STRINGSTRING
JUNB JUNB NSDHL NSDHL HEY1 HEY1 FBXW8 FBXW8 WNT2 WNT2 FZD5 FZD5 TMED2 TMED2 CCN1 CCN1 AKT1 AKT1 VASH2 VASH2 HS6ST1 HS6ST1 OVOL2 OVOL2 GGNBP2 GGNBP2 PLCD3 PLCD3 ENSPANP00000024557 ENSPANP00000024557 MAPK1 MAPK1 VASH1 VASH1 HEY2 HEY2 ENSPANP00000046945 ENSPANP00000046945
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
NSDHLNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (373 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
FBXW8F-box and WD repeat domain containing 8. (597 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
CCN1Cellular communication network factor 1. (381 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
VASH2Vasohibin 2. (355 aa)
HS6ST1Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (411 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
GGNBP2Gametogenetin binding protein 2. (697 aa)
PLCD3Phosphoinositide phospholipase C. (785 aa)
ENSPANP00000024557GOLD domain-containing protein. (188 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
VASH1Vasohibin 1. (395 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (326 aa)
ENSPANP00000046945Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (294 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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