STRINGSTRING
SLC9A1 SLC9A1 DSC2 DSC2 SCN10A SCN10A ZC3H12A ZC3H12A DMD DMD CASQ2 CASQ2 BIN1 BIN1 SMAD7 SMAD7 RGS2 RGS2 ANK2 ANK2 SCN5A SCN5A NOS1 NOS1 GATA4 GATA4 STC1 STC1 ADRA1B ADRA1B ACE2 ACE2 RNF207 RNF207 ANKRD44 ANKRD44 BMP10 BMP10 NKX2-5 NKX2-5 TNNI3 TNNI3 NPPA NPPA KCNQ1 KCNQ1 CALM3 CALM3 PIK3CG PIK3CG ASB3 ASB3 ANKRD66 ANKRD66 DSP DSP CALM1 CALM1 CAV1 CAV1 GJA5 GJA5 DSG2 DSG2 PDE5A PDE5A CCN2 CCN2 TMEM38B TMEM38B RANGRF RANGRF CTNNA3 CTNNA3 CLIC2 CLIC2 JUP JUP GSTO1 GSTO1 TMEM38A TMEM38A ENSPANP00000022319 ENSPANP00000022319 HRC HRC CACNA1C CACNA1C ENSPANP00000025300 ENSPANP00000025300 ENSPANP00000026012 ENSPANP00000026012 ENSPANP00000026710 ENSPANP00000026710 CALM2 CALM2 ENSPANP00000030371 ENSPANP00000030371 CAV3 CAV3 ADRA1A ADRA1A ASPH ASPH P2RX4 P2RX4 PDE4D PDE4D RYR2 RYR2 ENSPANP00000033457 ENSPANP00000033457 PDE4B PDE4B PKP2 PKP2 ANKRD28 ANKRD28 DLG1 DLG1 ENSPANP00000039289 ENSPANP00000039289 FKBP1B FKBP1B SUMO1 SUMO1 SLC8A1 SLC8A1 AKAP9 AKAP9 ENSPANP00000044796 ENSPANP00000044796 LOC101000074 LOC101000074 SRI SRI CAMK2D CAMK2D EHD3 EHD3 CHGA CHGA ATP2A1 ATP2A1 ATP2A2 ATP2A2 PLN PLN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
DSC2Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (901 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1959 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (601 aa)
DMDDystrophin. (3674 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (400 aa)
BIN1Bridging integrator 1. (608 aa)
SMAD7Mothers against decapentaplegic homolog. (493 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
ANK2Ankyrin 2. (3938 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
GATA4GATA binding protein 4. (442 aa)
STC1Stanniocalcin 1. (247 aa)
ADRA1BAdrenoceptor alpha 1B. (518 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
RNF207Ring finger protein 207. (634 aa)
ANKRD44Ankyrin repeat domain 44. (994 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
NKX2-5NK2 homeobox 5. (324 aa)
TNNI3Troponin I3, cardiac type. (211 aa)
NPPANatriuretic peptide A. (153 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
ASB3Ankyrin repeat and SOCS box containing 3. (557 aa)
ANKRD66Ankyrin repeat domain 66. (250 aa)
DSPDesmoplakin. (2871 aa)
CALM1Calmodulin 1. (149 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
DSG2Desmoglein 2. (1118 aa)
PDE5APhosphodiesterase. (875 aa)
CCN2Connective tissue growth factor (Predicted). (349 aa)
TMEM38BTransmembrane protein 38B. (291 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
CTNNA3Catenin alpha 3. (895 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
JUPJunction plakoglobin. (745 aa)
GSTO1Glutathione S-transferase omega 1; Belongs to the GST superfamily. (245 aa)
TMEM38ATransmembrane protein 38A. (257 aa)
ENSPANP00000022319Uncharacterized protein. (90 aa)
HRCHistidine rich calcium binding protein. (599 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
ENSPANP00000025300Uncharacterized protein. (77 aa)
ENSPANP00000026012Uncharacterized protein. (98 aa)
ENSPANP00000026710Rad60-SLD domain-containing protein. (83 aa)
CALM2Calmodulin 2. (149 aa)
ENSPANP00000030371Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
ASPHAspartate beta-hydroxylase. (762 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (404 aa)
PDE4DPhosphodiesterase. (510 aa)
RYR2Ryanodine receptor 2. (4951 aa)
ENSPANP00000033457Uncharacterized protein; Belongs to the calmodulin family. (99 aa)
PDE4BPhosphodiesterase. (736 aa)
PKP2Plakophilin 2. (879 aa)
ANKRD28Ankyrin repeat domain 28. (1059 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (938 aa)
ENSPANP00000039289Uncharacterized protein. (78 aa)
FKBP1BPeptidylprolyl isomerase. (95 aa)
SUMO1Ubiquitin-like domain-containing protein. (146 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
AKAP9A-kinase anchoring protein 9. (3922 aa)
ENSPANP00000044796Small ubiquitin-related modifier. (87 aa)
LOC101000074Uncharacterized protein. (835 aa)
SRISorcin. (198 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
EHD3EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (549 aa)
CHGAChromogranin A. (434 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1027 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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