STRINGSTRING
NR1H2 NR1H2 AKT2 AKT2 PPARG PPARG NR1H3 NR1H3 ENSPANP00000037007 ENSPANP00000037007 NR4A3 NR4A3 MLXIPL MLXIPL ADIPOQ ADIPOQ FABP1 FABP1 IRS2 IRS2 APOC2 APOC2 PPARGC1A PPARGC1A AVP AVP PPARA PPARA PLA2G3 PLA2G3 PPARD PPARD MLYCD MLYCD IL1B IL1B APOA4 APOA4 GHSR GHSR PLIN5 PLIN5 AVPR1A AVPR1A PTGS2 PTGS2 ABCD2 ABCD2 CPT1A CPT1A ABCD1 ABCD1 LPGAT1 LPGAT1 SLC45A3 SLC45A3 APOA5 APOA5 CD74 CD74
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NR1H2Nuclear receptor subfamily 1 group H member 2. (459 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (470 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (466 aa)
ENSPANP00000037007Uncharacterized protein. (56 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (637 aa)
MLXIPLMLX interacting protein like. (880 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (275 aa)
FABP1Fatty acid binding protein 1. (127 aa)
IRS2Insulin receptor substrate 2. (1316 aa)
APOC2Proapolipoprotein C-II; Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. Belongs to the apolipoprotein C2 family. (101 aa)
PPARGC1APPARG coactivator 1 alpha. (793 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (148 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
MLYCDMalonyl-CoA decarboxylase. (493 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
APOA4Apolipoprotein A-IV; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. (417 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
PLIN5Perilipin; Belongs to the perilipin family. (462 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ABCD2ATP binding cassette subfamily D member 2. (740 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (764 aa)
ABCD1ATP binding cassette subfamily D member 1. (745 aa)
LPGAT1Lysophosphatidylglycerol acyltransferase 1. (400 aa)
SLC45A3Solute carrier family 45 member 3. (553 aa)
APOA5Apolipoprotein A-V (Predicted). (366 aa)
CD74CD74 molecule. (294 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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