STRINGSTRING
ECT2 ECT2 EZH2 EZH2 STK25 STK25 STAT6 STAT6 CAT CAT TRPA1 TRPA1 AIFM1 AIFM1 RPS3 RPS3 IL18BP IL18BP RHOB RHOB RIPK1 RIPK1 TRPM2 TRPM2 PRKCD PRKCD LOC101014578 LOC101014578 IMPACT IMPACT PDCD10 PDCD10 KLF2 KLF2 ANKZF1 ANKZF1 FABP1 FABP1 IL6 IL6 CDKN2B CDKN2B ENSPANP00000021062 ENSPANP00000021062 PAX2 PAX2 PCGF2 PCGF2 SIRT1 SIRT1 PPIF PPIF NET1 NET1 MAPK7 MAPK7 KDM6B KDM6B FXN FXN SIGMAR1 SIGMAR1 SETX SETX ARG1 ARG1 RIPK3 RIPK3 OSER1 OSER1 ZNF580 ZNF580 FYN FYN SIRPA SIRPA MAP1LC3A MAP1LC3A PLEKHA1 PLEKHA1 ERN1 ERN1 SPHK1 SPHK1 BNIP3 BNIP3 MAP3K5 MAP3K5 TNFAIP3 TNFAIP3 HDAC2 HDAC2 SMPD3 SMPD3 AQP1 AQP1 SRC SRC ENSPANP00000030512 ENSPANP00000030512 PARK7 PARK7 ENSPANP00000031797 ENSPANP00000031797 RNF112 RNF112 ABL1 ABL1 NFE2L2 NFE2L2 ENSPANP00000039389 ENSPANP00000039389 HSF1 HSF1 MAPK13 MAPK13 ENSPANP00000044280 ENSPANP00000044280 RELA RELA EDN1 EDN1 HDAC6 HDAC6 ZNF277 ZNF277 AXL AXL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ECT2Epithelial cell transforming 2. (917 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
STK25Serine/threonine kinase 25. (426 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1145 aa)
AIFM1Apoptosis inducing factor mitochondria associated 1. (613 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (259 aa)
IL18BPInterleukin 18 binding protein. (207 aa)
RHOBRas homolog family member B. (196 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (776 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1475 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
LOC101014578Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa)
IMPACTImpact RWD domain protein. (320 aa)
PDCD10Programmed cell death 10. (208 aa)
KLF2Kruppel like factor 2. (356 aa)
ANKZF1Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (727 aa)
FABP1Fatty acid binding protein 1. (127 aa)
IL6Uncharacterized protein. (214 aa)
CDKN2BUncharacterized protein. (173 aa)
ENSPANP00000021062KH type-2 domain-containing protein. (164 aa)
PAX2Paired box 2. (436 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
SIRT1Sirtuin 1. (743 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa)
NET1Neuroepithelial cell transforming 1. (587 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
KDM6BLysine demethylase 6B. (1677 aa)
FXNFrataxin. (210 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
SETXSenataxin. (2679 aa)
ARG1Arginase. (322 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (518 aa)
OSER1Oxidative stress responsive serine rich 1. (292 aa)
ZNF580Zinc finger protein 580. (172 aa)
FYNTyrosine-protein kinase. (537 aa)
SIRPAUncharacterized protein. (503 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (125 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (977 aa)
SPHK1Sphingosine kinase 1. (470 aa)
BNIP3BCL2 interacting protein 3. (259 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1483 aa)
TNFAIP3TNF alpha induced protein 3. (804 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (503 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (296 aa)
SRCTyrosine-protein kinase. (644 aa)
ENSPANP00000030512Uncharacterized protein. (55 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
ENSPANP00000031797Uncharacterized protein. (72 aa)
RNF112Ring finger protein 112. (639 aa)
ABL1Tyrosine-protein kinase. (1112 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (596 aa)
ENSPANP00000039389KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (230 aa)
HSF1Heat shock transcription factor 1. (532 aa)
MAPK13Mitogen-activated protein kinase. (386 aa)
ENSPANP00000044280Uncharacterized protein. (178 aa)
RELARELA proto-oncogene, NF-kB subunit. (476 aa)
EDN1Endothelin 1. (211 aa)
HDAC6Histone deacetylase 6. (1215 aa)
ZNF277Zinc finger protein 277. (456 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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