STRINGSTRING
MMP14 MMP14 MED12 MED12 TBX1 TBX1 NIPBL NIPBL SETD2 SETD2 CHST11 CHST11 TBX15 TBX15 NDST1 NDST1 FOXC2 FOXC2 ALX3 ALX3 GRHL2 GRHL2 TGFBR2 TGFBR2 LOC100999447 LOC100999447 HOXA2 HOXA2 RDH10 RDH10 NODAL NODAL WNT9B WNT9B FGF8 FGF8 RUNX2 RUNX2 LOC103887915 LOC103887915 FGFR2 FGFR2 TULP3 TULP3 MMP16 MMP16 SIX4 SIX4 SIX1 SIX1 SMAD2 SMAD2 GLI3 GLI3 IFT140 IFT140 PRRX1 PRRX1 WDR19 WDR19 ENSPANP00000046447 ENSPANP00000046447 ENSPANP00000046911 ENSPANP00000046911 PAX5 PAX5 TGFBR1 TGFBR1 HOXA1 HOXA1 DLX2 DLX2 SIX2 SIX2 BMP4 BMP4 EIF4A3 EIF4A3 TGFB3 TGFB3 MTHFD1L MTHFD1L SMAD3 SMAD3 TFAP2A TFAP2A IRX5 IRX5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MMP14Matrix metallopeptidase 14. (582 aa)
MED12Mediator complex subunit 12. (2178 aa)
TBX1T-box transcription factor 1. (491 aa)
NIPBLNipped-B protein. (2776 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2544 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
TBX15T-box transcription factor 15. (602 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (883 aa)
FOXC2Forkhead box C2. (494 aa)
ALX3ALX homeobox 3. (343 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LOC100999447Uncharacterized protein. (324 aa)
HOXA2Homeobox protein Hox-A2; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. Proboscipedia subfamily. (377 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
NODALNodal growth differentiation factor. (330 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
RUNX2RUNX family transcription factor 2. (611 aa)
LOC103887915Uncharacterized protein. (245 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
TULP3TUB like protein 3; Belongs to the TUB family. (490 aa)
MMP16Matrix metallopeptidase 16. (607 aa)
SIX4SIX homeobox 4. (780 aa)
SIX1SIX homeobox 1. (284 aa)
SMAD2Mothers against decapentaplegic homolog. (472 aa)
GLI3GLI family zinc finger 3. (1580 aa)
IFT140Intraflagellar transport 140. (1475 aa)
PRRX1Paired related homeobox 1. (217 aa)
WDR19WD repeat domain 19. (1348 aa)
ENSPANP00000046447Uncharacterized protein. (115 aa)
ENSPANP00000046911Uncharacterized protein; Belongs to the DEAD box helicase family. (385 aa)
PAX5Paired box 5. (364 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
HOXA1Homeobox A1, isoform 1 (Predicted). (335 aa)
DLX2Distal-less homeobox 2. (328 aa)
SIX2SIX homeobox 2. (290 aa)
BMP4Bone morphogenetic protein 4, isoform 3 (Predicted). (408 aa)
EIF4A3Uncharacterized protein; Belongs to the DEAD box helicase family. (411 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (976 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
IRX5Iroquois homeobox 5. (483 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
Server load: low (12%) [HD]