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GZMB | Granzyme B; Belongs to the peptidase S1 family. (281 aa) | ||||
PSMB11 | Proteasome subunit beta. (300 aa) | ||||
CARD8 | Uncharacterized protein. (444 aa) | ||||
BAD | BCL2 associated agonist of cell death. (168 aa) | ||||
KPNA1 | Importin subunit alpha; Functions in nuclear protein import. (538 aa) | ||||
ENSPANP00000000964 | AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa) | ||||
BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) | ||||
CDH1 | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa) | ||||
PSMA5 | Proteasome subunit alpha type. (241 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (238 aa) | ||||
LMNTD2 | Lamin tail domain containing 2. (644 aa) | ||||
PAK2 | Non-specific serine/threonine protein kinase. (524 aa) | ||||
TFDP2 | Transcription factor. (446 aa) | ||||
PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) | ||||
LMNA | Lamin A/C; Belongs to the intermediate filament family. (663 aa) | ||||
LOC101001750 | Uncharacterized protein. (210 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
LMNB1 | Lamin B1; Belongs to the intermediate filament family. (586 aa) | ||||
FNTA | Farnesyltransferase, CAAX box, alpha. (379 aa) | ||||
CASP9 | Caspase 9; Belongs to the peptidase C14A family. (416 aa) | ||||
TNFRSF10A | TNF receptor superfamily member 10a. (306 aa) | ||||
DSG1 | Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1046 aa) | ||||
PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) | ||||
DYNLL1 | Dynein light chain. (89 aa) | ||||
GSDME | Gasdermin E. (495 aa) | ||||
STK25 | Serine/threonine kinase 25. (426 aa) | ||||
TICAM2 | Toll like receptor adaptor molecule 2. (235 aa) | ||||
PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) | ||||
PSMB2 | Proteasome subunit beta. (201 aa) | ||||
TNFSF10 | Tumor necrosis factor ligand superfamily member. (281 aa) | ||||
H1-0 | H1 histone family member 0. (194 aa) | ||||
PSMA2 | Proteasome subunit alpha type. (234 aa) | ||||
MAP2 | Microtubule-associated protein. (1827 aa) | ||||
DFFB | DNA fragmentation factor subunit beta. (365 aa) | ||||
CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) | ||||
HMGB4 | High mobility group box 4. (191 aa) | ||||
CTNNB1 | Catenin beta 1. (781 aa) | ||||
LMNB2 | Lamin B2; Belongs to the intermediate filament family. (621 aa) | ||||
HP1BP3 | Heterochromatin protein 1 binding protein 3. (553 aa) | ||||
PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) | ||||
CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) | ||||
PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) | ||||
HMGB3 | Uncharacterized protein. (201 aa) | ||||
FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (282 aa) | ||||
DFFA | DNA fragmentation factor subunit alpha. (331 aa) | ||||
DSG3 | Desmoglein 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (999 aa) | ||||
PPP3CC | Serine/threonine-protein phosphatase. (520 aa) | ||||
LOC101000013 | Protein kinase domain-containing protein. (338 aa) | ||||
TFDP1 | Transcription factor. (410 aa) | ||||
TNFRSF10B | TNF receptor superfamily member 10b. (418 aa) | ||||
GAS2 | Growth arrest specific 2. (313 aa) | ||||
HMGB1 | High mobility group protein B1; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functio [...] (215 aa) | ||||
CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa) | ||||
OPA1 | OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa) | ||||
TICAM1 | Toll like receptor adaptor molecule 1. (521 aa) | ||||
PSMA8 | Proteasome subunit alpha type. (250 aa) | ||||
BMX | Tyrosine-protein kinase. (679 aa) | ||||
PSMD8 | Proteasome 26S subunit, non-ATPase 8. (294 aa) | ||||
DIABLO | Uncharacterized protein. (239 aa) | ||||
ACIN1 | Apoptotic chromatin condensation inducer 1. (1339 aa) | ||||
CASP7 | Caspase 7; Belongs to the peptidase C14A family. (336 aa) | ||||
DAPK3 | Death associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa) | ||||
LOC101025906 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
CASP6 | Caspase 6; Belongs to the peptidase C14A family. (291 aa) | ||||
LOC103876580 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
SFN | Stratifin; Belongs to the 14-3-3 family. (248 aa) | ||||
PSMC3 | AAA domain-containing protein; Belongs to the AAA ATPase family. (451 aa) | ||||
OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa) | ||||
PSMD9 | PDZ domain-containing protein. (223 aa) | ||||
LOC101005785 | Ubiquitin-like domain-containing protein. (156 aa) | ||||
EPPK1 | Epiplakin 1. (3527 aa) | ||||
ENSPANP00000009487 | annotation not available (214 aa) | ||||
ENSPANP00000009516 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (257 aa) | ||||
UNC5A | Unc-5 netrin receptor A. (914 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) | ||||
SH3GLB1 | SH3 domain containing GRB2 like, endophilin B1. (402 aa) | ||||
OMA1 | OMA1 zinc metallopeptidase. (524 aa) | ||||
TMEM198 | Transmembrane protein 198. (360 aa) | ||||
ENSPANP00000010220 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (257 aa) | ||||
ENSPANP00000010444 | Transcription factor. (392 aa) | ||||
APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (670 aa) | ||||
H1-5 | Histone cluster 1 H1 family member b. (226 aa) | ||||
NPVF | Neuropeptide VF precursor. (196 aa) | ||||
H1-4 | Histone cluster 1 H1 family member e. (219 aa) | ||||
LY96 | Lymphocyte antigen 96. (160 aa) | ||||
APIP | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa) | ||||
PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) | ||||
APC2 | APC regulator of WNT signaling pathway 2. (2301 aa) | ||||
PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) | ||||
PSMB8 | Proteasome subunit beta. (276 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
TRADD | TNFRSF1A associated via death domain. (308 aa) | ||||
YWHAH | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide (Predicted); Belongs to the 14-3-3 family. (246 aa) | ||||
PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1090 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
RIPK1 | Receptor interacting serine/threonine kinase 1. (776 aa) | ||||
DSP | Desmoplakin. (2871 aa) | ||||
LOC101008481 | Uncharacterized protein. (220 aa) | ||||
BCL2L10 | BCL2 like 10. (231 aa) | ||||
IGDCC3 | Immunoglobulin superfamily DCC subclass member 3. (809 aa) | ||||
IGDCC4 | Immunoglobulin superfamily DCC subclass member 4. (1250 aa) | ||||
UACA | Uveal autoantigen with coiled-coil domains and ankyrin repeats. (1418 aa) | ||||
PSMA4 | Proteasome subunit alpha type. (261 aa) | ||||
PSMA7 | Proteasome subunit alpha type. (248 aa) | ||||
VIM | Vimentin; Belongs to the intermediate filament family. (466 aa) | ||||
SCIN | Scinderin. (715 aa) | ||||
YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (246 aa) | ||||
PSMB5 | Proteasome subunit beta. (263 aa) | ||||
DBNL | Drebrin like. (440 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) | ||||
AVEN | Apoptosis and caspase activation inhibitor. (356 aa) | ||||
BMF | Bcl2 modifying factor. (206 aa) | ||||
PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) | ||||
E2F1 | E2F transcription factor 1. (423 aa) | ||||
BCL2L1 | BCL2 like 1. (233 aa) | ||||
PSMC6 | AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa) | ||||
PSMA3 | Proteasome subunit alpha type. (255 aa) | ||||
BID | BH3 interacting domain death agonist. (244 aa) | ||||
PSMB1 | Proteasome subunit beta. (241 aa) | ||||
ARHGAP10 | Rho GTPase activating protein 10. (786 aa) | ||||
PSME2 | Proteasome activator subunit 2. (239 aa) | ||||
YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) | ||||
ENSPANP00000017734 | Uncharacterized protein. (213 aa) | ||||
CLSPN | Claspin. (1340 aa) | ||||
DSG2 | Desmoglein 2. (1118 aa) | ||||
H1-8 | H1 histone family member O oocyte specific. (338 aa) | ||||
PSMB10 | Proteasome subunit beta. (273 aa) | ||||
BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa) | ||||
DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa) | ||||
ADD1 | Adducin 1. (768 aa) | ||||
CAPG | Capping actin protein, gelsolin like. (348 aa) | ||||
PSMB7 | Proteasome subunit beta. (302 aa) | ||||
ENSPANP00000019082 | Uncharacterized protein. (200 aa) | ||||
YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) | ||||
PLEC | Uncharacterized protein. (4680 aa) | ||||
ENSPANP00000019901 | Uncharacterized protein. (195 aa) | ||||
PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) | ||||
DYNLL2 | Dynein light chain. (89 aa) | ||||
UNC5B | Unc-5 netrin receptor B. (945 aa) | ||||
SEPTIN4 | Septin 4. (570 aa) | ||||
PSMB3 | Proteasome subunit beta. (205 aa) | ||||
GSDMA | Gasdermin A. (445 aa) | ||||
PSMD3 | Proteasome 26S subunit, non-ATPase 3. (552 aa) | ||||
FAS | Fas cell surface death receptor. (342 aa) | ||||
PSME3 | Proteasome activator subunit 3. (267 aa) | ||||
MAPT | Microtubule-associated protein. (776 aa) | ||||
PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (409 aa) | ||||
ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa) | ||||
GSDMB | Gasdermin B. (394 aa) | ||||
SEPTIN4-2 | Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (493 aa) | ||||
PSMA1 | Proteasome subunit alpha type. (269 aa) | ||||
ENSPANP00000022457 | Uncharacterized protein. (208 aa) | ||||
ENSPANP00000022572 | ANK_REP_REGION domain-containing protein. (170 aa) | ||||
ENSPANP00000022606 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (217 aa) | ||||
LOC101024029 | Proteasome subunit alpha type. (255 aa) | ||||
RPS27A | Ribosomal protein S27a. (156 aa) | ||||
PPP3R1 | Uncharacterized protein. (189 aa) | ||||
PSMD14 | Proteasome 26S subunit, non-ATPase 14. (315 aa) | ||||
BCAP31 | B cell receptor associated protein 31. (313 aa) | ||||
ENSPANP00000023349 | Dynein light chain. (80 aa) | ||||
STK24 | Protein kinase domain-containing protein. (443 aa) | ||||
STK26 | Serine/threonine kinase 26. (438 aa) | ||||
PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) | ||||
ENSPANP00000023895 | Uncharacterized protein. (191 aa) | ||||
TJP1 | Tight junction protein 1; Belongs to the MAGUK family. (1758 aa) | ||||
ENSPANP00000024698 | Uncharacterized protein. (212 aa) | ||||
LOC101008579 | Cytochrome c. (105 aa) | ||||
ENSPANP00000025126 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (209 aa) | ||||
DCC | DCC netrin 1 receptor. (1447 aa) | ||||
SEPTIN1 | Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (399 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) | ||||
TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa) | ||||
DAPK2 | Death associated protein kinase 2; Belongs to the protein kinase superfamily. (488 aa) | ||||
NMT1 | Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (496 aa) | ||||
ENSPANP00000027602 | MPN domain-containing protein. (149 aa) | ||||
PSME1 | Proteasome activator subunit 1. (249 aa) | ||||
PSMD5 | Proteasome 26S subunit, non-ATPase 5. (470 aa) | ||||
BOK | BCL2 family apoptosis regulator BOK. (212 aa) | ||||
ENSPANP00000029069 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (95 aa) | ||||
ENSPANP00000029162 | Uncharacterized protein; Belongs to the AAA ATPase family. (402 aa) | ||||
LOC101005491 | Uncharacterized protein. (433 aa) | ||||
ENSPANP00000029490 | Uncharacterized protein. (345 aa) | ||||
PSMD13 | Proteasome 26S subunit, non-ATPase 13. (378 aa) | ||||
TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (836 aa) | ||||
PSMD6 | Proteasome 26S subunit, non-ATPase 6. (442 aa) | ||||
ENSPANP00000030356 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (227 aa) | ||||
YWHAQ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (267 aa) | ||||
ENSPANP00000030575 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (218 aa) | ||||
DAPK1 | Death associated protein kinase 1. (1398 aa) | ||||
CD14 | CD14 molecule. (384 aa) | ||||
PSMF1 | Proteasome inhibitor subunit 1. (339 aa) | ||||
PSMB9 | Proteasome subunit beta. (219 aa) | ||||
ENSPANP00000031927 | Uncharacterized protein. (161 aa) | ||||
ENSPANP00000032176 | Ubiquitin-like domain-containing protein. (129 aa) | ||||
XIAP | X-linked inhibitor of apoptosis. (497 aa) | ||||
ENSPANP00000032731 | Uncharacterized protein. (401 aa) | ||||
KXD1 | Ubiquitin-like domain-containing protein. (232 aa) | ||||
ENSPANP00000033145 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (95 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
BNIP5 | BCL2 interacting protein 5. (650 aa) | ||||
PKP1 | Plakophilin 1. (747 aa) | ||||
YWHAG | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa) | ||||
ENSPANP00000034651 | CSN8_PSD8_EIF3K domain-containing protein. (249 aa) | ||||
ENSPANP00000034840 | 14_3_3 domain-containing protein. (68 aa) | ||||
ENSPANP00000034891 | Ubiquitin-like domain-containing protein. (156 aa) | ||||
PSME4 | Proteasome activator subunit 4. (1810 aa) | ||||
ENSPANP00000035552 | Prot_ATP_ID_OB domain-containing protein. (166 aa) | ||||
APPL1 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (715 aa) | ||||
ENSPANP00000035959 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (196 aa) | ||||
SH3GLB2 | SH3 domain containing GRB2 like, endophilin B2. (404 aa) | ||||
HMGB2 | High mobility group box 2. (210 aa) | ||||
TP53BP2 | Tumor protein p53 binding protein 2. (1160 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (203 aa) | ||||
ENSPANP00000036982 | AAA domain-containing protein. (402 aa) | ||||
PSMA6 | Proteasome subunit alpha type. (224 aa) | ||||
TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (686 aa) | ||||
PSMD4 | VWFA domain-containing protein. (380 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (770 aa) | ||||
C1QBP | Complement C1q binding protein. (169 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (467 aa) | ||||
PSMB6 | Proteasome subunit beta. (239 aa) | ||||
APC | APC regulator of WNT signaling pathway. (2871 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (211 aa) | ||||
SPTAN1 | Spectrin alpha, non-erythrocytic 1. (2498 aa) | ||||
LOC101014473 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) | ||||
PRKCQ | Protein kinase C. (753 aa) | ||||
BCAP29 | B cell receptor associated protein 29. (317 aa) | ||||
LOC101018182 | Microtubule-associated protein. (346 aa) | ||||
TJP2 | Uncharacterized protein; Belongs to the MAGUK family. (1247 aa) | ||||
TJP3 | Tight junction protein 3; Belongs to the MAGUK family. (939 aa) | ||||
ENSPANP00000041596 | AAA domain-containing protein; Belongs to the AAA ATPase family. (416 aa) | ||||
MAGED1 | MAGE family member D1. (834 aa) | ||||
APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) | ||||
ENSPANP00000042542 | Uncharacterized protein. (196 aa) | ||||
LMNTD1 | Lamin tail domain containing 1. (404 aa) | ||||
ENSPANP00000042759 | AAA domain-containing protein; Belongs to the AAA ATPase family. (319 aa) | ||||
PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa) | ||||
ENSPANP00000043416 | Ubiquitin-like domain-containing protein. (145 aa) | ||||
LOC100997529 | Cytochrome c. (105 aa) | ||||
GSDMD | Gasdermin D. (532 aa) | ||||
KPNB1 | Karyopherin subunit beta 1. (877 aa) | ||||
ENSPANP00000044875 | Uncharacterized protein. (202 aa) | ||||
LOC101014039 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
ENSPANP00000045264 | ANK_REP_REGION domain-containing protein. (116 aa) | ||||
GSN | Gelsolin. (809 aa) | ||||
ENSPANP00000045653 | CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (195 aa) | ||||
SEPTIN5 | Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (378 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
ENSPANP00000046336 | AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa) | ||||
LOC100997503 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa) | ||||
SATB1 | DNA-binding protein SATB. (795 aa) | ||||
LOC101021327 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) | ||||
PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (461 aa) | ||||
LOC101015970 | Proteasome endopeptidase complex. (221 aa) |