STRINGSTRING
KCNE4 KCNE4 ANK2 ANK2 SCN5A SCN5A ZMPSTE24 ZMPSTE24 RNF207 RNF207 KCNE3 KCNE3 NOS1AP NOS1AP KCNQ1 KCNQ1 KCNH2 KCNH2 SCN4B SCN4B SNTA1 SNTA1 GJA5 GJA5 KCNH6 KCNH6 CACNA2D1 CACNA2D1 SCN1B SCN1B CAV3 CAV3 WDR1 WDR1 AKAP9 AKAP9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (220 aa)
ANK2Ankyrin 2. (3938 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (434 aa)
RNF207Ring finger protein 207. (634 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (103 aa)
NOS1APPID domain-containing protein. (690 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1159 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (243 aa)
SNTA1Syntrophin alpha 1. (505 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (994 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (247 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
WDR1WD repeat domain 1. (627 aa)
AKAP9A-kinase anchoring protein 9. (3922 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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