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| | ALOX5AP | Arachidonate 5-lipoxygenase activating protein. (218 aa) |
| | FADS3 | Cytochrome b5 heme-binding domain-containing protein. (444 aa) |
| | RGN | Regucalcin. (299 aa) |
| | CD74 | CD74 molecule. (294 aa) |
| | HSD17B12 | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) |
| | LOC101026624 | Cytochrome b5 heme-binding domain-containing protein. (484 aa) |
| | ENSPANP00000000847 | Uncharacterized protein. (439 aa) |
| | BHMT | Betaine--homocysteine S-methyltransferase. (470 aa) |
| | HTD2 | Hydroxyacyl-thioester dehydratase type 2. (162 aa) |
| | CAD | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2225 aa) |
| | SHMT2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa) |
| | ABHD1 | Abhydrolase domain containing 1. (380 aa) |
| | OXSM | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa) |
| | FA2H | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (340 aa) |
| | SDSL | Serine dehydratase like. (329 aa) |
| | MECR | Mitochondrial trans-2-enoyl-CoA reductase. (344 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | PYCR2 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (319 aa) |
| | PLA2G1B | Phospholipase A(2). (148 aa) |
| | EDN2 | Endothelin 2. (178 aa) |
| | PER2 | Period circadian regulator 2. (1280 aa) |
| | MTHFD2L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (347 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa) |
| | THNSL2 | Threonine synthase like 2. (484 aa) |
| | KMO | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (463 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | LOC101004221 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) |
| | PECR | Peroxisomal trans-2-enoyl-CoA reductase. (303 aa) |
| | PSPH | Phosphoserine phosphatase. (225 aa) |
| | LTC4S | Leukotriene C4 synthase. (150 aa) |
| | CARNS1 | Carnosine synthase 1. (950 aa) |
| | ASNS | Asparagine synthetase [glutamine-hydrolyzing]. (561 aa) |
| | ASNSD1 | Glutamine amidotransferase type-2 domain-containing protein. (643 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | ALDH8A1 | Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (487 aa) |
| | MGST2 | Microsomal glutathione S-transferase 2. (147 aa) |
| | LIPG | Lipase G, endothelial type. (500 aa) |
| | UGDH | UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa) |
| | SCD5 | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (330 aa) |
| | SLC1A3 | Amino acid transporter. (542 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (745 aa) |
| | ENSPANP00000005727 | DHFR domain-containing protein. (155 aa) |
| | ACMSD | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (462 aa) |
| | DPYD | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa) |
| | PNPLA8 | Patatin like phospholipase domain containing 8. (782 aa) |
| | PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (758 aa) |
| | GSTP1 | Uncharacterized protein; Belongs to the GST superfamily. (246 aa) |
| | CPS1 | Carbamoyl-phosphate synthase 1. (1507 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2458 aa) |
| | LOC101021316 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa) |
| | AKR1D1 | Aldo-keto reductase family 1 member D1. (326 aa) |
| | CRABP2 | Cellular retinoic acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa) |
| | HPGDS | Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | HAAO | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (285 aa) |
| | OTC | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa) |
| | AGXT2 | Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (513 aa) |
| | HSDL1 | Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | THNSL1 | Threonine synthase like 1. (743 aa) |
| | ACSM4 | Acyl-CoA synthetase medium chain family member 4. (580 aa) |
| | PRXL2B | Peroxiredoxin like 2B. (241 aa) |
| | LDHC | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa) |
| | ACSF3 | Acyl-CoA synthetase family member 3. (576 aa) |
| | LOC101022119 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (505 aa) |
| | NAIP | NLR family apoptosis inhibitory protein. (1372 aa) |
| | PCBD2 | Pterin-4 alpha-carbinolamine dehydratase 2. (130 aa) |
| | LOC101015173 | Uncharacterized protein. (430 aa) |
| | IDO1 | Indoleamine 2,3-dioxygenase 1. (403 aa) |
| | ENOPH1 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (242 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | LOC101003421 | BZIP domain-containing protein. (371 aa) |
| | HSD17B10 | Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa) |
| | ACSBG2 | Acyl-CoA synthetase bubblegum family member 2. (666 aa) |
| | LOC101024176 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa) |
| | DHFR | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (161 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | CYP8B1 | Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (496 aa) |
| | LTA4H | Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (587 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa) |
| | OSBP | Oxysterol-binding protein; Belongs to the OSBP family. (801 aa) |
| | PAH | Phenylalanine hydroxylase. (452 aa) |
| | SDS | Serine dehydratase. (328 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | ABHD3 | Abhydrolase domain containing 3. (409 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (493 aa) |
| | AMACR | Uncharacterized protein. (382 aa) |
| | OSBPL1A | Oxysterol-binding protein; Belongs to the OSBP family. (949 aa) |
| | PLA2G5 | Phospholipase A(2). (138 aa) |
| | APIP | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa) |
| | PYCR3 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (278 aa) |
| | HACD2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (254 aa) |
| | SLC27A5 | Solute carrier family 27 member 5. (690 aa) |
| | GLS | Glutaminase. (669 aa) |
| | TMEM196 | Transmembrane protein 196. (185 aa) |
| | PRG3 | Proteoglycan 3, pro eosinophil major basic protein 2. (225 aa) |
| | GLS2 | Glutaminase 2. (602 aa) |
| | ACSM5 | Acyl-CoA synthetase medium chain family member 5. (580 aa) |
| | ACSM2B | Uncharacterized protein. (577 aa) |
| | ACSM1 | Acyl-CoA synthetase medium chain family member 1. (475 aa) |
| | ACSM3 | Acyl-CoA synthetase medium chain family member 3. (586 aa) |
| | NDUFAB1 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa) |
| | HSD17B8 | Hydroxysteroid 17-beta dehydrogenase 8. (262 aa) |
| | HSD3B7 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. (369 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | ADI1 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa) |
| | CBS | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (565 aa) |
| | LOC101009400 | Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (474 aa) |
| | GOT2 | Aspartate aminotransferase. (430 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein. (326 aa) |
| | LOC101012978 | Uncharacterized protein. (401 aa) |
| | DECR2 | Uncharacterized protein. (265 aa) |
| | MCAT | Malonyl-CoA-acyl carrier protein transacylase. (390 aa) |
| | ELOVL2 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (296 aa) |
| | EDN1 | Endothelin 1. (211 aa) |
| | ABAT | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa) |
| | PLA2G10 | Phospholipase A(2). (165 aa) |
| | GATM | Glycine amidinotransferase. (423 aa) |
| | SLC27A2 | Solute carrier family 27 member 2. (620 aa) |
| | HACD3 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (400 aa) |
| | GSTM4 | Glutathione S-transferase. (218 aa) |
| | OSBPL2 | Oxysterol-binding protein; Belongs to the OSBP family. (480 aa) |
| | ALDH1A3 | Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (457 aa) |
| | PTGIS | Prostaglandin I2 synthase; Belongs to the cytochrome P450 family. (493 aa) |
| | LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa) |
| | ELOVL7 | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa) |
| | ABCD3 | ATP binding cassette subfamily D member 3. (659 aa) |
| | MTHFD1L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (976 aa) |
| | LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa) |
| | MGLL | Monoglyceride lipase. (313 aa) |
| | ELOVL4 | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa) |
| | LGSN | Lengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (507 aa) |
| | MRI1 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (369 aa) |
| | PLOD3 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (737 aa) |
| | ENSPANP00000015577 | Uncharacterized protein. (248 aa) |
| | PTGDS | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (190 aa) |
| | AASS | Aminoadipate-semialdehyde synthase. (925 aa) |
| | TMED8 | Transmembrane p24 trafficking protein family member 8. (326 aa) |
| | NOXRED1 | NADP dependent oxidoreductase domain containing 1. (359 aa) |
| | KYNU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (465 aa) |
| | UROS | Uroporphyrinogen III synthase. (265 aa) |
| | FADS6 | Fatty acid desaturase 6. (223 aa) |
| | ARMC7 | Armadillo repeat containing 7. (198 aa) |
| | FASN | Fatty acid synthase. (2510 aa) |
| | PLA2G4F | Phospholipase A2. (849 aa) |
| | GGT5 | Gamma-glutamyltransferase 5. (582 aa) |
| | OAT | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa) |
| | HAO1 | Hydroxyacid oxidase 1. (370 aa) |
| | ACSS1 | Acetyl-coenzyme A synthetase. (688 aa) |
| | UPB1 | Beta-ureidopropionase 1. (386 aa) |
| | GGT1 | Uncharacterized protein. (566 aa) |
| | SCP2 | Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa) |
| | LOC101014452 | Uncharacterized protein. (455 aa) |
| | DAGLB | Diacylglycerol lipase beta. (712 aa) |
| | NLRC4 | NLR family CARD domain containing 4. (1024 aa) |
| | ACOT8 | Acyl-CoA thioesterase 8. (319 aa) |
| | MTR | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1268 aa) |
| | CBR4 | Carbonyl reductase 4. (237 aa) |
| | PLP1 | Proteolipid protein 1. (277 aa) |
| | GLUL | Glutamate-ammonia ligase; Belongs to the glutamine synthetase family. (369 aa) |
| | LOC101026757 | Cytochrome P450 family 3 subfamily A member 4. (503 aa) |
| | ABCB11 | ATP binding cassette subfamily B member 11. (1321 aa) |
| | GAD1 | Glutamate decarboxylase 1. (594 aa) |
| | ENSPANP00000018669 | Uncharacterized protein. (92 aa) |
| | OSBPL6 | Oxysterol-binding protein; Belongs to the OSBP family. (959 aa) |
| | ASS1 | Uncharacterized protein. (412 aa) |
| | HACD4 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (232 aa) |
| | ALDH1A1 | Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (513 aa) |
| | PSAT1 | Phosphoserine aminotransferase. (370 aa) |
| | PTGES2 | Prostaglandin E synthase 2; Belongs to the GST superfamily. (377 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | SRR | Serine racemase. (339 aa) |
| | GGT6 | Gamma-glutamyltransferase 6. (499 aa) |
| | ALOX15 | Arachidonate 15-lipoxygenase. (662 aa) |
| | LOC101012580 | Uncharacterized protein. (672 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (663 aa) |
| | ALOX12B | Arachidonate 12-lipoxygenase, 12R type. (701 aa) |
| | ENSPANP00000019725 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (170 aa) |
| | SHMT1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa) |
| | WDR37 | WD repeat domain 37. (495 aa) |
| | OLAH | Oleoyl-ACP hydrolase. (265 aa) |
| | HACD1 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (288 aa) |
| | OSBPL7 | Oxysterol-binding protein; Belongs to the OSBP family. (842 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) |
| | GLUD1 | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (558 aa) |
| | PCBD1 | Pterin-4 alpha-carbinolamine dehydratase 1. (104 aa) |
| | ENSPANP00000020409 | Uncharacterized protein. (375 aa) |
| | ASAH2 | Neutral ceramidase. (780 aa) |
| | ENSPANP00000020681 | Uncharacterized protein. (162 aa) |
| | LOC101023648 | Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa) |
| | ACLY | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1146 aa) |
| | ALDH18A1 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa) |
| | NAGS | N-acetylglutamate synthase. (534 aa) |
| | GOT1 | Aspartate aminotransferase. (413 aa) |
| | SCD | Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa) |
| | ELOVL3 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa) |
| | ENSPANP00000021415 | Uncharacterized protein. (442 aa) |
| | LIPC | Lipase C, hepatic type. (500 aa) |
| | RBP1 | Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (197 aa) |
| | CYP2C8 | Cytochrome P450 family 2 subfamily C member 8; Belongs to the cytochrome P450 family. (490 aa) |
| | ENSPANP00000022812 | Uncharacterized protein. (62 aa) |
| | GAD2 | Glutamate decarboxylase 2. (591 aa) |
| | ENSPANP00000023551 | Uncharacterized protein. (139 aa) |
| | FADS2 | Fatty acid desaturase 2. (444 aa) |
| | PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (574 aa) |
| | PCCB | Propionyl-CoA carboxylase subunit beta. (570 aa) |
| | ELOVL1 | Elongation of very long chain fatty acids protein. (286 aa) |
| | FADS1 | Acyl-CoA (8-3)-desaturase; Isoform 1: Acts as a front-end fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 5 located between a preexisting double bond and the carboxyl end of the fatty acyl chain. Involved in biosynthesis of highly unsaturated fatty acids (HUFA) from the essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) precursors. Specifically, desaturates dihomo-gamma-linoleoate (DGLA) (20:3n-6) and eicosatetraenoate (ETA) (20:4n-3) to generate arachidonate (AA) (20:4n-6) and eicosapent [...] (501 aa) |
| | ENSPANP00000025405 | Uncharacterized protein. (909 aa) |
| | GSTM1 | Glutathione S-transferase mu 1; Belongs to the GST superfamily. (246 aa) |
| | ENSPANP00000026052 | Aminotran_5 domain-containing protein. (172 aa) |
| | ENSPANP00000026128 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (175 aa) |
| | ENSPANP00000026233 | Uncharacterized protein. (288 aa) |
| | BCAT1 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (462 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1857 aa) |
| | GAMT | Guanidinoacetate N-methyltransferase. (268 aa) |
| | ENSPANP00000028169 | Uncharacterized protein. (361 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | BCAT2 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (434 aa) |
| | ENSPANP00000029921 | PNP_UDP_1 domain-containing protein. (192 aa) |
| | MGST3 | Microsomal glutathione S-transferase 3. (166 aa) |
| | ACOT7 | Acyl-CoA thioesterase 7. (383 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | CTH | Cystathionine gamma-lyase. (430 aa) |
| | GATD1 | Glutamine amidotransferase like class 1 domain containing 1. (234 aa) |
| | SUGCT | Succinyl-CoA:glutarate-CoA transferase. (470 aa) |
| | MIF | Macrophage migration inhibitory factor. (115 aa) |
| | LOC101024697 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (500 aa) |
| | BAAT | Bile acid-CoA:amino acid N-acyltransferase. (418 aa) |
| | PYCR1 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (352 aa) |
| | ASL | Argininosuccinate lyase. (464 aa) |
| | ENSPANP00000033648 | S5A_REDUCTASE domain-containing protein. (248 aa) |
| | ENSPANP00000034052 | DHFR domain-containing protein. (132 aa) |
| | TECR | S5A_REDUCTASE domain-containing protein. (315 aa) |
| | QKI | QKI, KH domain containing RNA binding. (342 aa) |
| | TBXAS1 | Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (580 aa) |
| | PTGS1 | Prostaglandin-endoperoxide synthase 1. (632 aa) |
| | MTHFD1 | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (991 aa) |
| | ENSPANP00000036990 | Uncharacterized protein. (239 aa) |
| | GLUD2 | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (541 aa) |
| | PHGDH | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (559 aa) |
| | MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (724 aa) |
| | LOC100997115 | Glutathione S-transferase. (218 aa) |
| | GPX4 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (233 aa) |
| | GOT1L1 | Glutamic-oxaloacetic transaminase 1 like 1. (401 aa) |
| | ENSPANP00000039320 | Glutathione S-transferase. (220 aa) |
| | TECRL | Trans-2,3-enoyl-CoA reductase like. (363 aa) |
| | HNF1A | HNF1 homeobox A. (662 aa) |
| | ENSPANP00000040462 | Lyase_1 domain-containing protein. (134 aa) |
| | ALDH1A2 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (540 aa) |
| | LOC101020588 | Uncharacterized protein. (519 aa) |
| | OSBPL3 | Oxysterol-binding protein; Belongs to the OSBP family. (887 aa) |
| | ILVBL | IlvB acetolactate synthase like; Belongs to the TPP enzyme family. (635 aa) |
| | ENSPANP00000042471 | ELFV_dehydrog domain-containing protein. (174 aa) |
| | ENSPANP00000042473 | Uncharacterized protein. (270 aa) |
| | ENSPANP00000043438 | Uncharacterized protein. (435 aa) |
| | GGT7 | Gamma-glutamyltransferase 7. (664 aa) |
| | ENSPANP00000044012 | Uncharacterized protein. (190 aa) |
| | PTGES | Prostaglandin E synthase. (152 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2389 aa) |
| | ALOXE3 | Arachidonate lipoxygenase 3. (868 aa) |
| | CYP27A1 | Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (542 aa) |
| | ENSPANP00000045671 | Uncharacterized protein. (321 aa) |
| | DEGS1 | Delta 4-desaturase, sphingolipid 1. (323 aa) |
| | LIPH | Lipase H. (451 aa) |
| | MTAP | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (333 aa) |
| | ENSPANP00000046188 | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (374 aa) |
| | ENSPANP00000046292 | Aminotran_5 domain-containing protein. (341 aa) |
| | ENSPANP00000046298 | Aminotran_5 domain-containing protein. (376 aa) |
| | DHRS9 | Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (378 aa) |
| | AKR1A1 | Aldo-keto reductase family 1 member A1. (326 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | LOC101009375 | Uncharacterized protein; Belongs to the peptidase C14A family. (352 aa) |
| | ENSPANP00000047241 | SHMT domain-containing protein. (426 aa) |
| | ENSPANP00000047619 | DHFR domain-containing protein. (134 aa) |
| | ENSPANP00000047671 | Uncharacterized protein. (210 aa) |
| | ENSPANP00000047678 | Uncharacterized protein. (103 aa) |
| | ENSPANP00000047680 | annotation not available (132 aa) |
