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NUP93 NUP93 INHBA INHBA NOTCH1 NOTCH1 ACVR1B ACVR1B TGFB3 TGFB3 ACVR2A ACVR2A UBE2O UBE2O RBPMS RBPMS GDF5 GDF5 BMP4 BMP4 FERMT1 FERMT1 ENSPANP00000018389 ENSPANP00000018389 MSX1 MSX1 CRB2 CRB2 FLCN FLCN ITGA8 ITGA8 GDF10 GDF10 NODAL NODAL FBXL15 FBXL15 SLC2A10 SLC2A10 ZEB2 ZEB2 GDF2 GDF2 ACVR1 ACVR1 FKBP8 FKBP8 SNW1 SNW1 FGF9 FGF9 ENSPANP00000024775 ENSPANP00000024775 ACVR2B ACVR2B FOXD1 FOXD1 ZNF423 ZNF423 C20orf27 C20orf27 HES5 HES5 THBS1 THBS1 NUMA1 NUMA1 TWSG1 TWSG1 INHBB INHBB ENSPANP00000033178 ENSPANP00000033178 ENSPANP00000036120 ENSPANP00000036120 BMP5 BMP5 CITED1 CITED1 ENSPANP00000036680 ENSPANP00000036680 ENG ENG SMAD2 SMAD2 KCP KCP ACVRL1 ACVRL1 BMP2 BMP2 ENSPANP00000039827 ENSPANP00000039827 ENSPANP00000040479 ENSPANP00000040479 INHBE INHBE BMPR1A BMPR1A MYOCD MYOCD TGFBR1 TGFBR1 JAK2 JAK2 HIPK2 HIPK2 GDF7 GDF7 KDR KDR BMP7 BMP7 NEO1 NEO1 RNF111 RNF111 HFE HFE CREBBP CREBBP KIAA0319 KIAA0319 BMP6 BMP6 AXIN1 AXIN1 EP300 EP300 CDH5 CDH5 ADAM17 ADAM17 HSP90AB1 HSP90AB1 TGFB1I1 TGFB1I1 SCUBE3 SCUBE3 TGFBR3 TGFBR3 BMP3 BMP3 DAB2 DAB2 GIPC3 GIPC3 MEN1 MEN1 CCN1 CCN1 INHBC INHBC STK11 STK11 GDF3 GDF3 BMP10 BMP10 INHA INHA LRG1 LRG1 GIPC2 GIPC2 CDKN1C CDKN1C GIPC1 GIPC1 LOC101011710 LOC101011710 SMAD4 SMAD4 GATA4 GATA4 TBX20 TBX20 TGFBR2 TGFBR2 BMPR2 BMPR2 BMP15 BMP15 TGFB2 TGFB2 KIAA1324L KIAA1324L NOTCH2 NOTCH2 SDCBP SDCBP TGFB1 TGFB1 GDF6 GDF6 GDF11 GDF11 GATA6 GATA6 PELO PELO PARP1 PARP1 RNF165 RNF165 ZC3H3 ZC3H3 ING2 ING2 SULF1 SULF1 ENSPANP00000001806 ENSPANP00000001806 LOC101011357 LOC101011357 BMP8B BMP8B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (880 aa)
INHBAInhibin subunit beta A. (426 aa)
NOTCH1Notch receptor 1. (2541 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1293 aa)
RBPMSRNA binding protein, mRNA processing factor. (219 aa)
GDF5Growth differentiation factor 5 (Predicted). (499 aa)
BMP4Bone morphogenetic protein 4, isoform 3 (Predicted). (408 aa)
FERMT1Fermitin family member 1. (663 aa)
ENSPANP00000018389TGF_BETA_2 domain-containing protein. (391 aa)
MSX1Msh homeobox 1. (284 aa)
CRB2Crumbs cell polarity complex component 2. (1290 aa)
FLCNFolliculin. (680 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
NODALNodal growth differentiation factor. (330 aa)
FBXL15F-box and leucine rich repeat protein 15. (300 aa)
SLC2A10Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (624 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1241 aa)
GDF2Growth differentiation factor 2. (429 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
FKBP8Peptidylprolyl isomerase. (421 aa)
SNW1SNW domain containing 1. (571 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSPANP00000024775Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (468 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
FOXD1Uncharacterized protein. (417 aa)
ZNF423Zinc finger protein 423. (1300 aa)
C20orf27Chromosome 20 open reading frame 27. (199 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
THBS1Thrombospondin 1. (1175 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2127 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (237 aa)
INHBBInhibin subunit beta B. (407 aa)
ENSPANP00000033178C2H2-type domain-containing protein. (229 aa)
ENSPANP00000036120TPR_REGION domain-containing protein. (132 aa)
BMP5Bone morphogenetic protein 5. (471 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
ENSPANP00000036680PDZ domain-containing protein. (290 aa)
ENGZP domain-containing protein. (274 aa)
SMAD2Mothers against decapentaplegic homolog. (472 aa)
KCPKielin cysteine rich BMP regulator. (1630 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (500 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
ENSPANP00000039827HATPase_c domain-containing protein. (427 aa)
ENSPANP00000040479PDZ domain-containing protein. (263 aa)
INHBEInhibin subunit beta E. (351 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MYOCDMyocardin. (984 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
JAK2Tyrosine-protein kinase. (1133 aa)
HIPK2Homeodomain interacting protein kinase 2. (1158 aa)
GDF7Growth differentiation factor 7. (447 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1315 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
NEO1Neogenin 1. (1465 aa)
RNF111Ring finger protein 111. (985 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (348 aa)
CREBBPCREB binding protein. (2442 aa)
KIAA0319KIAA0319. (1073 aa)
BMP6Bone morphogenetic protein 6. (515 aa)
AXIN1Axin 1, isoform 1 (Predicted). (867 aa)
EP300E1A binding protein p300. (2427 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
ADAM17ADAM metallopeptidase domain 17. (1005 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (1009 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa)
DAB2DAB adaptor protein 2. (770 aa)
GIPC3GIPC PDZ domain containing family member 3. (312 aa)
MEN1Uncharacterized protein. (610 aa)
CCN1Cellular communication network factor 1. (381 aa)
INHBCInhibin subunit beta C. (352 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (437 aa)
GDF3Growth differentiation factor 3. (335 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (383 aa)
GIPC2GIPC PDZ domain containing family member 2. (315 aa)
CDKN1CCyclin dependent kinase inhibitor 1C. (325 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
LOC101011710Left-right determination factor. (366 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
GATA4GATA binding protein 4. (442 aa)
TBX20T-box transcription factor 20. (447 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
KIAA1324LKIAA1324 like. (1028 aa)
NOTCH2Notch receptor 2. (2603 aa)
SDCBPSyndecan binding protein. (318 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
GDF6Growth differentiation factor 6. (455 aa)
GDF11Growth differentiation factor 11. (406 aa)
GATA6GATA binding protein 6. (595 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
RNF165Ring finger protein 165. (346 aa)
ZC3H3Zinc finger CCCH-type containing 3. (950 aa)
ING2Inhibitor of growth protein. (280 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
ENSPANP00000001806PDZ domain-containing protein. (258 aa)
LOC101011357Left-right determination factor. (366 aa)
BMP8BTGF_BETA_2 domain-containing protein. (402 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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