMD14 VCAM1 VCAM1 FGFR2 FGFR2 KCNC2 KCNC2 TJP1 TJP1 CLDN5 CLDN5 TH TH ADCYAP1R1 ADCYAP1R1 RGS7 RGS7 PRKCE PRKCE OGG1 OGG1 ADIPOQ ADIPOQ EIF4G1 EIF4G1 RPS6KB1 RPS6KB1 OPRM1 OPRM1 CD14 CD14 G6PD G6PD CA3 CA3 UNC79 UNC79 IGF1R IGF1R BAK1 BAK1 S100A8 S100A8 CRHR1 CRHR1 GRIN1 GRIN1 GLRA1 GLRA1 GNRH1 GNRH1 RARA RARA ENSPANP00000045671 ENSPANP00000045671 DRD2 DRD2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (370 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
BADBCL2 associated agonist of cell death. (168 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
DBHDopamine beta-hydroxylase. (620 aa)
LOC101004221Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
CBLCbl proto-oncogene. (918 aa)
TBXA2RThromboxane A2 receptor. (372 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (538 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (487 aa)
NLRP3NLR family pyrin domain containing 3. (1035 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (467 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
PENKProenkephalin. (267 aa)
ST6GAL1ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (406 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (764 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (415 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
TYMSThymidylate synthetase. (313 aa)
SPINK1Serine peptidase inhibitor, Kazal type 1. (79 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (241 aa)
GLRA2Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (822 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1266 aa)
TUFMElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (455 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
GOT2Aspartate aminotransferase. (430 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
ARSAArylsulfatase A. (448 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (945 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (951 aa)
RGS19Regulator of G protein signaling 19. (217 aa)
ADH7Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide. (394 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (503 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
MGMTO-6-methylguanine-DNA methyltransferase. (238 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (148 aa)
SLC23A2Solute carrier family 23 member 2. (650 aa)
SLC10A1Solute carrier family 10 member 1. (349 aa)
FYNTyrosine-protein kinase. (537 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
NPPCNatriuretic peptide C. (126 aa)
ABCB11ATP binding cassette subfamily B member 11. (1321 aa)
MAOBAmine oxidase. (504 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
GATA3GATA binding protein 3. (444 aa)
CSF3Colony stimulating factor 3. (207 aa)
ENSPANP00000022457Uncharacterized protein. (208 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (315 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1758 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (277 aa)
THTyrosine hydroxylase. (549 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (523 aa)
RGS7Regulator of G protein signaling 7. (487 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
OGG18-oxoguanine DNA glycosylase. (392 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (275 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1605 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (455 aa)
CD14CD14 molecule. (384 aa)
G6PDUncharacterized protein. (561 aa)
CA3Carbonic anhydrase 3; Belongs to the alpha-carbonic anhydrase family. (260 aa)
UNC79Unc-79 homolog, NALCN channel complex subunit. (2657 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
CRHR1Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. (444 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (960 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
RARARetinoic acid receptor alpha. (478 aa)
ENSPANP00000045671Uncharacterized protein. (321 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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