STRINGSTRING
GZMB GZMB CASP4 CASP4 ELANE ELANE GZMA GZMA GSDME GSDME CASP8 CASP8 AIM2 AIM2 CASP1 CASP1 DPP9 DPP9 NLRP9 NLRP9 CASP6 CASP6 NAIP NAIP APIP APIP PYCARD PYCARD TREM2 TREM2 ZBP1 ZBP1 NLRC4 NLRC4 NLRP1 NLRP1 GSDMB GSDMB MEFV MEFV GSDMC GSDMC NLRP6 NLRP6 GSDMD GSDMD PYDC5 PYDC5 LOC101009375 LOC101009375
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GZMBGranzyme B; Belongs to the peptidase S1 family. (281 aa)
CASP4Caspase 4; Belongs to the peptidase C14A family. (377 aa)
ELANEPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (264 aa)
GZMAGranzyme A; Belongs to the peptidase S1 family. (262 aa)
GSDMEGasdermin E. (495 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (538 aa)
AIM2Absent in melanoma 2. (343 aa)
CASP1Caspase 1; Belongs to the peptidase C14A family. (462 aa)
DPP9Dipeptidyl peptidase 9; Belongs to the peptidase S9B family. (892 aa)
NLRP9Uncharacterized protein. (966 aa)
CASP6Caspase 6; Belongs to the peptidase C14A family. (291 aa)
NAIPNLR family apoptosis inhibitory protein. (1372 aa)
APIPMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa)
PYCARDPYD and CARD domain containing. (195 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
ZBP1Z-DNA binding protein 1. (420 aa)
NLRC4NLR family CARD domain containing 4. (1024 aa)
NLRP1NLR family pyrin domain containing 1. (1479 aa)
GSDMBGasdermin B. (394 aa)
MEFVMEFV innate immuity regulator, pyrin. (769 aa)
GSDMCGasdermin C. (507 aa)
NLRP6NLR family pyrin domain containing 6. (1045 aa)
GSDMDGasdermin D. (532 aa)
PYDC5Uncharacterized protein. (107 aa)
LOC101009375Uncharacterized protein; Belongs to the peptidase C14A family. (352 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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