STRINGSTRING
ENSPANP00000025762 ENSPANP00000025762 ENSPANP00000029897 ENSPANP00000029897 MET MET MYH11 MYH11 MYH14 MYH14 ERBB2 ERBB2 RHOA RHOA LIMK1 LIMK1 LIMK2 LIMK2 RND1 RND1 ARHGAP35 ARHGAP35 ARHGEF11 ARHGEF11 RRAS RRAS MYL6 MYL6 RHOC RHOC ARHGEF12 ARHGEF12 RHOB RHOB ENSPANP00000010678 ENSPANP00000010678 ROCK2 ROCK2 MYH9 MYH9 PLXNB1 PLXNB1 MYL9 MYL9 SEMA4D SEMA4D MYH10 MYH10 ROCK1 ROCK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPANP00000025762Uncharacterized protein. (157 aa)
ENSPANP00000029897Uncharacterized protein. (115 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1404 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1985 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa)
ERBB2Receptor protein-tyrosine kinase. (1399 aa)
RHOARas homolog family member A. (193 aa)
LIMK1LIM domain kinase 1. (677 aa)
LIMK2LIM domain kinase 2. (638 aa)
RND1Rho family GTPase 1. (232 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1550 aa)
RRASRAS related. (218 aa)
MYL6Uncharacterized protein. (218 aa)
RHOCRas homolog family member C. (193 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1517 aa)
RHOBRas homolog family member B. (196 aa)
ENSPANP00000010678Uncharacterized protein. (152 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1962 aa)
PLXNB1Plexin B1. (2136 aa)
MYL9Myosin light chain 9. (172 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
Server load: low (34%) [HD]