STRINGSTRING
PPP1R15A PPP1R15A XPO1 XPO1 ENSPANP00000002997 ENSPANP00000002997 TGFB1 TGFB1 USP15 USP15 SMAD7 SMAD7 TGFBR2 TGFBR2 LOC101005785 LOC101005785 LOC101022082 LOC101022082 PPP1CA PPP1CA STUB1 STUB1 SMAD3 SMAD3 PMEPA1 PMEPA1 SMURF1 SMURF1 BAMBI BAMBI MTMR4 MTMR4 RPS27A RPS27A LOC101018157 LOC101018157 LDLRAD4 LDLRAD4 SMURF2 SMURF2 ENSPANP00000032176 ENSPANP00000032176 KXD1 KXD1 ENSPANP00000033301 ENSPANP00000033301 ENSPANP00000034891 ENSPANP00000034891 PPP1CB PPP1CB SMAD2 SMAD2 NEDD4L NEDD4L ENSPANP00000038653 ENSPANP00000038653 STRAP STRAP ENSPANP00000043416 ENSPANP00000043416 PPP1CC PPP1CC TGFBR1 TGFBR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (629 aa)
XPO1Exportin 1. (1071 aa)
ENSPANP00000002997Ubiquitin-like domain-containing protein. (127 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
SMAD7Mothers against decapentaplegic homolog. (493 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LOC101005785Ubiquitin-like domain-containing protein. (156 aa)
LOC101022082Ubiquitin-like domain-containing protein. (128 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
STUB1STIP1 homology and U-box containing protein 1. (305 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (287 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
MTMR4Myotubularin related protein 4. (1195 aa)
RPS27ARibosomal protein S27a. (156 aa)
LOC101018157Ubiquitin-like domain-containing protein. (140 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (306 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (682 aa)
ENSPANP00000032176Ubiquitin-like domain-containing protein. (129 aa)
KXD1Ubiquitin-like domain-containing protein. (232 aa)
ENSPANP00000033301Uncharacterized protein. (315 aa)
ENSPANP00000034891Ubiquitin-like domain-containing protein. (156 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (328 aa)
SMAD2Mothers against decapentaplegic homolog. (472 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1259 aa)
ENSPANP00000038653Ubiquitin-like domain-containing protein. (124 aa)
STRAPSerine/threonine kinase receptor associated protein. (363 aa)
ENSPANP00000043416Ubiquitin-like domain-containing protein. (145 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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