STRINGSTRING
GSKIP GSKIP WWTR1 WWTR1 FOLR1 FOLR1 FGF10 FGF10 KPNA1 KPNA1 OTUD5 OTUD5 FUZ FUZ MDK MDK NPHP4 NPHP4 UBAC2 UBAC2 RNF220 RNF220 NOG NOG JRK JRK SFRP1 SFRP1 DKK3 DKK3 RUVBL1 RUVBL1 SFRP2 SFRP2 GLI1 GLI1 ENSPANP00000003030 ENSPANP00000003030 CCAR2 CCAR2 DRAXIN DRAXIN PRKN PRKN NKD2 NKD2 NRARP NRARP HDAC1 HDAC1 TGFB1 TGFB1 DLX5 DLX5 ATP6AP2 ATP6AP2 RSPO1 RSPO1 SIAH2 SIAH2 SOX13 SOX13 EMD EMD SOX17 SOX17 EGFR EGFR LGR5 LGR5 FZD4 FZD4 FGFR2 FGFR2 ENSPANP00000022905 ENSPANP00000022905 SFRP4 SFRP4 WNK1 WNK1 DAAM2 DAAM2 ZEB2 ZEB2 EGR1 EGR1 ENSPANP00000021879 ENSPANP00000021879 RPS12 RPS12 LZTS2 LZTS2 SFRP5 SFRP5 SOST SOST FRAT1 FRAT1 JUP JUP HHEX HHEX TNKS2 TNKS2 IGFBP4 IGFBP4 BICC1 BICC1 COL1A1 COL1A1 CCNY CCNY BAMBI BAMBI NLE1 NLE1 IFT20 IFT20 SHISA6 SHISA6 TMEM88 TMEM88 CTDNEP1 CTDNEP1 WNK2 WNK2 TLE1 TLE1 GNAQ GNAQ MLLT3 MLLT3 VCP VCP RECK RECK INVS INVS FZD6 FZD6 EDA EDA ENSPANP00000046574 ENSPANP00000046574 USP34 USP34 TLE5 TLE5 ENSPANP00000046764 ENSPANP00000046764 RBX1 RBX1 CSNK1A1 CSNK1A1 RBMS3 RBMS3 LYPD6B LYPD6B TLE3 TLE3 TMEM170B TMEM170B FAM53B FAM53B MAPK14 MAPK14 SDHAF2 SDHAF2 APC2 APC2 RSPO3 RSPO3 DKK2 DKK2 CDH3 CDH3 RSPO2 RSPO2 TBX18 TBX18 DAB2 DAB2 NFKB1 NFKB1 TLE6 TLE6 PIN1 PIN1 NPPA NPPA VPS35 VPS35 LOC101005268 LOC101005268 AMER1 AMER1 TMEM198 TMEM198 PPP1CA PPP1CA DKKL1 DKKL1 OTULIN OTULIN NKX2-5 NKX2-5 FZD9 FZD9 STK11 STK11 LGR6 LGR6 EGF EGF LATS2 LATS2 TMEM9 TMEM9 FRMD8 FRMD8 FZD7 FZD7 FOXO1 FOXO1 GSK3A GSK3A PPM1N PPM1N LRRK2 LRRK2 DAPK3 DAPK3 TNN TNN OTULINL OTULINL WNT11 WNT11 SHISA3 SHISA3 PFDN5 PFDN5 LIMD1 LIMD1 IGFBP1 IGFBP1 DKK4 DKK4 AMER2 AMER2 SNAI2 SNAI2 WNT10B WNT10B PLEKHA4 PLEKHA4 TLE2 TLE2 SOX7 SOX7 WNT5A WNT5A HECW1 HECW1 GPC5 GPC5 ZNF703 ZNF703 CTNNB1 CTNNB1 CAPRIN2 CAPRIN2 SCYL2 SCYL2 JADE1 JADE1 ANKRD6 ANKRD6 USP47 USP47 TMEM64 TMEM64 CTHRC1 CTHRC1 TLE7 TLE7 GPRC5B GPRC5B GSK3B GSK3B ISL1 ISL1 KANK1 KANK1 ENSPANP00000027020 ENSPANP00000027020 CTNND2 CTNND2 GPC3 GPC3 MCC MCC LMBR1L LMBR1L DAB2IP DAB2IP LOC101006336 LOC101006336 TCF7L2 TCF7L2 SRC SRC LGR4 LGR4 ASPM ASPM RNF146 RNF146 SEMA5A SEMA5A ARNTL ARNTL ENSPANP00000031378 ENSPANP00000031378 SMURF2 SMURF2 TBL1X TBL1X PRDM15 PRDM15 PTK7 PTK7 XIAP XIAP ENSPANP00000033178 ENSPANP00000033178 ENSPANP00000033198 ENSPANP00000033198 CYLD CYLD SCEL SCEL YAP1 YAP1 SOSTDC1 SOSTDC1 GLI3 GLI3 ENSPANP00000038585 ENSPANP00000038585 CTNNBIP1 CTNNBIP1 APC APC WLS WLS BMP2 BMP2 UBR5 UBR5 ENSPANP00000039936 ENSPANP00000039936 LRP4 LRP4 ENSPANP00000040649 ENSPANP00000040649 ENSPANP00000041545 ENSPANP00000041545 CSNK1A1L CSNK1A1L CTNND1 CTNND1 ENSPANP00000041917 ENSPANP00000041917 PPM1A PPM1A DKK1 DKK1 TTC21B TTC21B MKS1 MKS1 ENSPANP00000042949 ENSPANP00000042949 APOE APOE STK3 STK3 PSEN1 PSEN1 G3BP1 G3BP1 PTPRO PTPRO ENSPANP00000045247 ENSPANP00000045247 ENSPANP00000025300 ENSPANP00000025300 DDX3X DDX3X TLE4 TLE4 FGF9 FGF9 RUVBL2 RUVBL2 BTRC BTRC CDK14 CDK14 FRZB FRZB PRICKLE1 PRICKLE1 DDIT3 DDIT3 PPM1B PPM1B MAD2L2 MAD2L2 TBL1XR1 TBL1XR1 PTPRU PTPRU ENSPANP00000017485 ENSPANP00000017485 NKD1 NKD1 AMFR AMFR SOX10 SOX10 LOC101001218 LOC101001218 CBY1 CBY1 AXIN1 AXIN1 SOX4 SOX4 USP8 USP8 SMAD3 SMAD3 GID8 GID8 MESP1 MESP1 LRRK1 LRRK1 CHD8 CHD8 WNT3A WNT3A TNKS TNKS DACT3 DACT3 TMEM131L TMEM131L ADGRA2 ADGRA2 CCDC88C CCDC88C KREMEN1 KREMEN1 NOTCH1 NOTCH1 LYPD6 LYPD6 NOTUM NOTUM AXIN2 AXIN2 SOX9 SOX9 CAV1 CAV1 DACT1 DACT1 FERMT1 FERMT1 LATS1 LATS1 SHH SHH ENSPANP00000017481 ENSPANP00000017481
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GSKIPGSK3B interacting protein. (144 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
FOLR1Folate receptor alpha. (257 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
OTUD5OTU deubiquitinase 5. (587 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
MDKMidkine. (161 aa)
NPHP4Nephrocystin 4. (1426 aa)
UBAC2UBA domain containing 2. (345 aa)
RNF220Ring finger protein 220. (566 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
JRKJrk helix-turn-helix protein. (558 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (364 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
GLI1GLI family zinc finger 1. (1106 aa)
ENSPANP00000003030PPM-type phosphatase domain-containing protein. (354 aa)
CCAR2Cell cycle and apoptosis regulator 2. (923 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (454 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (455 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
DLX5Distal-less homeobox 5. (289 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (350 aa)
RSPO1R-spondin 1. (264 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa)
SOX13SRY-box transcription factor 13. (621 aa)
EMDLEM domain-containing protein. (255 aa)
SOX17SRY-box transcription factor 17. (412 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
ENSPANP00000022905Uncharacterized protein. (152 aa)
SFRP4Secreted frizzled related protein 4. (368 aa)
WNK1WNK lysine deficient protein kinase 1. (2835 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1077 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1241 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa)
ENSPANP00000021879Uncharacterized protein. (453 aa)
RPS1240S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa)
SFRP5Secreted frizzled related protein 5. (309 aa)
SOSTSclerostin. (258 aa)
FRAT1FRAT regulator of WNT signaling pathway 1. (279 aa)
JUPJunction plakoglobin. (745 aa)
HHEXHematopoietically expressed homeobox. (270 aa)
TNKS2Poly [ADP-ribose] polymerase. (1166 aa)
IGFBP4Insulin like growth factor binding protein 4. (258 aa)
BICC1BicC family RNA binding protein 1. (946 aa)
COL1A1Collagen type I alpha 1 chain. (1369 aa)
CCNYCyclin Y; Belongs to the cyclin family. (341 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
NLE1Notchless homolog 1. (485 aa)
IFT20Intraflagellar transport 20. (158 aa)
SHISA6Shisa family member 6. (553 aa)
TMEM88Transmembrane protein 88. (159 aa)
CTDNEP1CTD nuclear envelope phosphatase 1. (244 aa)
WNK2WNK lysine deficient protein kinase 2. (2228 aa)
TLE1TLE family member 1, transcriptional corepressor. (767 aa)
GNAQG protein subunit alpha q. (384 aa)
MLLT3MLLT3 super elongation complex subunit. (570 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (808 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (971 aa)
INVSInversin. (1064 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (391 aa)
ENSPANP00000046574Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (452 aa)
USP34Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3519 aa)
TLE5TLE family member 5, transcriptional modulator. (287 aa)
ENSPANP00000046764Uncharacterized protein. (285 aa)
RBX1RING-type domain-containing protein. (108 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa)
RBMS3RNA binding motif single stranded interacting protein 3. (522 aa)
LYPD6BLY6/PLAUR domain containing 6B. (203 aa)
TLE3TLE family member 3, transcriptional corepressor. (778 aa)
TMEM170BTransmembrane protein 170B. (132 aa)
FAM53BFamily with sequence similarity 53 member B. (425 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SDHAF2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (166 aa)
APC2APC regulator of WNT signaling pathway 2. (2301 aa)
RSPO3R-spondin 3. (293 aa)
DKK2Dickkopf WNT signaling pathway inhibitor 2. (259 aa)
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (829 aa)
RSPO2R-spondin 2. (243 aa)
TBX18T-box transcription factor 18. (607 aa)
DAB2DAB adaptor protein 2. (770 aa)
NFKB1Nuclear factor kappa B subunit 1. (977 aa)
TLE6TLE family member 6, subcortical maternal complex member. (572 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
NPPANatriuretic peptide A. (153 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
LOC10100526840S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
AMER1APC membrane recruitment protein 1. (990 aa)
TMEM198Transmembrane protein 198. (360 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
DKKL1Dickkopf like acrosomal protein 1. (242 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (352 aa)
NKX2-5NK2 homeobox 5. (324 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (437 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (920 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1161 aa)
LATS2Non-specific serine/threonine protein kinase. (1086 aa)
TMEM9Transmembrane protein 9. (183 aa)
FRMD8FERM domain containing 8. (464 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
FOXO1Forkhead box O1. (655 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
PPM1NProtein phosphatase, Mg2+/Mn2+ dependent 1N (putative). (430 aa)
LRRK2Uncharacterized protein. (2479 aa)
DAPK3Death associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
TNNTenascin N. (1299 aa)
OTULINLOTU deubiquitinase with linear linkage specificity like. (358 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SHISA3Shisa family member 3. (238 aa)
PFDN5Uncharacterized protein. (160 aa)
LIMD1LIM domains containing 1. (676 aa)
IGFBP1Insulin like growth factor binding protein 1. (281 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (224 aa)
AMER2APC membrane recruitment protein 2. (665 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
PLEKHA4Pleckstrin homology domain containing A4. (772 aa)
TLE2TLE family member 2, transcriptional corepressor. (744 aa)
SOX7SRY-box transcription factor 7. (388 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1606 aa)
GPC5Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (572 aa)
ZNF703Zinc finger protein 703. (591 aa)
CTNNB1Catenin beta 1. (781 aa)
CAPRIN2Caprin family member 2. (1103 aa)
SCYL2SCY1 like pseudokinase 2. (933 aa)
JADE1Jade family PHD finger 1. (843 aa)
ANKRD6Ankyrin repeat domain 6. (727 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa)
TMEM64Transmembrane protein 64. (380 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
TLE7TLE family member 7. (441 aa)
GPRC5BG protein-coupled receptor class C group 5 member B. (421 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
ISL1ISL LIM homeobox 1. (395 aa)
KANK1KN motif and ankyrin repeat domains 1. (1352 aa)
ENSPANP00000027020Hist_deacetyl domain-containing protein. (267 aa)
CTNND2Catenin delta 2. (1135 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (603 aa)
MCCMCC regulator of WNT signaling pathway. (1014 aa)
LMBR1LLimb development membrane protein 1 like; Belongs to the LIMR family. (489 aa)
DAB2IPDAB2 interacting protein. (1183 aa)
LOC10100633640S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (150 aa)
TCF7L2Transcription factor 7 like 2. (529 aa)
SRCTyrosine-protein kinase. (644 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (951 aa)
ASPMAbnormal spindle microtubule assembly. (3468 aa)
RNF146Ring finger protein 146. (360 aa)
SEMA5ASemaphorin 5A. (1074 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (626 aa)
ENSPANP00000031378Uncharacterized protein. (433 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (682 aa)
TBL1XTransducin beta like 1 X-linked. (645 aa)
PRDM15PR/SET domain 15. (1476 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
ENSPANP00000033178C2H2-type domain-containing protein. (229 aa)
ENSPANP00000033198Hist_deacetyl domain-containing protein. (225 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
SCELSciellin. (718 aa)
YAP1Yes associated protein 1. (506 aa)
SOSTDC1Sclerostin domain containing 1. (230 aa)
GLI3GLI family zinc finger 3. (1580 aa)
ENSPANP00000038585Uncharacterized protein. (427 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
APCAPC regulator of WNT signaling pathway. (2871 aa)
WLSWnt ligand secretion mediator. (543 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2800 aa)
ENSPANP00000039936Uncharacterized protein. (85 aa)
LRP4LDL receptor related protein 4. (1906 aa)
ENSPANP0000004064940S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
ENSPANP00000041545FCP1 homology domain-containing protein. (110 aa)
CSNK1A1LCasein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (318 aa)
CTNND1Catenin delta 1. (971 aa)
ENSPANP00000041917Zf-rbx1 domain-containing protein. (93 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
TTC21BTetratricopeptide repeat domain 21B. (1315 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
ENSPANP0000004294940S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (130 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
STK3Serine/threonine kinase 3. (534 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (452 aa)
G3BP1G3BP stress granule assembly factor 1. (461 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
ENSPANP00000045247Protein kinase domain-containing protein. (214 aa)
ENSPANP00000025300Uncharacterized protein. (77 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa)
TLE4TLE family member 4, transcriptional corepressor. (797 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (473 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
CDK14Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (469 aa)
FRZBFrizzled related protein. (325 aa)
PRICKLE1Prickle planar cell polarity protein 1. (831 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (192 aa)
PPM1BProtein phosphatase, Mg2+/Mn2+ dependent 1B. (479 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (224 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (514 aa)
PTPRUProtein tyrosine phosphatase receptor type U. (1450 aa)
ENSPANP0000001748540S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (172 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (470 aa)
AMFRAutocrine motility factor receptor. (643 aa)
SOX10SRY-box transcription factor 10. (377 aa)
LOC101001218Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
CBY1Chibby family member 1, beta catenin antagonist. (169 aa)
AXIN1Axin 1, isoform 1 (Predicted). (867 aa)
SOX4Transcription factor SOX. (448 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1108 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
GID8GID complex subunit 8 homolog. (228 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (272 aa)
LRRK1Leucine rich repeat kinase 1. (2016 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2589 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
DACT3Dishevelled binding antagonist of beta catenin 3. (631 aa)
TMEM131LTransmembrane 131 like. (1610 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1341 aa)
CCDC88CCoiled-coil domain containing 88C. (2033 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (492 aa)
NOTCH1Notch receptor 1. (2541 aa)
LYPD6LY6/PLAUR domain containing 6. (154 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (509 aa)
AXIN2Axin 2. (844 aa)
SOX9SRY-box transcription factor 9. (509 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
FERMT1Fermitin family member 1. (663 aa)
LATS1Large tumor suppressor kinase 1. (1130 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (456 aa)
ENSPANP0000001748140S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (143 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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