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| | ACP5 | Tartrate-resistant acid phosphatase type 5. (325 aa) |
| | BCO2 | Beta-carotene oxygenase 2. (579 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | UCP1 | Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa) |
| | CLEC7A | C-type lectin domain containing 7A. (247 aa) |
| | BCL2 | BCL2 apoptosis regulator. (238 aa) |
| | LOC100998744 | Uncharacterized protein. (129 aa) |
| | HK2 | Hexokinase 2. (917 aa) |
| | ACOD1 | Aconitate decarboxylase 1. (481 aa) |
| | PAGE1 | PAGE family member 1. (144 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (601 aa) |
| | ADGRB1 | Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1581 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa) |
| | TUSC2 | Tumor suppressor 2, mitochondrial calcium regulator. (110 aa) |
| | ABCB7 | ATP binding cassette subfamily B member 7. (799 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (745 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | ENSPANP00000006009 | Uncharacterized protein. (310 aa) |
| | MMP3 | Matrix metallopeptidase 3. (477 aa) |
| | SLC30A10 | Solute carrier family 30 member 10. (485 aa) |
| | HDAC6 | Histone deacetylase 6. (1215 aa) |
| | PARL | Rhomboid domain-containing protein. (368 aa) |
| | PON2 | Paraoxonase 2. (375 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | PDK3 | Protein-serine/threonine kinase. (415 aa) |
| | COQ7 | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (217 aa) |
| | SLC25A33 | Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa) |
| | FOXO1 | Forkhead box O1. (655 aa) |
| | ENSPANP00000008508 | Uncharacterized protein. (270 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | ABCD2 | ATP binding cassette subfamily D member 2. (740 aa) |
| | VDAC1 | Voltage dependent anion channel 1. (289 aa) |
| | XDH | Xanthine dehydrogenase. (1333 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | SPHK2 | Sphingosine kinase 2. (653 aa) |
| | PLIN5 | Perilipin; Belongs to the perilipin family. (462 aa) |
| | ENSPANP00000010968 | Uncharacterized protein. (93 aa) |
| | HVCN1 | Hydrogen voltage gated channel 1. (273 aa) |
| | LOC101014578 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa) |
| | PIKFYVE | Phosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | MPV17 | Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (191 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa) |
| | ITGB2 | Integrin beta. (919 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | COA8 | Cytochrome c oxidase assembly factor 8. (206 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | TSPO | Translocator protein. (169 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (776 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (467 aa) |
| | TFAP2A | Transcription factor AP-2 alpha. (439 aa) |
| | SIRT5 | Sirtuin 5. (300 aa) |
| | TRAP1 | TNF receptor associated protein 1. (704 aa) |
| | LOC101025731 | Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (196 aa) |
| | DUOXA2 | Dual oxidase maturation factor 2. (320 aa) |
| | DUOXA1 | Dual oxidase maturation factor 1. (459 aa) |
| | RAB27A | RAB27A, member RAS oncogene family. (221 aa) |
| | BMP7 | Bone morphogenetic protein 7. (431 aa) |
| | STK17A | Serine/threonine kinase 17a; Belongs to the protein kinase superfamily. (414 aa) |
| | MMP8 | Matrix metallopeptidase 8. (467 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (270 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | BCR | BCR activator of RhoGEF and GTPase. (1083 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | BNIP3 | BCL2 interacting protein 3. (259 aa) |
| | ARG2 | Arginase. (354 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | NOXA1 | NADPH oxidase activator 1. (483 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (518 aa) |
| | PINK1 | PTEN induced kinase 1. (581 aa) |
| | CRP | Pentaxin. (224 aa) |
| | BST1 | Bone marrow stromal cell antigen 1. (315 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | CTNS | Cystinosin, lysosomal cystine transporter. (401 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) |
| | AATF | Apoptosis antagonizing transcription factor. (562 aa) |
| | PAX2 | Paired box 2. (436 aa) |
| | ENSPANP00000021195 | Uncharacterized protein. (58 aa) |
| | FOXM1 | Forkhead box M1. (767 aa) |
| | CYP2C8-2 | Uncharacterized protein. (283 aa) |
| | ENSPANP00000026528 | Rhomboid domain-containing protein. (375 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (832 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1857 aa) |
| | LOC100998278 | Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (196 aa) |
| | DCXR | Dicarbonyl and L-xylulose reductase. (244 aa) |
| | ENSPANP00000029172 | GAGE domain-containing protein. (68 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (836 aa) |
| | PID1 | Phosphotyrosine interaction domain containing 1. (250 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | THBS1 | Thrombospondin 1. (1175 aa) |
| | ENSPANP00000031498 | ABC transmembrane type-1 domain-containing protein. (466 aa) |
| | NOX5 | NADPH oxidase 5. (737 aa) |
| | ENSPANP00000031797 | Uncharacterized protein. (72 aa) |
| | G6PD | Uncharacterized protein. (561 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa) |
| | RNF41 | Ring finger protein 41. (317 aa) |
| | ROMO1 | Reactive oxygen species modulator 1. (79 aa) |
| | ZNF205 | Zinc finger protein 205. (555 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (596 aa) |
| | CYBA | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (195 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | MT3 | Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa) |
| | GRIN1 | Glutamate ionotropic receptor NMDA type subunit 1. (960 aa) |
| | AKR1C1 | Aldo-keto reductase family 1 member C3. (323 aa) |
| | GCH1 | GTP cyclohydrolase 1. (250 aa) |
| | SIRT2 | Sirtuin 2. (525 aa) |
| | F2 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (626 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (269 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | LOC101020215 | Peptidase S1 domain-containing protein. (428 aa) |
| | PON3 | Paraoxonase 3. (381 aa) |
