STRINGSTRING
ALX1 ALX1 EFNB1 EFNB1 OSR1 OSR1 FOXC2 FOXC2 FLNA FLNA TGFB1 TGFB1 TBX3 TBX3 HEY1 HEY1 LOXL3 LOXL3 WNT4 WNT4 KITLG KITLG ERBB4 ERBB4 FGFR1 FGFR1 TCOF1 TCOF1 SEMA4F SEMA4F HGF HGF SFRP1 SFRP1 NOG NOG TBX1 TBX1 BCL2 BCL2 SEMA6B SEMA6B OTUD5 OTUD5 GDNF GDNF FGF10 FGF10 FOLR1 FOLR1 WWTR1 WWTR1 ENSPANP00000000049 ENSPANP00000000049 PEF1 PEF1 FAM172A FAM172A SEMA5B SEMA5B RANBP3L RANBP3L DLG5 DLG5 TMEM100 TMEM100 CYP26C1 CYP26C1 TGFBR1 TGFBR1 MEF2C MEF2C LOXL2 LOXL2 PAX2 PAX2 SEMA4G SEMA4G FGF8 FGF8 NOLC1 NOLC1 ROCK1 ROCK1 PHACTR4 PHACTR4 PPP3R1 PPP3R1 ENSPANP00000022948 ENSPANP00000022948 ACVR1 ACVR1 FGFR2 FGFR2 ENSPANP00000024775 ENSPANP00000024775 OLFM1 OLFM1 MAPK1 MAPK1 STAT1 STAT1 GSK3B GSK3B ISL1 ISL1 HIF1A HIF1A ANXA6 ANXA6 ADAM15 ADAM15 RET RET NRP1 NRP1 RFLNB RFLNB SEMA4D SEMA4D AKNA AKNA TGFBR3L TGFBR3L FRZB FRZB TAPT1 TAPT1 MSX1 MSX1 CORO1C CORO1C SEMA3B SEMA3B FAM83D FAM83D FGF19 FGF19 SIX2 SIX2 RADIL RADIL SHH SHH OVOL2 OVOL2 JAG1 JAG1 BMP4 BMP4 SMO SMO DDX5 DDX5 SEMA5A SEMA5A NRG1 NRG1 PITX2 PITX2 LEF1 LEF1 ENG ENG TRIM28 TRIM28 TASOR TASOR FN1 FN1 SEMA3E SEMA3E BMP2 BMP2 HMGA2 HMGA2 ALDH1A2 ALDH1A2 ENSPANP00000041518 ENSPANP00000041518 BMPR1A BMPR1A HEY2 HEY2 SOX9 SOX9 WNT10A WNT10A NOTCH1 NOTCH1 HTR2B HTR2B EXT1 EXT1 DACT3 DACT3 PHOX2B PHOX2B POLR1B POLR1B SNAI1 SNAI1 ZFP64 ZFP64 BMP7 BMP7 EDN3 EDN3 LAMA5 LAMA5 SEMA4B SEMA4B SEMA7A SEMA7A EDN1 EDN1 SOX8 SOX8 FOXC1 FOXC1 DDX17 DDX17 SOX10 SOX10 GSC GSC ROCK2 ROCK2 RPS7 RPS7 CUL7 CUL7 MAPK3 MAPK3 NOTCH4 NOTCH4 SEMA4C SEMA4C TGFBR3 TGFBR3 FBXL17 FBXL17 SPRY1 SPRY1 EPB41L5 EPB41L5 RDH10 RDH10 S100A4 S100A4 SEMA6A SEMA6A KLHL12 KLHL12 EOMES EOMES TCF21 TCF21 KBTBD8 KBTBD8 AMER1 AMER1 EFNA1 EFNA1 NRTN NRTN GBX2 GBX2 HNRNPAB HNRNPAB WNT16 WNT16 CDH2 CDH2 EDNRB EDNRB NRP2 NRP2 LRP6 LRP6 LOC101003703 LOC101003703 HAS2 HAS2 WNT8A WNT8A SEMA4A SEMA4A WNT11 WNT11 WNT2 WNT2 SMAD4 SMAD4 TBX20 TBX20 SEMA6C SEMA6C HEYL HEYL EDNRA EDNRA RTN4 RTN4 SEMA3A SEMA3A SNAI2 SNAI2 SEMA3D SEMA3D SEMA3C SEMA3C WNT5A WNT5A SEMA3G SEMA3G CTNNB1 CTNNB1 TGFB2 TGFB2 SEMA3F SEMA3F
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALX1ALX homeobox 1. (326 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
FOXC2Forkhead box C2. (494 aa)
FLNAUncharacterized protein. (2647 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TBX3T-box transcription factor 3. (743 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
LOXL3Lysyl oxidase like 3. (753 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
ERBB4Receptor protein-tyrosine kinase. (1224 aa)
FGFR1Fibroblast growth factor receptor. (853 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1524 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TBX1T-box transcription factor 1. (491 aa)
BCL2BCL2 apoptosis regulator. (238 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (841 aa)
OTUD5OTU deubiquitinase 5. (587 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FOLR1Folate receptor alpha. (257 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
ENSPANP0000000004940S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (202 aa)
PEF1Penta-EF-hand domain containing 1. (283 aa)
FAM172AFamily with sequence similarity 172 member A. (416 aa)
SEMA5BSemaphorin 5B. (1125 aa)
RANBP3LRAN binding protein 3 like. (490 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1920 aa)
TMEM100Transmembrane protein 100. (134 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
LOXL2Lysyl oxidase like 2. (774 aa)
PAX2Paired box 2. (436 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (844 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (771 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
PHACTR4Phosphatase and actin regulator. (656 aa)
PPP3R1Uncharacterized protein. (189 aa)
ENSPANP0000002294840S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (173 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
ENSPANP00000024775Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (468 aa)
OLFM1Olfactomedin 1. (485 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
STAT1Signal transducer and activator of transcription. (791 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
ISL1ISL LIM homeobox 1. (395 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (832 aa)
ANXA6Annexin. (685 aa)
ADAM15ADAM metallopeptidase domain 15. (863 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
RFLNBRefilin B. (144 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
AKNAAT-hook transcription factor. (1438 aa)
TGFBR3LTransforming growth factor beta receptor 3 like. (310 aa)
FRZBFrizzled related protein. (325 aa)
TAPT1Transmembrane anterior posterior transformation 1. (567 aa)
MSX1Msh homeobox 1. (284 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (530 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (783 aa)
FAM83DFamily with sequence similarity 83 member D. (645 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
SIX2SIX homeobox 2. (290 aa)
RADILRap associating with DIL domain. (1071 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (456 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1190 aa)
BMP4Bone morphogenetic protein 4, isoform 3 (Predicted). (408 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
SEMA5ASemaphorin 5A. (1074 aa)
NRG1Neuregulin 1. (713 aa)
PITX2Homeobox protein. (325 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
ENGZP domain-containing protein. (274 aa)
TRIM28Tripartite motif containing 28. (818 aa)
TASORTranscription activation suppressor. (1612 aa)
FN1Fibronectin 1. (2477 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (540 aa)
ENSPANP0000004151840S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (179 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (326 aa)
SOX9SRY-box transcription factor 9. (509 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
NOTCH1Notch receptor 1. (2541 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
EXT1Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). (746 aa)
DACT3Dishevelled binding antagonist of beta catenin 3. (631 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1164 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
ZFP64ZFP64 zinc finger protein. (681 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
EDN3Endothelin 3. (230 aa)
LAMA5Laminin subunit alpha 5. (3694 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (831 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (668 aa)
EDN1Endothelin 1. (211 aa)
SOX8SRY-box transcription factor 8. (446 aa)
FOXC1Fork-head domain-containing protein. (210 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (733 aa)
SOX10SRY-box transcription factor 10. (377 aa)
GSCGoosecoid homeobox. (259 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
RPS7Ribosomal protein S7. (194 aa)
CUL7Cullin 7; Belongs to the cullin family. (1656 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
NOTCH4Notch receptor 4. (2000 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
FBXL17F-box and leucine rich repeat protein 17. (703 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (688 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
S100A4Protein S100; Belongs to the S-100 family. (101 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
KLHL12BTB domain-containing protein. (568 aa)
EOMESEomesodermin. (705 aa)
TCF21Transcription factor 21. (179 aa)
KBTBD8Kelch repeat and BTB domain containing 8. (601 aa)
AMER1APC membrane recruitment protein 1. (990 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
NRTNNeurturin. (197 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B. (332 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (507 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (925 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
LOC10100370340S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
HAS2Hyaluronan synthase 2. (552 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (760 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TBX20T-box transcription factor 20. (447 aa)
SEMA6CSema domain-containing protein; Belongs to the semaphorin family. (962 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
RTN4Reticulon. (1194 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (777 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (782 aa)
CTNNB1Catenin beta 1. (781 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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