STRINGSTRING
BMP4 BMP4 RASSF2 RASSF2 SOS1 SOS1 POLB POLB JAK2 JAK2 JAM3 JAM3 ADGRF5 ADGRF5 KRAS KRAS ENSPANP00000046779 ENSPANP00000046779 FOXA3 FOXA3 IREB2 IREB2 MEF2C MEF2C LOC100998899 LOC100998899 FSTL1 FSTL1 LOC110742924 LOC110742924 BTK BTK SLC11A2 SLC11A2 ENSPANP00000045065 ENSPANP00000045065 BAP1 BAP1 ARID4A ARID4A NCSTN NCSTN DOCK11 DOCK11 STAT5B STAT5B DOCK10 DOCK10 ENSPANP00000041355 ENSPANP00000041355 UBA5 UBA5 DMTN DMTN TNFSF14 TNFSF14 FOXP3 FOXP3 CXCL2 CXCL2 BAK1 BAK1 KLF1 KLF1 TRIM10 TRIM10 JMJD6 JMJD6 NKX2-3 NKX2-3 ERCC2 ERCC2 LGALS2 LGALS2 GIGYF2 GIGYF2 PTBP3 PTBP3 ENSPANP00000036984 ENSPANP00000036984 MTHFD1 MTHFD1 LRRC19 LRRC19 BAX BAX MAEA MAEA CORO1A CORO1A L3MBTL3 L3MBTL3 ENSPANP00000035568 ENSPANP00000035568 EPAS1 EPAS1 NLRP6 NLRP6 CCN3 CCN3 ABL1 ABL1 SLC37A4 SLC37A4 ENSPANP00000033846 ENSPANP00000033846 PDE4B PDE4B FLT3 FLT3 ENSPANP00000032578 ENSPANP00000032578 WDR48 WDR48 G6PD G6PD SLC25A38 SLC25A38 PRDX5 PRDX5 ADA ADA ENSPANP00000029568 ENSPANP00000029568 LGR4 LGR4 ENSPANP00000029430 ENSPANP00000029430 UBAP2L UBAP2L THRA THRA ENSPANP00000028630 ENSPANP00000028630 CCR7 CCR7 HIF1A HIF1A ENSPANP00000026850 ENSPANP00000026850 CARD11 CARD11 ENSPANP00000026331 ENSPANP00000026331 ENSPANP00000026174 ENSPANP00000026174 CX3CR1 CX3CR1 NBEA NBEA ENSPANP00000025405 ENSPANP00000025405 TSPO2 TSPO2 PKN1 PKN1 STAMBPL1 STAMBPL1 GPAM GPAM IL6 IL6 PPP3CB PPP3CB ENSPANP00000022457 ENSPANP00000022457 SEPTIN4-2 SEPTIN4-2 VPS54 VPS54 ASXL1 ASXL1 CXCL1 CXCL1 SLC4A1 SLC4A1 KLHL10 KLHL10 LIPA LIPA MED1 MED1 SEPTIN4 SEPTIN4 HOXB6 HOXB6 CDK5RAP3 CDK5RAP3 NLE1 NLE1 NF1 NF1 GATA3 GATA3 FOXN1 FOXN1 TNFRSF13B TNFRSF13B SPNS2 SPNS2 FANCC FANCC ANXA1 ANXA1 LOC101000688 LOC101000688 SIT1 SIT1 SLC46A2 SLC46A2 RC3H2 RC3H2 KIT KIT SLC25A40 SLC25A40 LYAR LYAR GCNT4 GCNT4 GPR174 GPR174 CAMLG CAMLG SMAD5 SMAD5 CEBPG CEBPG AP3B1 AP3B1 BCL2 BCL2 NCAPG2 NCAPG2 AKT3 AKT3 LPCAT3 LPCAT3 TAL1 TAL1 ZFPM1 ZFPM1 CSF1 CSF1 RB1 RB1 BCL2L11 BCL2L11 SLC40A1 SLC40A1 ENSPANP00000017998 ENSPANP00000017998 ABCB10 ABCB10 NOS3 NOS3 HCLS1 HCLS1 RIPK3 RIPK3 IKZF1 IKZF1 TRAF3IP2 TRAF3IP2 MPIG6B MPIG6B PLA2G2A PLA2G2A KITLG KITLG SPTA1 SPTA1 HAMP HAMP HSPA9 HSPA9 OCIAD2 OCIAD2 GPR183 GPR183 EPO EPO F2R F2R ARHGEF5 ARHGEF5 TGFB1 TGFB1 LYN LYN TNFSF13B TNFSF13B RC3H1 RC3H1 IL20RB IL20RB MPL MPL XKR8 XKR8 EZH2 EZH2 ITPKB ITPKB AXL AXL JAK3 JAK3 SH2B3 SH2B3 ATP5IF1 ATP5IF1 MYCT1 MYCT1 EMX1 EMX1 PTPN11 PTPN11 DYRK3 DYRK3 IL7 IL7 GATA1 GATA1 ADAR ADAR RPS14 RPS14 PRDM14 PRDM14 GATA2 GATA2 RAG1 RAG1 SFXN1 SFXN1 SART3 SART3 IL7R IL7R SASH3 SASH3 CXCL6 CXCL6 ACIN1 ACIN1 PTPN2 PTPN2 NAPEPLD NAPEPLD FH FH MERTK MERTK TCIRG1 TCIRG1 ARMCX1 ARMCX1 KLF2 KLF2 INHA INHA LOC100997022 LOC100997022 ZNF251 ZNF251 ZC3H8 ZC3H8 ETV2 ETV2 FADD FADD RHEX RHEX P2RX7 P2RX7 DNASE2 DNASE2 GPRASP2 GPRASP2 KCNQ1 KCNQ1 MYB MYB UFL1 UFL1 CRISPLD1 CRISPLD1 SP3 SP3 SLC15A4 SLC15A4 NCKAP1L NCKAP1L TGFBR3 TGFBR3 KMT2E KMT2E SCNN1B SCNN1B LAT LAT AHSP AHSP SRF SRF PKNOX1 PKNOX1 RHAG RHAG HMOX1 HMOX1 RCOR1 RCOR1 SIVA1 SIVA1 AKT1 AKT1 BRD1 BRD1 SOX4 SOX4 GLIS2 GLIS2 DNAJA3 DNAJA3 TNFRSF17 TNFRSF17 PLA2G10 PLA2G10 TMOD3 TMOD3 CCNB2 CCNB2 FAM210B FAM210B BCL6 BCL6 FLVCR1 FLVCR1 PRDX1 PRDX1 ZBTB7A ZBTB7A ILDR2 ILDR2 LOC101016948 LOC101016948 SKIL SKIL TNFAIP3 TNFAIP3 EMCN EMCN SOD1 SOD1 EXT1 EXT1 HIPK2 HIPK2 INHBA INHBA ZNHIT1 ZNHIT1 BCR BCR HSCB HSCB NOTCH1 NOTCH1 CARD9 CARD9 CCR4 CCR4 ST6GALNAC1 ST6GALNAC1 C15orf41 C15orf41 LRRC45 LRRC45 SOX9 SOX9 SMO SMO PPP2R3C PPP2R3C SOS2 SOS2 MFHAS1 MFHAS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP4Bone morphogenetic protein 4, isoform 3 (Predicted). (408 aa)
RASSF2Ras association domain family member 2. (326 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (370 aa)
JAK2Tyrosine-protein kinase. (1133 aa)
JAM3Junctional adhesion molecule 3. (329 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1383 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ENSPANP00000046779DUF1279 domain-containing protein. (164 aa)
FOXA3Forkhead box A3. (350 aa)
IREB2Iron responsive element binding protein 2. (1070 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
LOC100998899Uncharacterized protein. (72 aa)
FSTL1Follistatin like 1. (308 aa)
LOC110742924AIG1-type G domain-containing protein. (307 aa)
BTKTyrosine-protein kinase. (659 aa)
SLC11A2Solute carrier family 11 member 2. (590 aa)
ENSPANP000000450651-cysPrx_C domain-containing protein. (94 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (736 aa)
ARID4AAT-rich interaction domain 4A. (1262 aa)
NCSTNNicastrin. (721 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (2086 aa)
STAT5BSignal transducer and activator of transcription. (791 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2156 aa)
ENSPANP00000041355Uncharacterized protein. (489 aa)
UBA5Ubiquitin like modifier activating enzyme 5. (417 aa)
DMTNDematin actin binding protein. (406 aa)
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa)
FOXP3Forkhead box P3. (456 aa)
CXCL2C-X-C motif chemokine. (107 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
KLF1Kruppel like factor 1. (362 aa)
TRIM10Tripartite motif containing 10. (481 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (420 aa)
NKX2-3NK2 homeobox 3. (365 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
LGALS2Galectin. (139 aa)
GIGYF2GRB10 interacting GYF protein 2. (1325 aa)
PTBP3Polypyrimidine tract binding protein 3. (558 aa)
ENSPANP00000036984Uncharacterized protein. (107 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (991 aa)
LRRC19Leucine rich repeat containing 19. (370 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
MAEAMacrophage erythroblast attacher. (421 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (487 aa)
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (780 aa)
ENSPANP0000003556840S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (227 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
NLRP6NLR family pyrin domain containing 6. (1045 aa)
CCN3Cellular communication network factor 3. (366 aa)
ABL1Tyrosine-protein kinase. (1112 aa)
SLC37A4Solute carrier family 37 member 4. (451 aa)
ENSPANP00000033846Uncharacterized protein. (542 aa)
PDE4BPhosphodiesterase. (736 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (995 aa)
ENSPANP00000032578Uncharacterized protein; Belongs to the universal ribosomal protein uS11 family. (129 aa)
WDR48WD repeat domain 48. (679 aa)
G6PDUncharacterized protein. (561 aa)
SLC25A38Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (321 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (215 aa)
ADAA_deaminase domain-containing protein. (449 aa)
ENSPANP00000029568Uncharacterized protein. (299 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (951 aa)
ENSPANP00000029430Uncharacterized protein. (164 aa)
UBAP2LUbiquitin associated protein 2 like. (1165 aa)
THRAThyroid hormone receptor alpha. (602 aa)
ENSPANP00000028630Uncharacterized protein. (441 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (832 aa)
ENSPANP0000002685040S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (203 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
ENSPANP00000026331Uncharacterized protein; Belongs to the heat shock protein 70 family. (556 aa)
ENSPANP00000026174Uncharacterized protein. (165 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (384 aa)
NBEANeurobeachin. (2768 aa)
ENSPANP00000025405Uncharacterized protein. (909 aa)
TSPO2Translocator protein 2. (170 aa)
PKN1Protein kinase N1. (955 aa)
STAMBPL1STAM binding protein like 1. (461 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
IL6Uncharacterized protein. (214 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
ENSPANP00000022457Uncharacterized protein. (208 aa)
SEPTIN4-2Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (493 aa)
VPS54VPS54 subunit of GARP complex. (966 aa)
ASXL1ASXL transcriptional regulator 1. (1545 aa)
CXCL1C-X-C motif chemokine. (107 aa)
SLC4A1Anion exchange protein. (951 aa)
KLHL10Kelch like family member 10. (608 aa)
LIPALipase; Belongs to the AB hydrolase superfamily. Lipase family. (401 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1548 aa)
SEPTIN4Septin 4. (570 aa)
HOXB6Homeobox B6. (224 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (541 aa)
NLE1Notchless homolog 1. (485 aa)
NF1Neurofibromin 1. (2839 aa)
GATA3GATA binding protein 3. (444 aa)
FOXN1Forkhead box N1. (648 aa)
TNFRSF13BTNF receptor superfamily member 13B. (269 aa)
SPNS2Sphingolipid transporter 2. (549 aa)
FANCCFanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (558 aa)
ANXA1Annexin. (346 aa)
LOC10100068840S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
SIT1Signaling threshold regulating transmembrane adaptor 1. (224 aa)
SLC46A2Solute carrier family 46 member 2. (475 aa)
RC3H2Ring finger and CCCH-type domains 2. (1177 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
SLC25A40Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family. (338 aa)
LYARLy1 antibody reactive. (340 aa)
GCNT4Glucosaminyl (N-acetyl) transferase 4. (453 aa)
GPR174G protein-coupled receptor 174. (333 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (296 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1088 aa)
BCL2BCL2 apoptosis regulator. (238 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1145 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa)
ZFPM1Zinc finger protein, FOG family member 1. (1002 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (555 aa)
RB1RB transcriptional corepressor 1. (889 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (573 aa)
ENSPANP00000017998Uncharacterized protein; Belongs to the heat shock protein 70 family. (555 aa)
ABCB10ATP binding cassette subfamily B member 10. (738 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (476 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (518 aa)
IKZF1IKAROS family zinc finger 1. (519 aa)
TRAF3IP2TRAF3 interacting protein 2. (570 aa)
MPIG6BMegakaryocyte and platelet inhibitory receptor G6b. (241 aa)
PLA2G2APhospholipase A(2). (144 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2420 aa)
HAMPHepcidin antimicrobial peptide. (84 aa)
HSPA9Uncharacterized protein; Belongs to the heat shock protein 70 family. (679 aa)
OCIAD2OCIA domain containing 2. (154 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1597 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
LYNTyrosine-protein kinase. (512 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa)
RC3H1Ring finger and CCCH-type domains 1. (1133 aa)
IL20RBInterleukin 20 receptor subunit beta. (175 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (646 aa)
XKR8XK-related protein. (401 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (947 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
JAK3Tyrosine-protein kinase. (1147 aa)
SH2B3SH2B adaptor protein 3. (570 aa)
ATP5IF1Uncharacterized protein. (106 aa)
MYCT1MYC target 1. (235 aa)
EMX1Empty spiracles homeobox 1. (290 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (588 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (177 aa)
GATA1GATA binding protein 1. (413 aa)
ADARAdenosine deaminase RNA specific. (1364 aa)
RPS14Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (166 aa)
PRDM14PR/SET domain 14. (571 aa)
GATA2GATA binding protein 2. (480 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
SFXN1Sidoreflexin. (322 aa)
SART3Spliceosome associated factor 3, U4/U6 recycling protein. (981 aa)
IL7RInterleukin 7 receptor. (459 aa)
SASH3SAM and SH3 domain containing 3. (379 aa)
CXCL6C-X-C motif chemokine. (114 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1339 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (415 aa)
NAPEPLDN-acyl phosphatidylethanolamine phospholipase D. (393 aa)
FHFumarate hydratase. (542 aa)
MERTKMER proto-oncogene, tyrosine kinase. (1027 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
ARMCX1Armadillo repeat containing X-linked 1. (453 aa)
KLF2Kruppel like factor 2. (356 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa)
LOC10099702240S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
ZNF251Zinc finger protein 251. (671 aa)
ZC3H8Zinc finger CCCH-type containing 8. (295 aa)
ETV2ETS variant 2. (370 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
RHEXRegulator of hemoglobinization and erythroid cell expansion. (178 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (537 aa)
DNASE2Deoxyribonuclease 2, lysosomal. (360 aa)
GPRASP2G protein-coupled receptor associated sorting protein 2. (838 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
UFL1UFM1 specific ligase 1. (793 aa)
CRISPLD1Cysteine rich secretory protein LCCL domain containing 1. (500 aa)
SP3Sp3 transcription factor. (780 aa)
SLC15A4Solute carrier family 15 member 4. (496 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
KMT2ELysine methyltransferase 2E. (1858 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (640 aa)
LATLinker for activation of T cells. (270 aa)
AHSPAlpha hemoglobin stabilizing protein. (102 aa)
SRFSerum response factor. (508 aa)
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)
RHAGRh associated glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (460 aa)
HMOX1Heme oxygenase 1. (288 aa)
RCOR1REST corepressor 1. (486 aa)
SIVA1Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
BRD1Bromodomain containing 1. (1058 aa)
SOX4Transcription factor SOX. (448 aa)
GLIS2GLIS family zinc finger 2. (483 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
TNFRSF17TNF receptor superfamily member 17. (183 aa)
PLA2G10Phospholipase A(2). (165 aa)
TMOD3Tropomodulin 3. (352 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (398 aa)
FAM210BFamily with sequence similarity 210 member B. (192 aa)
BCL6BCL6 transcription repressor. (700 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (555 aa)
PRDX1Peroxiredoxin 1. (199 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (584 aa)
ILDR2Immunoglobulin like domain containing receptor 2. (639 aa)
LOC101016948ATPase inhibitor, mitochondrial. (106 aa)
SKILSKI like proto-oncogene. (684 aa)
TNFAIP3TNF alpha induced protein 3. (804 aa)
EMCNEndomucin. (266 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
EXT1Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). (746 aa)
HIPK2Homeodomain interacting protein kinase 2. (1158 aa)
INHBAInhibin subunit beta A. (426 aa)
ZNHIT1Zinc finger HIT-type containing 1. (154 aa)
BCRBCR activator of RhoGEF and GTPase. (1083 aa)
HSCBHscB mitochondrial iron-sulfur cluster cochaperone. (235 aa)
NOTCH1Notch receptor 1. (2541 aa)
CARD9Caspase recruitment domain family member 9. (535 aa)
CCR4C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (360 aa)
ST6GALNAC1ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (511 aa)
C15orf41Chromosome 15 open reading frame 41. (281 aa)
LRRC45Leucine rich repeat containing 45. (675 aa)
SOX9SRY-box transcription factor 9. (509 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
PPP2R3CProtein phosphatase 2 regulatory subunit B''gamma. (453 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1074 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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