STRINGSTRING
GAS6 GAS6 PDPK1 PDPK1 FGF21 FGF21 IL10 IL10 ANGPT1 ANGPT1 TNIP2 TNIP2 GATA2 GATA2 ANGPTL4 ANGPTL4 FGB FGB PAK4 PAK4 IL13 IL13 IL4 IL4 NDNF NDNF CDH5 CDH5 KDR KDR TNFAIP3 TNFAIP3 FGA FGA FGG FGG KRIT1 KRIT1 BRAF BRAF TEK TEK MAPK7 MAPK7 GATA3 GATA3 SERPINE1 SERPINE1 LOC110742198 LOC110742198 RAMP2 RAMP2 SEMA5A SEMA5A ABL1 ABL1 ENSPANP00000035911 ENSPANP00000035911 NFE2L2 NFE2L2 TERT TERT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAS6Growth arrest specific 6. (679 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (347 aa)
FGF21Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family. (174 aa)
IL10Interleukin 10. (178 aa)
ANGPT1Angiopoietin 1. (498 aa)
TNIP2TNFAIP3 interacting protein 2. (429 aa)
GATA2GATA binding protein 2. (480 aa)
ANGPTL4Angiopoietin like 4. (340 aa)
FGBFibrinogen beta chain. (491 aa)
PAK4Non-specific serine/threonine protein kinase. (597 aa)
IL13Uncharacterized protein. (146 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (153 aa)
NDNFNeuron derived neurotrophic factor. (568 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1315 aa)
TNFAIP3TNF alpha induced protein 3. (804 aa)
FGAFibrinogen alpha chain. (861 aa)
FGGFibrinogen gamma chain. (437 aa)
KRIT1Uncharacterized protein. (736 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
GATA3GATA binding protein 3. (444 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (429 aa)
LOC110742198CCHC NOA-type domain-containing protein. (361 aa)
RAMP2Receptor activity modifying protein 2. (180 aa)
SEMA5ASemaphorin 5A. (1074 aa)
ABL1Tyrosine-protein kinase. (1112 aa)
ENSPANP00000035911Protein kinase domain-containing protein. (137 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (596 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1152 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.