STRINGSTRING
ENSPANP00000000333 ENSPANP00000000333 CATSPER3 CATSPER3 MYOC MYOC FAM20C FAM20C C3 C3 PTK2B PTK2B PCSK4 PCSK4 BCL2 BCL2 APP APP ELSPBP1 ELSPBP1 PDE3A PDE3A TMEM79 TMEM79 PTH1R PTH1R B4GALT6 B4GALT6 YTHDF2 YTHDF2 TDRD10 TDRD10 EPO EPO GDF11 GDF11 TGFB1 TGFB1 TUSC2 TUSC2 ANGPTL8 ANGPTL8 CTNNB1 CTNNB1 SPTBN4 SPTBN4 SLC26A6 SLC26A6 DEFB1 DEFB1 NTN4 NTN4 SLC26A3 SLC26A3 EPHA8 EPHA8 WDR77 WDR77 LGI4 LGI4 SCLT1 SCLT1 AKR1B1 AKR1B1 IL21 IL21 AXL AXL EDNRA EDNRA CEBPA CEBPA SRRM4 SRRM4 FEV FEV CFTR CFTR GATA2 GATA2 HOXA5 HOXA5 BHLHA15 BHLHA15 IL15 IL15 MTHFSD MTHFSD FARP2 FARP2 KLF2 KLF2 CATSPERZ CATSPERZ REN REN SLC22A14 SLC22A14 FZD5 FZD5 TYMS TYMS EFCAB9 EFCAB9 RND1 RND1 SPINK1 SPINK1 RHEX RHEX TRIP13 TRIP13 IQCF5 IQCF5 CCR6 CCR6 ROPN1B ROPN1B TUT4 TUT4 ROPN1 ROPN1 FBXO5 FBXO5 ANKS1A ANKS1A SLC26A8 SLC26A8 MTCH1 MTCH1 CX3CL1 CX3CL1 TDRD6 TDRD6 CBFB CBFB PLA2G3 PLA2G3 SOX10 SOX10 DMC1 DMC1 SOX8 SOX8 BRD1 BRD1 EDN1 EDN1 PLA2G10 PLA2G10 GLDN GLDN FEM1B FEM1B SOX18 SOX18 FAM210B FAM210B B4GALT5 B4GALT5 KCNB1 KCNB1 FLVCR1 FLVCR1 KDR KDR ZBTB7A ZBTB7A IHH IHH TDRD15 TDRD15 CATSPERD CATSPERD EREG EREG FOXA1 FOXA1 VSX1 VSX1 REC8 REC8 CABYR CABYR IQCF1 IQCF1 RB1 RB1 FGG FGG BFSP2 BFSP2 ACTL6B ACTL6B CCL19 CCL19 SCARF1 SCARF1 AGRN AGRN PMP22 PMP22 PLD6 PLD6 GATA3 GATA3 HOXB13 HOXB13 RET RET C1QL1 C1QL1 KCNIP2 KCNIP2 CDC25B CDC25B RUNX2 RUNX2 BRCA2 BRCA2 BFSP1 BFSP1 SIX3 SIX3 CATSPER2 CATSPER2 NRCAM NRCAM ROPN1L ROPN1L HIF1A HIF1A LOC101003477 LOC101003477 GHRHR GHRHR RPS6KA2 RPS6KA2 HES5 HES5 ENSPANP00000031440 ENSPANP00000031440 KDM1A KDM1A ENSPANP00000032114 ENSPANP00000032114 G6PD G6PD NR4A2 NR4A2 CATSPER4 CATSPER4 EPAS1 EPAS1 L3MBTL3 L3MBTL3 BSPH1 BSPH1 MAEA MAEA ABHD2 ABHD2 PTBP3 PTBP3 ERCC2 ERCC2 ASCL1 ASCL1 MECP2 MECP2 RFX3 RFX3 TDRD1 TDRD1 CNTN2 CNTN2 TDRKH TDRKH ENSPANP00000044042 ENSPANP00000044042 LHX6 LHX6 TDRD5 TDRD5 BAP1 BAP1 TUT7 TUT7 BTK BTK PABPC1L PABPC1L ENSPANP00000046779 ENSPANP00000046779
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPANP00000000333Aldo_ket_red domain-containing protein. (268 aa)
CATSPER3Cation channel sperm associated 3. (398 aa)
MYOCMyocilin. (499 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (584 aa)
C3Complement C3. (1663 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (742 aa)
BCL2BCL2 apoptosis regulator. (238 aa)
APPAmyloid beta precursor protein. (770 aa)
ELSPBP1Epididymal sperm binding protein 1. (223 aa)
PDE3APhosphodiesterase. (1141 aa)
TMEM79Transmembrane protein 79. (394 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (593 aa)
B4GALT6Beta-1,4-galactosyltransferase 6. (382 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (447 aa)
TDRD10Tudor domain containing 10. (366 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
GDF11Growth differentiation factor 11. (406 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TUSC2Tumor suppressor 2, mitochondrial calcium regulator. (110 aa)
ANGPTL8Angiopoietin like 8. (198 aa)
CTNNB1Catenin beta 1. (781 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (2565 aa)
SLC26A6Solute carrier family 26 member 6. (759 aa)
DEFB1Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. (68 aa)
NTN4Netrin 4. (628 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (758 aa)
EPHA8EPH receptor A8. (1005 aa)
WDR77WD repeat domain 77. (342 aa)
LGI4Leucine rich repeat LGI family member 4. (524 aa)
SCLT1Sodium channel and clathrin linker 1. (717 aa)
AKR1B1Aldo-keto reductase family 1 member B. (316 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
CEBPACCAAT/enhancer-binding protein. (349 aa)
SRRM4Serine/arginine repetitive matrix 4. (615 aa)
FEVFEV transcription factor, ETS family member. (238 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1481 aa)
GATA2GATA binding protein 2. (480 aa)
HOXA5Homeobox A5 (Predicted). (270 aa)
BHLHA15Basic helix-loop-helix family member a15. (193 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (177 aa)
MTHFSDMethenyltetrahydrofolate synthetase domain containing. (383 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1032 aa)
KLF2Kruppel like factor 2. (356 aa)
CATSPERZCatsper channel auxiliary subunit zeta. (200 aa)
RENRenin; Belongs to the peptidase A1 family. (433 aa)
SLC22A14Solute carrier family 22 member 14. (610 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
TYMSThymidylate synthetase. (313 aa)
EFCAB9EF-hand calcium binding domain 9. (199 aa)
RND1Rho family GTPase 1. (232 aa)
SPINK1Serine peptidase inhibitor, Kazal type 1. (79 aa)
RHEXRegulator of hemoglobinization and erythroid cell expansion. (178 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa)
IQCF5IQ motif containing F5. (148 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (374 aa)
ROPN1BUncharacterized protein. (212 aa)
TUT4Terminal uridylyl transferase 4. (1643 aa)
ROPN1Uncharacterized protein. (212 aa)
FBXO5F-box protein 5. (448 aa)
ANKS1AAnkyrin repeat and sterile alpha motif domain containing 1A. (1151 aa)
SLC26A8Testis anion transporter 1. (968 aa)
MTCH1Mitochondrial carrier 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (389 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (402 aa)
TDRD6Tudor domain containing 6. (2097 aa)
CBFBCore-binding factor subunit beta. (187 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
SOX10SRY-box transcription factor 10. (377 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (340 aa)
SOX8SRY-box transcription factor 8. (446 aa)
BRD1Bromodomain containing 1. (1058 aa)
EDN1Endothelin 1. (211 aa)
PLA2G10Phospholipase A(2). (165 aa)
GLDNGliomedin. (551 aa)
FEM1BFem-1 homolog B. (627 aa)
SOX18SRY-box transcription factor 18. (384 aa)
FAM210BFamily with sequence similarity 210 member B. (192 aa)
B4GALT5Beta-1,4-galactosyltransferase 5. (388 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (555 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1315 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (584 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
TDRD15Tudor domain containing 15. (1935 aa)
CATSPERDCation channel sperm associated auxiliary subunit delta. (741 aa)
EREGEpiregulin. (169 aa)
FOXA1Forkhead box A1. (470 aa)
VSX1Visual system homeobox 1. (365 aa)
REC8REC8 meiotic recombination protein. (565 aa)
CABYRCalcium binding tyrosine phosphorylation regulated. (487 aa)
IQCF1IQ motif containing F1. (205 aa)
RB1RB transcriptional corepressor 1. (889 aa)
FGGFibrinogen gamma chain. (437 aa)
BFSP2Beaded filament structural protein 2; Belongs to the intermediate filament family. (415 aa)
ACTL6BActin like 6B; Belongs to the actin family. (426 aa)
CCL19C-C motif chemokine. (103 aa)
SCARF1Scavenger receptor class F member 1. (830 aa)
AGRNAgrin. (2077 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
PLD6Phospholipase D family member 6. (252 aa)
GATA3GATA binding protein 3. (444 aa)
HOXB13Homeobox B13. (288 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
C1QL1Complement C1q like 1. (258 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (285 aa)
CDC25BCell division cycle 25B. (570 aa)
RUNX2RUNX family transcription factor 2. (611 aa)
BRCA2BRCA2 DNA repair associated. (3430 aa)
BFSP1Beaded filament structural protein 1; Belongs to the intermediate filament family. (627 aa)
SIX3SIX homeobox 3. (353 aa)
CATSPER2Ion_trans domain-containing protein. (534 aa)
NRCAMNeuronal cell adhesion molecule. (1304 aa)
ROPN1LRhophilin associated tail protein 1 like. (230 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (832 aa)
LOC101003477G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family. (694 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (468 aa)
RPS6KA2Ribosomal protein S6 kinase. (741 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
ENSPANP00000031440Ion_trans domain-containing protein. (186 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
ENSPANP00000032114Aldo_ket_red domain-containing protein. (259 aa)
G6PDUncharacterized protein. (561 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (580 aa)
CATSPER4Cation channel sperm associated 4. (484 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (780 aa)
BSPH1Binder of sperm protein homolog 1. (115 aa)
MAEAMacrophage erythroblast attacher. (421 aa)
ABHD2Abhydrolase domain containing 2. (463 aa)
PTBP3Polypyrimidine tract binding protein 3. (558 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (221 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
RFX3Regulatory factor X3. (766 aa)
TDRD1Tudor domain containing 1. (1190 aa)
CNTN2Contactin 2. (1084 aa)
TDRKHTudor and KH domain containing. (596 aa)
ENSPANP00000044042Aldo_ket_red domain-containing protein. (300 aa)
LHX6LIM homeobox 6. (435 aa)
TDRD5Tudor domain containing 5. (1007 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (736 aa)
TUT7Terminal uridylyl transferase 7. (1473 aa)
BTKTyrosine-protein kinase. (659 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (622 aa)
ENSPANP00000046779DUF1279 domain-containing protein. (164 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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