STRINGSTRING
YIPF6 YIPF6 FGF10 FGF10 ENSPANP00000000847 ENSPANP00000000847 DNAAF1 DNAAF1 BCL2 BCL2 PRDM1 PRDM1 PDX1 PDX1 SFRP1 SFRP1 NKX2-6 NKX2-6 SFRP2 SFRP2 NIPBL NIPBL CCDC39 CCDC39 GLI1 GLI1 SOX17 SOX17 GATA6 GATA6 PKDCC PKDCC CLMP CLMP TGFB1 TGFB1 TGFB2 TGFB2 CTNNB1 CTNNB1 FOXF1 FOXF1 WNT5A WNT5A CXCL8 CXCL8 TGFBR2 TGFBR2 C1GALT1 C1GALT1 CLDN18 CLDN18 AHI1 AHI1 IFT172 IFT172 GATA4 GATA4 COL3A1 COL3A1 CPS1 CPS1 BBS7 BBS7 WNT11 WNT11 HOXA5 HOXA5 OTC OTC ALX4 ALX4 HMGCS2 HMGCS2 EDNRB EDNRB HLX HLX MIXL1 MIXL1 KLF5 KLF5 FZD5 FZD5 TYMS TYMS DCHS1 DCHS1 KCNQ1 KCNQ1 TCF21 TCF21 EPB41L5 EPB41L5 VPS52 VPS52 SPDEF SPDEF SALL1 SALL1 SOX10 SOX10 PKD1 PKD1 RBPMS2 RBPMS2 SMAD3 SMAD3 PTK6 PTK6 CHD8 CHD8 IL6ST IL6ST HOXD13 HOXD13 SCT SCT IHH IHH EXT1 EXT1 PDGFC PDGFC TIGAR TIGAR NOTCH1 NOTCH1 FOXL1 FOXL1 TGFB3 TGFB3 CRKL CRKL CCDC40 CCDC40 GLI2 GLI2 SMO SMO SAV1 SAV1 BMP4 BMP4 DACT1 DACT1 OVOL2 OVOL2 NKX2-2 NKX2-2 SHH SHH SIX2 SIX2 RB1 RB1 NKX3-2 NKX3-2 KIT KIT ASS1 ASS1 FOXE1 FOXE1 PCSK5 PCSK5 RET RET NODAL NODAL ENSPANP00000020409 ENSPANP00000020409 TBX2 TBX2 PYY PYY CCDC103 CCDC103 HOXA13 HOXA13 ENSPANP00000021415 ENSPANP00000021415 FGFR2 FGFR2 FGF9 FGF9 ACVR2B ACVR2B STRA6 STRA6 GATA5 GATA5 HIF1A HIF1A PERCC1 PERCC1 MEGF8 MEGF8 SRC SRC LGR4 LGR4 ENSPANP00000029568 ENSPANP00000029568 ADA ADA CBFA2T2 CBFA2T2 SHOX2 SHOX2 EPHB3 EPHB3 RARB RARB COBL COBL YAP1 YAP1 SMAD2 SMAD2 TP63 TP63 NKX2-3 NKX2-3 GLI3 GLI3 ASCL1 ASCL1 ALDH1A2 ALDH1A2 ID2 ID2 CCKBR CCKBR CDX2 CDX2 ENSPANP00000043438 ENSPANP00000043438 AGR2 AGR2 MYOCD MYOCD ZIC3 ZIC3 ENSPANP00000047678 ENSPANP00000047678
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
YIPF6Protein YIPF. (219 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSPANP00000000847Uncharacterized protein. (439 aa)
DNAAF1Dynein assembly factor 1, axonemal. (713 aa)
BCL2BCL2 apoptosis regulator. (238 aa)
PRDM1PR/SET domain 1. (825 aa)
PDX1Pancreatic and duodenal homeobox 1. (281 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
NKX2-6NK2 homeobox 6. (301 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
NIPBLNipped-B protein. (2776 aa)
CCDC39Coiled-coil domain containing 39. (922 aa)
GLI1GLI family zinc finger 1. (1106 aa)
SOX17SRY-box transcription factor 17. (412 aa)
GATA6GATA binding protein 6. (595 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (478 aa)
CLMPCXADR like membrane protein. (374 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CTNNB1Catenin beta 1. (781 aa)
FOXF1Forkhead box F1. (432 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
C1GALT1Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (371 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
AHI1Abelson helper integration site 1. (1203 aa)
IFT172Intraflagellar transport 172. (1724 aa)
GATA4GATA binding protein 4. (442 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
CPS1Carbamoyl-phosphate synthase 1. (1507 aa)
BBS7Bardet-Biedl syndrome 7. (594 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
HOXA5Homeobox A5 (Predicted). (270 aa)
OTCOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
ALX4ALX homeobox 4. (409 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (507 aa)
HLXH2.0 like homeobox. (494 aa)
MIXL1Mix paired-like homeobox. (240 aa)
KLF5Kruppel like factor 5. (457 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
TYMSThymidylate synthetase. (313 aa)
DCHS1Dachsous cadherin-related 1. (3296 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
TCF21Transcription factor 21. (179 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (688 aa)
VPS52VPS52 subunit of GARP complex. (723 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (335 aa)
SALL1Spalt like transcription factor 1. (1318 aa)
SOX10SRY-box transcription factor 10. (377 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4297 aa)
RBPMS2RNA binding protein, mRNA processing factor 2. (208 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
PTK6Tyrosine-protein kinase. (451 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2589 aa)
IL6STInterleukin 6 signal transducer. (942 aa)
HOXD13Homeobox D13. (343 aa)
SCTSecretin. (125 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
EXT1Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). (746 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
NOTCH1Notch receptor 1. (2541 aa)
FOXL1Forkhead box L1. (328 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
CCDC40Coiled-coil domain containing 40. (1145 aa)
GLI2GLI family zinc finger 2. (1552 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
BMP4Bone morphogenetic protein 4, isoform 3 (Predicted). (408 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
NKX2-2NK2 homeobox 2. (273 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (456 aa)
SIX2SIX homeobox 2. (290 aa)
RB1RB transcriptional corepressor 1. (889 aa)
NKX3-2NK3 homeobox 2. (333 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
ASS1Uncharacterized protein. (412 aa)
FOXE1Forkhead box E1. (369 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1843 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
NODALNodal growth differentiation factor. (330 aa)
ENSPANP00000020409Uncharacterized protein. (375 aa)
TBX2T-box transcription factor 2. (704 aa)
PYYPeptide YY. (97 aa)
CCDC103Coiled-coil domain containing 103. (242 aa)
HOXA13Homeobox A13. (367 aa)
ENSPANP00000021415Uncharacterized protein. (442 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
STRA6Stimulated by retinoic acid 6. (707 aa)
GATA5GATA binding protein 5. (339 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (832 aa)
PERCC1Uncharacterized protein. (257 aa)
MEGF8Multiple EGF like domains 8. (2825 aa)
SRCTyrosine-protein kinase. (644 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (951 aa)
ENSPANP00000029568Uncharacterized protein. (299 aa)
ADAA_deaminase domain-containing protein. (449 aa)
CBFA2T2CBFA2/RUNX1 partner transcriptional co-repressor 2. (614 aa)
SHOX2Short stature homeobox 2. (355 aa)
EPHB3EPH receptor B3. (1008 aa)
RARBRetinoic acid receptor beta. (448 aa)
COBLCordon-bleu WH2 repeat protein. (1309 aa)
YAP1Yes associated protein 1. (506 aa)
SMAD2Mothers against decapentaplegic homolog. (472 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (686 aa)
NKX2-3NK2 homeobox 3. (365 aa)
GLI3GLI family zinc finger 3. (1580 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (221 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (540 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
CCKBRCholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (450 aa)
CDX2Caudal type homeobox 2. (313 aa)
ENSPANP00000043438Uncharacterized protein. (435 aa)
AGR2Anterior gradient 2, protein disulphide isomerase family member. (188 aa)
MYOCDMyocardin. (984 aa)
ZIC3Zic family member 3. (466 aa)
ENSPANP00000047678Uncharacterized protein. (103 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
Server load: low (18%) [HD]