86 items (Papio anubis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RHOB	Ras homolog family member B. (196 aa)
	TYROBP	TYRO protein tyrosine kinase binding protein. (144 aa)
	PLXNA1	Plexin A1. (2042 aa)
	ENSPANP00000043785	Uncharacterized protein. (385 aa)
	LIMK2	LIM domain kinase 2. (638 aa)
	LIMK1	LIM domain kinase 1. (677 aa)
	ENSPANP00000042915	HATPase_c domain-containing protein. (401 aa)
	CFL1	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (196 aa)
	TLN1	Talin 1. (2558 aa)
	RHOA	Ras homolog family member A. (193 aa)
	ENSPANP00000039827	HATPase_c domain-containing protein. (427 aa)
	ENSPANP00000039822	ADF-H domain-containing protein. (135 aa)
	CRMP1	Collapsin response mediator protein 1. (624 aa)
	ENSPANP00000039260	Uncharacterized protein. (117 aa)
	SEMA3E	Semaphorin 3E; Belongs to the semaphorin family. (775 aa)
	ENSPANP00000038105	HATPase_c domain-containing protein. (598 aa)
	ERBB2	Receptor protein-tyrosine kinase. (1399 aa)
	ENSPANP00000036814	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (209 aa)
	MYH14	Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa)
	ENSPANP00000035674	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (158 aa)
	ENSPANP00000035354	Uncharacterized protein. (273 aa)
	DPYSL4	Dihydropyrimidinase like 4. (581 aa)
	MYH11	Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1985 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1313 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (801 aa)
	ENSPANP00000032717	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (138 aa)
	MET	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1404 aa)
	SEMA5A	Semaphorin 5A. (1074 aa)
	ENSPANP00000029897	Uncharacterized protein. (115 aa)
	PIP5K1C	Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (708 aa)
	PAK3	P21 (RAC1) activated kinase 3. (580 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
	ENSPANP00000025762	Uncharacterized protein. (157 aa)
	DPYSL3	Dihydropyrimidinase like 3. (684 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (923 aa)
	MYH10	Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (862 aa)
	CD72	CD72 molecule. (359 aa)
	DPYSL2	Dihydropyrimidinase like 2. (677 aa)
	DPYSL5	Dihydropyrimidinase like 5. (565 aa)
	SEMA3B	Semaphorin 3B; Belongs to the semaphorin family. (783 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	DSTN	Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (165 aa)
	MYL9	Myosin light chain 9. (172 aa)
	PLXNB1	Plexin B1. (2136 aa)
	SEMA4B	Semaphorin 4B; Belongs to the semaphorin family. (831 aa)
	SEMA7A	Semaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (668 aa)
	TLN2	Talin 2. (2545 aa)
	SEMA6D	Semaphorin 6D; Belongs to the semaphorin family. (1076 aa)
	CFL2	Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
	PLXNB2	Plexin B2. (1852 aa)
	FES	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (816 aa)
	HSP90AA1	Heat shock protein 90 alpha family class A member 1. (831 aa)
	MYH9	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1962 aa)
	ROCK2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
	PKHD1	PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4072 aa)
	HSP90AB1	Heat shock protein 90 alpha family class B member 1. (724 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (230 aa)
	PLXNA4	Plexin A4. (1950 aa)
	SEMA6A	Semaphorin 6A; Belongs to the semaphorin family. (1047 aa)
	ENSPANP00000010678	Uncharacterized protein. (152 aa)
	CDK5R1	Cyclin-dependent kinase 5 activator. (307 aa)
	PLXNA2	Plexin A2. (1909 aa)
	RND1	Rho family GTPase 1. (232 aa)
	ARHGAP35	Rho GTPase activating protein 35. (1499 aa)
	FARP2	FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1032 aa)
	SEMA4A	Semaphorin 4A; Belongs to the semaphorin family. (760 aa)
	PKHD1L1	PKHD1 like 1. (4247 aa)
	ARHGEF11	Rho guanine nucleotide exchange factor 11. (1550 aa)
	PAK1	Non-specific serine/threonine protein kinase. (545 aa)
	PLXNA3	Plexin A3. (1860 aa)
	SEMA6C	Sema domain-containing protein; Belongs to the semaphorin family. (962 aa)
	SEMA3A	Semaphorin 3A; Belongs to the semaphorin family. (772 aa)
	SEMA3G	Semaphorin 3G; Belongs to the semaphorin family. (782 aa)
	RRAS	RAS related. (218 aa)
	PLXNB3	Plexin B3. (1909 aa)
	PLXNC1	Plexin C1. (1590 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (302 aa)
	MYL6	Uncharacterized protein. (218 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	SEMA6B	Semaphorin 6B; Belongs to the semaphorin family. (841 aa)
	ITGA1	Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1164 aa)
	RHOC	Ras homolog family member C. (193 aa)
	ARHGEF12	Rho guanine nucleotide exchange factor 12. (1517 aa)
	PLXND1	Plexin D1. (1924 aa)

Your Current Organism:

Papio anubis

NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP35	CFL2	ENSPANP00000008357	ENSPANP00000013982	Rho GTPase activating protein 35.	Cofilin 2; Belongs to the actin-binding proteins ADF family.	0.560
ARHGAP35	FYN	ENSPANP00000008357	ENSPANP00000017299	Rho GTPase activating protein 35.	Tyrosine-protein kinase.	0.571
ARHGAP35	MET	ENSPANP00000008357	ENSPANP00000030652	Rho GTPase activating protein 35.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.642
ARHGAP35	MYH10	ENSPANP00000008357	ENSPANP00000019678	Rho GTPase activating protein 35.	Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.561
ARHGAP35	PLXNB1	ENSPANP00000008357	ENSPANP00000015672	Rho GTPase activating protein 35.	Plexin B1.	0.495
ARHGAP35	PLXNB2	ENSPANP00000008357	ENSPANP00000013684	Rho GTPase activating protein 35.	Plexin B2.	0.477
ARHGAP35	PLXNB3	ENSPANP00000008357	ENSPANP00000003889	Rho GTPase activating protein 35.	Plexin B3.	0.471
ARHGAP35	RHOA	ENSPANP00000008357	ENSPANP00000039995	Rho GTPase activating protein 35.	Ras homolog family member A.	0.988
ARHGAP35	RHOB	ENSPANP00000008357	ENSPANP00000000107	Rho GTPase activating protein 35.	Ras homolog family member B.	0.883
ARHGAP35	RHOC	ENSPANP00000008357	ENSPANP00000000823	Rho GTPase activating protein 35.	Ras homolog family member C.	0.930
ARHGAP35	RND1	ENSPANP00000008357	ENSPANP00000009777	Rho GTPase activating protein 35.	Rho family GTPase 1.	0.842
ARHGAP35	SEMA4D	ENSPANP00000008357	ENSPANP00000019356	Rho GTPase activating protein 35.	Semaphorin 4D; Belongs to the semaphorin family.	0.559
ARHGEF11	ARHGEF12	ENSPANP00000006706	ENSPANP00000000625	Rho guanine nucleotide exchange factor 11.	Rho guanine nucleotide exchange factor 12.	0.914
ARHGEF11	ERBB2	ENSPANP00000006706	ENSPANP00000037255	Rho guanine nucleotide exchange factor 11.	Receptor protein-tyrosine kinase.	0.503
ARHGEF11	MET	ENSPANP00000006706	ENSPANP00000030652	Rho guanine nucleotide exchange factor 11.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.512
ARHGEF11	PLXNB1	ENSPANP00000006706	ENSPANP00000015672	Rho guanine nucleotide exchange factor 11.	Plexin B1.	0.872
ARHGEF11	PLXNB2	ENSPANP00000006706	ENSPANP00000013684	Rho guanine nucleotide exchange factor 11.	Plexin B2.	0.948
ARHGEF11	PLXNB3	ENSPANP00000006706	ENSPANP00000003889	Rho guanine nucleotide exchange factor 11.	Plexin B3.	0.737
ARHGEF11	PLXND1	ENSPANP00000006706	ENSPANP00000000409	Rho guanine nucleotide exchange factor 11.	Plexin D1.	0.402
ARHGEF11	RHOA	ENSPANP00000006706	ENSPANP00000039995	Rho guanine nucleotide exchange factor 11.	Ras homolog family member A.	0.993

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